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Fluorine in PDB 1rxc: E. Coli Uridine Phosphorylase: 5-Fluorouracil Ribose-1-Phosphate Complex
Enzymatic activity of E. Coli Uridine Phosphorylase: 5-Fluorouracil Ribose-1-Phosphate Complex
All present enzymatic activity of E. Coli Uridine Phosphorylase: 5-Fluorouracil Ribose-1-Phosphate Complex:
2.4.2.3;
2.4.2.3;
Protein crystallography data
The structure of E. Coli Uridine Phosphorylase: 5-Fluorouracil Ribose-1-Phosphate Complex, PDB code: 1rxc
was solved by
T.T.Caradoc-Davies,
S.M.Cutfield,
I.L.Lamont,
J.F.Cutfield,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 16.93 / 2.35 |
| Space group | P 1 21 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 90.188, 191.701, 91.909, 90.00, 118.50, 90.00 |
| R / Rfree (%) | 15 / 20.3 |
Other elements in 1rxc:
The structure of E. Coli Uridine Phosphorylase: 5-Fluorouracil Ribose-1-Phosphate Complex also contains other interesting chemical elements:
| Potassium | (K) | 5 atoms |
Fluorine Binding Sites:
The binding sites of Fluorine atom in the E. Coli Uridine Phosphorylase: 5-Fluorouracil Ribose-1-Phosphate Complex
(pdb code 1rxc). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 9 binding sites of Fluorine where determined in the E. Coli Uridine Phosphorylase: 5-Fluorouracil Ribose-1-Phosphate Complex, PDB code: 1rxc:
Jump to Fluorine binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9;
In total 9 binding sites of Fluorine where determined in the E. Coli Uridine Phosphorylase: 5-Fluorouracil Ribose-1-Phosphate Complex, PDB code: 1rxc:
Jump to Fluorine binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9;
Fluorine binding site 1 out of 9 in 1rxc
Go back to
Fluorine Binding Sites List in 1rxc
Fluorine binding site 1 out
of 9 in the E. Coli Uridine Phosphorylase: 5-Fluorouracil Ribose-1-Phosphate Complex
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 1 of E. Coli Uridine Phosphorylase: 5-Fluorouracil Ribose-1-Phosphate Complex within 5.0Å range:
|
Fluorine binding site 2 out of 9 in 1rxc
Go back to
Fluorine Binding Sites List in 1rxc
Fluorine binding site 2 out
of 9 in the E. Coli Uridine Phosphorylase: 5-Fluorouracil Ribose-1-Phosphate Complex
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 2 of E. Coli Uridine Phosphorylase: 5-Fluorouracil Ribose-1-Phosphate Complex within 5.0Å range:
|
Fluorine binding site 3 out of 9 in 1rxc
Go back to
Fluorine Binding Sites List in 1rxc
Fluorine binding site 3 out
of 9 in the E. Coli Uridine Phosphorylase: 5-Fluorouracil Ribose-1-Phosphate Complex
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 3 of E. Coli Uridine Phosphorylase: 5-Fluorouracil Ribose-1-Phosphate Complex within 5.0Å range:
|
Fluorine binding site 4 out of 9 in 1rxc
Go back to
Fluorine Binding Sites List in 1rxc
Fluorine binding site 4 out
of 9 in the E. Coli Uridine Phosphorylase: 5-Fluorouracil Ribose-1-Phosphate Complex
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 4 of E. Coli Uridine Phosphorylase: 5-Fluorouracil Ribose-1-Phosphate Complex within 5.0Å range:
|
Fluorine binding site 5 out of 9 in 1rxc
Go back to
Fluorine Binding Sites List in 1rxc
Fluorine binding site 5 out
of 9 in the E. Coli Uridine Phosphorylase: 5-Fluorouracil Ribose-1-Phosphate Complex
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 5 of E. Coli Uridine Phosphorylase: 5-Fluorouracil Ribose-1-Phosphate Complex within 5.0Å range:
|
Fluorine binding site 6 out of 9 in 1rxc
Go back to
Fluorine Binding Sites List in 1rxc
Fluorine binding site 6 out
of 9 in the E. Coli Uridine Phosphorylase: 5-Fluorouracil Ribose-1-Phosphate Complex
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 6 of E. Coli Uridine Phosphorylase: 5-Fluorouracil Ribose-1-Phosphate Complex within 5.0Å range:
|
Fluorine binding site 7 out of 9 in 1rxc
Go back to
Fluorine Binding Sites List in 1rxc
Fluorine binding site 7 out
of 9 in the E. Coli Uridine Phosphorylase: 5-Fluorouracil Ribose-1-Phosphate Complex
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 7 of E. Coli Uridine Phosphorylase: 5-Fluorouracil Ribose-1-Phosphate Complex within 5.0Å range:
|
Fluorine binding site 8 out of 9 in 1rxc
Go back to
Fluorine Binding Sites List in 1rxc
Fluorine binding site 8 out
of 9 in the E. Coli Uridine Phosphorylase: 5-Fluorouracil Ribose-1-Phosphate Complex
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 8 of E. Coli Uridine Phosphorylase: 5-Fluorouracil Ribose-1-Phosphate Complex within 5.0Å range:
|
Fluorine binding site 9 out of 9 in 1rxc
Go back to
Fluorine Binding Sites List in 1rxc
Fluorine binding site 9 out
of 9 in the E. Coli Uridine Phosphorylase: 5-Fluorouracil Ribose-1-Phosphate Complex
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 9 of E. Coli Uridine Phosphorylase: 5-Fluorouracil Ribose-1-Phosphate Complex within 5.0Å range:
|
Reference:
T.T.Caradoc-Davies,
S.M.Cutfield,
I.L.Lamont,
J.F.Cutfield.
Crystal Structures of Escherichia Coli Uridine Phosphorylase in Two Native and Three Complexed Forms Reveal Basis of Substrate Specificity, Induced Conformational Changes and Influence of Potassium J.Mol.Biol. V. 337 337 2004.
ISSN: ISSN 0022-2836
PubMed: 15003451
DOI: 10.1016/J.JMB.2004.01.039
Page generated: Sun Dec 13 11:32:42 2020
ISSN: ISSN 0022-2836
PubMed: 15003451
DOI: 10.1016/J.JMB.2004.01.039
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