Fluorine in PDB 1k8w: Crystal Structure of the E. Coli Pseudouridine Synthase Trub Bound to A T Stem-Loop Rna

All present enzymatic activity of Crystal Structure of the E. Coli Pseudouridine Synthase Trub Bound to A T Stem-Loop Rna:
4.2.1.70;

The structure of Crystal Structure of the E. Coli Pseudouridine Synthase Trub Bound to A T Stem-Loop Rna, PDB code: 1k8w was solved by C.Hoang, A.R.Ferre-D'amare, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	28.27 / 1.85
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	145.054, 40.361, 77.987, 90.00, 110.60, 90.00
R / Rfree (%)	18.4 / 21.1

The binding sites of Fluorine atom in the Crystal Structure of the E. Coli Pseudouridine Synthase Trub Bound to A T Stem-Loop Rna (pdb code 1k8w). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Crystal Structure of the E. Coli Pseudouridine Synthase Trub Bound to A T Stem-Loop Rna, PDB code: 1k8w:

Fluorine binding site 1 out of 1 in the Crystal Structure of the E. Coli Pseudouridine Synthase Trub Bound to A T Stem-Loop Rna


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Crystal Structure of the E. Coli Pseudouridine Synthase Trub Bound to A T Stem-Loop Rna within 5.0Å range: probe atom residue distance (Å) B Occ B:F410 b:24.2 occ:1.00 F5 B:FHU410 0.0 24.2 1.0 C5 B:FHU410 1.4 21.9 1.0 C4 B:FHU410 2.4 22.1 1.0 C6 B:FHU410 2.4 24.7 1.0 C1' B:FHU410 2.4 22.3 1.0 O6 B:FHU410 2.7 30.8 1.0 O4 B:FHU410 2.7 23.8 1.0 O4' B:FHU410 3.0 21.5 1.0 OH A:TYR76 3.0 21.1 1.0 C2' B:FHU410 3.2 20.8 1.0 CD2 A:LEU47 3.3 17.3 1.0 CE2 A:TYR76 3.3 19.0 1.0 O A:ALA46 3.4 18.9 1.0 CZ A:TYR76 3.5 20.1 1.0 N3 B:FHU410 3.7 22.9 1.0 N1 B:FHU410 3.7 25.2 1.0 C5' B:FHU410 3.8 17.7 1.0 C4' B:FHU410 3.8 17.4 1.0 NH1 A:ARG202 4.1 17.5 1.0 C3' B:FHU410 4.1 19.0 1.0 CA A:LEU47 4.1 17.1 1.0 O2' B:FHU410 4.2 24.5 1.0 C2 B:FHU410 4.2 24.0 1.0 O A:HOH518 4.2 19.9 1.0 CD2 A:TYR76 4.4 19.5 1.0 C A:ALA46 4.4 19.8 1.0 O5' B:FHU410 4.4 15.4 1.0 CG A:LEU47 4.5 17.0 1.0 CE1 A:TYR76 4.7 17.8 1.0 CB A:LEU47 4.8 16.8 1.0 N A:LEU47 4.8 16.8 1.0 CZ A:ARG202 4.9 20.0 1.0 N A:ASP48 5.0 16.1 1.0

C.Hoang, A.R.Ferre-D'amare. Cocrystal Structure of A Trna PSI55 Pseudouridine Synthase: Nucleotide Flipping By An Rna-Modifying Enzyme. Cell(Cambridge,Mass.) V. 107 929 2001.
ISSN: ISSN 0092-8674
PubMed: 11779468
DOI: 10.1016/S0092-8674(01)00618-3