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Atomistry » Fluorine » PDB 1q6n-1rrx » 1q6p | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 1q6n-1rrx » 1q6p » |
Fluorine in PDB 1q6p: The Structure of Phosphotyrosine Phosphatase 1B in Complex with Compound 6Enzymatic activity of The Structure of Phosphotyrosine Phosphatase 1B in Complex with Compound 6
All present enzymatic activity of The Structure of Phosphotyrosine Phosphatase 1B in Complex with Compound 6:
3.1.3.48; Protein crystallography data
The structure of The Structure of Phosphotyrosine Phosphatase 1B in Complex with Compound 6, PDB code: 1q6p
was solved by
G.Scapin,
S.B.Patel,
J.W.Becker,
Q.Wang,
C.Desponts,
D.Waddleton,
K.Skorey,
W.Cromlish,
C.Bayly,
M.Therien,
J.Y.Gauthier,
C.S.Li,
C.K.Lau,
C.Ramachandran,
B.P.Kennedy,
E.Asante-Appiah,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 1q6p:
The structure of The Structure of Phosphotyrosine Phosphatase 1B in Complex with Compound 6 also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the The Structure of Phosphotyrosine Phosphatase 1B in Complex with Compound 6
(pdb code 1q6p). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 4 binding sites of Fluorine where determined in the The Structure of Phosphotyrosine Phosphatase 1B in Complex with Compound 6, PDB code: 1q6p: Jump to Fluorine binding site number: 1; 2; 3; 4; Fluorine binding site 1 out of 4 in 1q6pGo back to Fluorine Binding Sites List in 1q6p
Fluorine binding site 1 out
of 4 in the The Structure of Phosphotyrosine Phosphatase 1B in Complex with Compound 6
Mono view Stereo pair view
Fluorine binding site 2 out of 4 in 1q6pGo back to Fluorine Binding Sites List in 1q6p
Fluorine binding site 2 out
of 4 in the The Structure of Phosphotyrosine Phosphatase 1B in Complex with Compound 6
Mono view Stereo pair view
Fluorine binding site 3 out of 4 in 1q6pGo back to Fluorine Binding Sites List in 1q6p
Fluorine binding site 3 out
of 4 in the The Structure of Phosphotyrosine Phosphatase 1B in Complex with Compound 6
Mono view Stereo pair view
Fluorine binding site 4 out of 4 in 1q6pGo back to Fluorine Binding Sites List in 1q6p
Fluorine binding site 4 out
of 4 in the The Structure of Phosphotyrosine Phosphatase 1B in Complex with Compound 6
Mono view Stereo pair view
Reference:
G.Scapin,
S.B.Patel,
J.W.Becker,
Q.Wang,
C.Desponts,
D.Waddleton,
K.Skorey,
W.Cromlish,
C.Bayly,
M.Therien,
J.Y.Gauthier,
C.S.Li,
C.K.Lau,
C.Ramachandran,
B.P.Kennedy,
E.Asante-Appiah.
The Structural Basis For the Selectivity of Benzotriazole Inhibitors of PTP1B Biochemistry V. 42 11451 2003.
Page generated: Wed Jul 31 12:32:11 2024
ISSN: ISSN 0006-2960 PubMed: 14516196 DOI: 10.1021/BI035098J |
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