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Atomistry » Fluorine » PDB 1o5g-1q6m » 1pxh | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 1o5g-1q6m » 1pxh » |
Fluorine in PDB 1pxh: Crystal Structure of Protein Tyrosine Phosphatase 1B with Potent and Selective Bidentate Inhibitor Compound 2Enzymatic activity of Crystal Structure of Protein Tyrosine Phosphatase 1B with Potent and Selective Bidentate Inhibitor Compound 2
All present enzymatic activity of Crystal Structure of Protein Tyrosine Phosphatase 1B with Potent and Selective Bidentate Inhibitor Compound 2:
3.1.3.48; Protein crystallography data
The structure of Crystal Structure of Protein Tyrosine Phosphatase 1B with Potent and Selective Bidentate Inhibitor Compound 2, PDB code: 1pxh
was solved by
J.P.Sun,
A.Fedorov,
S.Y.Lee,
X.L.Guo,
K.Shen,
D.S.Lawrence,
S.C.Almo,
Z.Y.Zhang,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 1pxh:
The structure of Crystal Structure of Protein Tyrosine Phosphatase 1B with Potent and Selective Bidentate Inhibitor Compound 2 also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of Protein Tyrosine Phosphatase 1B with Potent and Selective Bidentate Inhibitor Compound 2
(pdb code 1pxh). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 4 binding sites of Fluorine where determined in the Crystal Structure of Protein Tyrosine Phosphatase 1B with Potent and Selective Bidentate Inhibitor Compound 2, PDB code: 1pxh: Jump to Fluorine binding site number: 1; 2; 3; 4; Fluorine binding site 1 out of 4 in 1pxhGo back to Fluorine Binding Sites List in 1pxh
Fluorine binding site 1 out
of 4 in the Crystal Structure of Protein Tyrosine Phosphatase 1B with Potent and Selective Bidentate Inhibitor Compound 2
Mono view Stereo pair view
Fluorine binding site 2 out of 4 in 1pxhGo back to Fluorine Binding Sites List in 1pxh
Fluorine binding site 2 out
of 4 in the Crystal Structure of Protein Tyrosine Phosphatase 1B with Potent and Selective Bidentate Inhibitor Compound 2
Mono view Stereo pair view
Fluorine binding site 3 out of 4 in 1pxhGo back to Fluorine Binding Sites List in 1pxh
Fluorine binding site 3 out
of 4 in the Crystal Structure of Protein Tyrosine Phosphatase 1B with Potent and Selective Bidentate Inhibitor Compound 2
Mono view Stereo pair view
Fluorine binding site 4 out of 4 in 1pxhGo back to Fluorine Binding Sites List in 1pxh
Fluorine binding site 4 out
of 4 in the Crystal Structure of Protein Tyrosine Phosphatase 1B with Potent and Selective Bidentate Inhibitor Compound 2
Mono view Stereo pair view
Reference:
J.P.Sun,
A.A.Fedorov,
S.Y.Lee,
X.L.Guo,
K.Shen,
D.S.Lawrence,
S.C.Almo,
Z.Y.Zhang.
Crystal Structure of PTP1B Complexed with A Potent and Selective Bidentate Inhibitor. J.Biol.Chem. V. 278 12406 2003.
Page generated: Wed Jul 31 12:22:27 2024
ISSN: ISSN 0021-9258 PubMed: 12547827 DOI: 10.1074/JBC.M212491200 |
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