Atomistry » Fluorine » PDB 1o5g-1q6m » 1oh9
Atomistry »
  Fluorine »
    PDB 1o5g-1q6m »
      1oh9 »

Fluorine in PDB 1oh9: Acetylglutamate Kinase From Escherichia Coli Complexed with Mgadp, N- Acetyl-L-Glutamate and the Transition-State Mimic ALF4-

Enzymatic activity of Acetylglutamate Kinase From Escherichia Coli Complexed with Mgadp, N- Acetyl-L-Glutamate and the Transition-State Mimic ALF4-

All present enzymatic activity of Acetylglutamate Kinase From Escherichia Coli Complexed with Mgadp, N- Acetyl-L-Glutamate and the Transition-State Mimic ALF4-:
2.7.2.8;

Protein crystallography data

The structure of Acetylglutamate Kinase From Escherichia Coli Complexed with Mgadp, N- Acetyl-L-Glutamate and the Transition-State Mimic ALF4-, PDB code: 1oh9 was solved by F.Gil-Ortiz, S.Ramon-Maiques, I.Fita, V.Rubio, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 30.00 / 1.91
Space group C 2 2 21
Cell size a, b, c (Å), α, β, γ (°) 59.457, 72.220, 107.214, 90.00, 90.00, 90.00
R / Rfree (%) 18.6 / 22.9

Other elements in 1oh9:

The structure of Acetylglutamate Kinase From Escherichia Coli Complexed with Mgadp, N- Acetyl-L-Glutamate and the Transition-State Mimic ALF4- also contains other interesting chemical elements:

Magnesium (Mg) 1 atom
Aluminium (Al) 1 atom

Fluorine Binding Sites:

The binding sites of Fluorine atom in the Acetylglutamate Kinase From Escherichia Coli Complexed with Mgadp, N- Acetyl-L-Glutamate and the Transition-State Mimic ALF4- (pdb code 1oh9). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 4 binding sites of Fluorine where determined in the Acetylglutamate Kinase From Escherichia Coli Complexed with Mgadp, N- Acetyl-L-Glutamate and the Transition-State Mimic ALF4-, PDB code: 1oh9:
Jump to Fluorine binding site number: 1; 2; 3; 4;

Fluorine binding site 1 out of 4 in 1oh9

Go back to Fluorine Binding Sites List in 1oh9
Fluorine binding site 1 out of 4 in the Acetylglutamate Kinase From Escherichia Coli Complexed with Mgadp, N- Acetyl-L-Glutamate and the Transition-State Mimic ALF4-


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Acetylglutamate Kinase From Escherichia Coli Complexed with Mgadp, N- Acetyl-L-Glutamate and the Transition-State Mimic ALF4- within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F1261

b:70.2
occ:1.00
 F1 A:ALF1261 0.0 70.2 1.0
AL A:ALF1261 1.8 43.0 1.0
F4 A:ALF1261 2.4 58.8 1.0
F3 A:ALF1261 2.6 60.6 1.0
O3B A:ADP1259 2.6 53.2 1.0
N A:GLY11 2.9 23.8 1.0
OE2 A:NLG1260 2.9 16.5 1.0
N A:GLY44 3.1 18.8 1.0
CA A:GLY10 3.1 21.0 1.0
C A:GLY10 3.4 23.4 1.0
F2 A:ALF1261 3.5 51.0 1.0
N A:GLY45 3.6 23.2 1.0
CA A:GLY44 3.8 20.3 1.0
C A:GLY43 3.9 16.3 1.0
CA A:GLY43 4.0 14.4 1.0
CA A:GLY11 4.0 24.4 1.0
CD A:NLG1260 4.0 14.7 1.0
PB A:ADP1259 4.2 53.0 1.0
C A:GLY44 4.2 20.9 1.0
O A:GLY11 4.3 24.3 1.0
N A:GLY10 4.5 17.8 1.0
OE1 A:NLG1260 4.5 14.9 1.0
N A:GLY43 4.6 13.3 1.0
C A:GLY11 4.6 23.7 1.0
CA A:GLY45 4.6 26.7 1.0
O A:LEU9 4.6 14.1 1.0
NZ A:LYS8 4.6 13.4 1.0
O A:GLY10 4.7 23.0 1.0
CD1 A:LEU14 4.8 40.5 1.0
O2B A:ADP1259 4.8 53.4 1.0
O1B A:ADP1259 4.9 52.8 1.0
O3A A:ADP1259 4.9 54.0 1.0
O A:GLY43 4.9 14.1 1.0

Fluorine binding site 2 out of 4 in 1oh9

Go back to Fluorine Binding Sites List in 1oh9
Fluorine binding site 2 out of 4 in the Acetylglutamate Kinase From Escherichia Coli Complexed with Mgadp, N- Acetyl-L-Glutamate and the Transition-State Mimic ALF4-


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Acetylglutamate Kinase From Escherichia Coli Complexed with Mgadp, N- Acetyl-L-Glutamate and the Transition-State Mimic ALF4- within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F1261

b:51.0
occ:1.00
 F2 A:ALF1261 0.0 51.0 1.0
AL A:ALF1261 1.8 43.0 1.0
F3 A:ALF1261 2.5 60.6 1.0
O A:HOH2210 2.5 19.2 1.0
MG A:MG1262 2.5 55.3 1.0
F4 A:ALF1261 2.6 58.8 1.0
O3B A:ADP1259 2.7 53.2 1.0
OE2 A:NLG1260 2.7 16.5 1.0
OE1 A:NLG1260 2.7 14.9 1.0
CD A:NLG1260 3.1 14.7 1.0
O1B A:ADP1259 3.2 52.8 1.0
O A:HOH2208 3.3 35.6 1.0
PB A:ADP1259 3.4 53.0 1.0
F1 A:ALF1261 3.5 70.2 1.0
O3A A:ADP1259 3.6 54.0 1.0
O2A A:ADP1259 3.7 55.5 1.0
PA A:ADP1259 4.3 54.8 1.0
NZ A:LYS8 4.4 13.4 1.0
O A:HOH2143 4.4 27.4 1.0
CG A:NLG1260 4.4 14.0 1.0
ND2 A:ASN160 4.5 13.7 1.0
O A:HOH2209 4.6 31.4 1.0
O2B A:ADP1259 4.8 53.4 1.0

Fluorine binding site 3 out of 4 in 1oh9

Go back to Fluorine Binding Sites List in 1oh9
Fluorine binding site 3 out of 4 in the Acetylglutamate Kinase From Escherichia Coli Complexed with Mgadp, N- Acetyl-L-Glutamate and the Transition-State Mimic ALF4-


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of Acetylglutamate Kinase From Escherichia Coli Complexed with Mgadp, N- Acetyl-L-Glutamate and the Transition-State Mimic ALF4- within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F1261

b:60.6
occ:1.00
 F3 A:ALF1261 0.0 60.6 1.0
AL A:ALF1261 1.8 43.0 1.0
F2 A:ALF1261 2.5 51.0 1.0
F1 A:ALF1261 2.6 70.2 1.0
O A:HOH2210 2.7 19.2 1.0
NZ A:LYS8 2.7 13.4 1.0
O3B A:ADP1259 2.8 53.2 1.0
OE2 A:NLG1260 2.8 16.5 1.0
OE1 A:NLG1260 2.9 14.9 1.0
CD A:NLG1260 3.1 14.7 1.0
CE A:LYS8 3.4 13.5 1.0
O1B A:ADP1259 3.5 52.8 1.0
CB A:ALA161 3.6 11.6 1.0
F4 A:ALF1261 3.6 58.8 1.0
CA A:GLY43 3.7 14.4 1.0
PB A:ADP1259 3.7 53.0 1.0
CA A:GLY10 3.8 21.0 1.0
MG A:MG1262 4.1 55.3 1.0
N A:GLY43 4.2 13.3 1.0
N A:GLY44 4.3 18.8 1.0
O A:HOH2153 4.4 29.9 1.0
O A:LEU9 4.5 14.1 1.0
C A:GLY43 4.5 16.3 1.0
CG A:NLG1260 4.5 14.0 1.0
N A:GLY11 4.6 23.8 1.0
O2B A:ADP1259 4.7 53.4 1.0
CA A:ALA161 4.7 12.1 1.0
C A:GLY10 4.7 23.4 1.0
CD A:LYS8 4.7 12.5 1.0
N A:GLY10 4.8 17.8 1.0
O3A A:ADP1259 4.8 54.0 1.0
N A:ALA161 4.8 10.4 1.0
C A:LEU9 5.0 14.8 1.0

Fluorine binding site 4 out of 4 in 1oh9

Go back to Fluorine Binding Sites List in 1oh9
Fluorine binding site 4 out of 4 in the Acetylglutamate Kinase From Escherichia Coli Complexed with Mgadp, N- Acetyl-L-Glutamate and the Transition-State Mimic ALF4-


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 4 of Acetylglutamate Kinase From Escherichia Coli Complexed with Mgadp, N- Acetyl-L-Glutamate and the Transition-State Mimic ALF4- within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F1261

b:58.8
occ:1.00
 F4 A:ALF1261 0.0 58.8 1.0
AL A:ALF1261 1.8 43.0 1.0
F1 A:ALF1261 2.4 70.2 1.0
O3B A:ADP1259 2.5 53.2 1.0
F2 A:ALF1261 2.6 51.0 1.0
OE2 A:NLG1260 3.0 16.5 1.0
N A:GLY45 3.5 23.2 1.0
F3 A:ALF1261 3.6 60.6 1.0
O3A A:ADP1259 3.7 54.0 1.0
O A:HOH2208 3.8 35.6 1.0
CA A:GLY45 3.8 26.7 1.0
PB A:ADP1259 3.8 53.0 1.0
N A:GLY11 4.0 23.8 1.0
CD A:NLG1260 4.1 14.7 1.0
O A:HOH2050 4.2 40.0 1.0
OE1 A:NLG1260 4.5 14.9 1.0
CA A:GLY11 4.5 24.4 1.0
N A:CYS46 4.5 29.9 1.0
O1B A:ADP1259 4.6 52.8 1.0
N A:GLY44 4.6 18.8 1.0
C A:GLY45 4.6 28.6 1.0
C A:GLY44 4.7 20.9 1.0
MG A:MG1262 4.7 55.3 1.0
PA A:ADP1259 4.8 54.8 1.0
O2B A:ADP1259 4.9 53.4 1.0
O2A A:ADP1259 4.9 55.5 1.0
O A:HOH2210 4.9 19.2 1.0
O1A A:ADP1259 5.0 55.1 1.0

Reference:

F.Gil-Ortiz, S.Ramon-Maiques, I.Fita, V.Rubio. The Course of Phosphorus in the Reaction of N-Acetyl-L-Glutamate Kinase, Determined From the Structures of Crystalline Complexes, Including A Complex with An Alf(4)(-) Transition State Mimic J.Mol.Biol. V. 331 231 2003.
ISSN: ISSN 0022-2836
PubMed: 12875848
DOI: 10.1016/S0022-2836(03)00716-2
Page generated: Wed Jul 31 12:17:00 2024

Last articles

Zn in 9J0N
Zn in 9J0O
Zn in 9J0P
Zn in 9FJX
Zn in 9EKB
Zn in 9C0F
Zn in 9CAH
Zn in 9CH0
Zn in 9CH3
Zn in 9CH1
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy