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Atomistry » Fluorine » PDB 1o5g-1q6m » 1pwl | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 1o5g-1q6m » 1pwl » |
Fluorine in PDB 1pwl: Crystal Structure of Human Aldose Reductase Complexed with Nadp and MinalrestatEnzymatic activity of Crystal Structure of Human Aldose Reductase Complexed with Nadp and Minalrestat
All present enzymatic activity of Crystal Structure of Human Aldose Reductase Complexed with Nadp and Minalrestat:
1.1.1.21; Protein crystallography data
The structure of Crystal Structure of Human Aldose Reductase Complexed with Nadp and Minalrestat, PDB code: 1pwl
was solved by
O.El-Kabbani,
C.Darmanin,
T.R.Schneider,
I.Hazemann,
F.Ruiz,
M.Oka,
A.Joachimiak,
C.Schulze-Briese,
T.Tomizaki,
A.Mitschler,
A.Podjarny,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 1pwl:
The structure of Crystal Structure of Human Aldose Reductase Complexed with Nadp and Minalrestat also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of Human Aldose Reductase Complexed with Nadp and Minalrestat
(pdb code 1pwl). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the Crystal Structure of Human Aldose Reductase Complexed with Nadp and Minalrestat, PDB code: 1pwl: Jump to Fluorine binding site number: 1; 2; Fluorine binding site 1 out of 2 in 1pwlGo back to Fluorine Binding Sites List in 1pwl
Fluorine binding site 1 out
of 2 in the Crystal Structure of Human Aldose Reductase Complexed with Nadp and Minalrestat
Mono view Stereo pair view
Fluorine binding site 2 out of 2 in 1pwlGo back to Fluorine Binding Sites List in 1pwl
Fluorine binding site 2 out
of 2 in the Crystal Structure of Human Aldose Reductase Complexed with Nadp and Minalrestat
Mono view Stereo pair view
Reference:
O.El-Kabbani,
C.Darmanin,
T.R.Schneider,
I.Hazemann,
F.Ruiz,
M.Oka,
A.Joachimiak,
C.Schulze-Briese,
T.Tomizaki,
A.Mitschler,
A.Podjarny.
Ultrahigh Resolution Drug Design. II. Atomic Resolution Structures of Human Aldose Reductase Holoenzyme Complexed with Fidarestat and Minalrestat: Implications For the Binding of Cyclic Imide Inhibitors Proteins V. 55 805 2004.
Page generated: Sun Dec 13 11:32:00 2020
ISSN: ISSN 0887-3585 PubMed: 15146479 DOI: 10.1002/PROT.20001 |
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