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Atomistry » Fluorine » PDB 1q6n-1rrx » 1q6t | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 1q6n-1rrx » 1q6t » |
Fluorine in PDB 1q6t: The Structure of Phosphotyrosine Phosphatase 1B in Complex with Compound 11Enzymatic activity of The Structure of Phosphotyrosine Phosphatase 1B in Complex with Compound 11
All present enzymatic activity of The Structure of Phosphotyrosine Phosphatase 1B in Complex with Compound 11:
3.1.3.48; Protein crystallography data
The structure of The Structure of Phosphotyrosine Phosphatase 1B in Complex with Compound 11, PDB code: 1q6t
was solved by
G.Scapin,
S.B.Patel,
J.W.Becker,
Q.Wang,
C.Desponts,
D.Waddleton,
K.Skorey,
W.Cromlish,
C.Bayly,
M.Therien,
J.Y.Gauthier,
C.S.Li,
C.K.Lau,
C.Ramachandran,
B.P.Kennedy,
E.Asante-Appiah,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 1q6t:
The structure of The Structure of Phosphotyrosine Phosphatase 1B in Complex with Compound 11 also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the The Structure of Phosphotyrosine Phosphatase 1B in Complex with Compound 11
(pdb code 1q6t). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 4 binding sites of Fluorine where determined in the The Structure of Phosphotyrosine Phosphatase 1B in Complex with Compound 11, PDB code: 1q6t: Jump to Fluorine binding site number: 1; 2; 3; 4; Fluorine binding site 1 out of 4 in 1q6tGo back to Fluorine Binding Sites List in 1q6t
Fluorine binding site 1 out
of 4 in the The Structure of Phosphotyrosine Phosphatase 1B in Complex with Compound 11
Mono view Stereo pair view
Fluorine binding site 2 out of 4 in 1q6tGo back to Fluorine Binding Sites List in 1q6t
Fluorine binding site 2 out
of 4 in the The Structure of Phosphotyrosine Phosphatase 1B in Complex with Compound 11
Mono view Stereo pair view
Fluorine binding site 3 out of 4 in 1q6tGo back to Fluorine Binding Sites List in 1q6t
Fluorine binding site 3 out
of 4 in the The Structure of Phosphotyrosine Phosphatase 1B in Complex with Compound 11
Mono view Stereo pair view
Fluorine binding site 4 out of 4 in 1q6tGo back to Fluorine Binding Sites List in 1q6t
Fluorine binding site 4 out
of 4 in the The Structure of Phosphotyrosine Phosphatase 1B in Complex with Compound 11
Mono view Stereo pair view
Reference:
G.Scapin,
S.B.Patel,
J.W.Becker,
Q.Wang,
C.Desponts,
D.Waddleton,
K.Skorey,
W.Cromlish,
C.Bayly,
M.Therien,
J.Y.Gauthier,
C.S.Li,
C.K.Lau,
C.Ramachandran,
B.P.Kennedy,
E.Asante-Appiah.
The Structural Basis For the Selectivity of Benzotriazole Inhibitors of PTP1B Biochemistry V. 42 11451 2003.
Page generated: Sun Dec 13 11:32:09 2020
ISSN: ISSN 0006-2960 PubMed: 14516196 DOI: 10.1021/BI035098J |
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