Fluorine in PDB 1owz: T4 Lysozyme Cavity Mutant L99A/M102Q Bound with 4- Fluorophenethyl Alcohol

Enzymatic activity of T4 Lysozyme Cavity Mutant L99A/M102Q Bound with 4- Fluorophenethyl Alcohol

All present enzymatic activity of T4 Lysozyme Cavity Mutant L99A/M102Q Bound with 4- Fluorophenethyl Alcohol:
3.2.1.17;

Protein crystallography data

The structure of T4 Lysozyme Cavity Mutant L99A/M102Q Bound with 4- Fluorophenethyl Alcohol, PDB code: 1owz was solved by B.Q.Wei, W.A.Baase, L.H.Weaver, B.W.Matthews, B.K.Shoichet, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

*Resolution Low / High (Å)*	13.00 / 1.90
*Space group*	P 3₂ 2 1
*Cell size a, b, c (Å), α, β, γ (°)*	60.800, 60.800, 97.200, 90.00, 90.00, 120.00
*R / R_free (%)*	n/a / n/a

Other elements in 1owz:

The structure of T4 Lysozyme Cavity Mutant L99A/M102Q Bound with 4- Fluorophenethyl Alcohol also contains other interesting chemical elements:

Chlorine

(Cl)

2 atoms

Fluorine Binding Sites:

The binding sites of Fluorine atom in the T4 Lysozyme Cavity Mutant L99A/M102Q Bound with 4- Fluorophenethyl Alcohol (pdb code 1owz). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the T4 Lysozyme Cavity Mutant L99A/M102Q Bound with 4- Fluorophenethyl Alcohol, PDB code: 1owz:

Fluorine binding site 1 out of 1 in 1owz

Go back to

Fluorine Binding Sites List in 1owz

Fluorine binding site 1 out of 1 in the T4 Lysozyme Cavity Mutant L99A/M102Q Bound with 4- Fluorophenethyl Alcohol

Mono view

Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of T4 Lysozyme Cavity Mutant L99A/M102Q Bound with 4- Fluorophenethyl Alcohol within 5.0Å range:

probe	atom	residue	distance (Å)	B	Occ
A:F409 b:54.6 occ:1.00	F8	A:4FA409	0.0	54.6	1.0
	C7	A:4FA409	1.3	17.4	1.0
	C6	A:4FA409	2.4	22.1	1.0
	C5	A:4FA409	2.4	29.6	1.0
	CG2	A:ILE78	3.2	10.8	1.0
	CG1	A:ILE78	3.4	4.9	1.0
	CB	A:TYR88	3.6	8.3	1.0
	C3	A:4FA409	3.6	21.6	1.0
	C2	A:4FA409	3.6	10.3	1.0
	CB	A:LEU84	3.7	14.8	1.0
	O	A:LEU84	3.8	15.8	1.0
	CD1	A:TYR88	3.8	10.1	1.0
	CD1	A:ILE78	3.8	15.2	1.0
	CB	A:ILE78	4.0	11.3	1.0
	CG	A:TYR88	4.0	12.2	1.0
	C	A:LEU84	4.1	19.7	1.0
	C1	A:4FA409	4.1	17.9	1.0
	CB	A:ALA99	4.2	10.5	1.0
	CA	A:LEU84	4.2	17.2	1.0
	CD2	A:LEU84	4.3	25.8	1.0
	CG	A:LEU84	4.3	26.5	1.0
	CA	A:TYR88	4.3	7.7	1.0
	N	A:TYR88	4.4	7.9	1.0
	CD1	A:LEU84	4.4	19.8	1.0
	CA	A:ILE78	4.8	15.2	1.0
	N	A:LYS85	4.9	15.1	1.0
	CE1	A:TYR88	4.9	15.1	1.0

Reference:

B.Q.Wei, L.H.Weaver, A.M.Ferrari, B.W.Matthews, B.K.Shoichet. Testing A Flexible-Receptor Docking Algorithm in A Model Binding Site J.Mol.Biol. V. 337 1161 2004.
ISSN: ISSN 0022-2836
PubMed: 15046985
DOI: 10.1016/J.JMB.2004.02.015

Page generated: Wed Jul 31 12:18:54 2024

Last articles

Zn in 9JYW
Zn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW

	© Copyright 2008-2020 by atomistry.com
Home \| Site Map \| Copyright \| Contact us \| Privacy