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Atomistry » Fluorine » PDB 1mmd-1o5f » 1nhu | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 1mmd-1o5f » 1nhu » |
Fluorine in PDB 1nhu: Hepatitis C Virus Rna Polymerase in Complex with Non-Nucleoside Analogue InhibitorEnzymatic activity of Hepatitis C Virus Rna Polymerase in Complex with Non-Nucleoside Analogue Inhibitor
All present enzymatic activity of Hepatitis C Virus Rna Polymerase in Complex with Non-Nucleoside Analogue Inhibitor:
2.7.7.48; Protein crystallography data
The structure of Hepatitis C Virus Rna Polymerase in Complex with Non-Nucleoside Analogue Inhibitor, PDB code: 1nhu
was solved by
M.Wang,
K.K.S.Ng,
M.M.Cherney,
L.Chan,
C.G.Yannopoulos,
J.Bedard,
N.Morin,
N.Nguyen-Ba,
M.H.Alaoui-Ismaili,
R.C.Bethell,
M.N.G.James,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 1nhu:
The structure of Hepatitis C Virus Rna Polymerase in Complex with Non-Nucleoside Analogue Inhibitor also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Hepatitis C Virus Rna Polymerase in Complex with Non-Nucleoside Analogue Inhibitor
(pdb code 1nhu). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 6 binding sites of Fluorine where determined in the Hepatitis C Virus Rna Polymerase in Complex with Non-Nucleoside Analogue Inhibitor, PDB code: 1nhu: Jump to Fluorine binding site number: 1; 2; 3; 4; 5; 6; Fluorine binding site 1 out of 6 in 1nhuGo back to Fluorine Binding Sites List in 1nhu
Fluorine binding site 1 out
of 6 in the Hepatitis C Virus Rna Polymerase in Complex with Non-Nucleoside Analogue Inhibitor
Mono view Stereo pair view
Fluorine binding site 2 out of 6 in 1nhuGo back to Fluorine Binding Sites List in 1nhu
Fluorine binding site 2 out
of 6 in the Hepatitis C Virus Rna Polymerase in Complex with Non-Nucleoside Analogue Inhibitor
Mono view Stereo pair view
Fluorine binding site 3 out of 6 in 1nhuGo back to Fluorine Binding Sites List in 1nhu
Fluorine binding site 3 out
of 6 in the Hepatitis C Virus Rna Polymerase in Complex with Non-Nucleoside Analogue Inhibitor
Mono view Stereo pair view
Fluorine binding site 4 out of 6 in 1nhuGo back to Fluorine Binding Sites List in 1nhu
Fluorine binding site 4 out
of 6 in the Hepatitis C Virus Rna Polymerase in Complex with Non-Nucleoside Analogue Inhibitor
Mono view Stereo pair view
Fluorine binding site 5 out of 6 in 1nhuGo back to Fluorine Binding Sites List in 1nhu
Fluorine binding site 5 out
of 6 in the Hepatitis C Virus Rna Polymerase in Complex with Non-Nucleoside Analogue Inhibitor
Mono view Stereo pair view
Fluorine binding site 6 out of 6 in 1nhuGo back to Fluorine Binding Sites List in 1nhu
Fluorine binding site 6 out
of 6 in the Hepatitis C Virus Rna Polymerase in Complex with Non-Nucleoside Analogue Inhibitor
Mono view Stereo pair view
Reference:
M.Wang,
K.K.S.Ng,
M.M.Cherney,
L.Chan,
C.G.Yannopoulos,
J.Bedard,
N.Morin,
N.Nguyen-Ba,
M.H.Alaoui-Ismaili,
R.C.Bethell,
M.N.G.James.
Non-Nucleoside Analogue Inhibitors Bind to An Allosteric Site on Hcv NS5B Polymerase: Crystal Structures and Mechanism of Inhibition J.Biol.Chem. V. 278 9489 2003.
Page generated: Wed Jul 31 12:07:50 2024
ISSN: ISSN 0021-9258 PubMed: 12509436 DOI: 10.1074/JBC.M209397200 |
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