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Atomistry » Fluorine » PDB 1rw8-1uda » 1s9j | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 1rw8-1uda » 1s9j » |
Fluorine in PDB 1s9j: X-Ray Structure of the Human Mitogen-Activated Protein Kinase Kinase 1 (MEK1) in A Complex with Ligand and MgatpEnzymatic activity of X-Ray Structure of the Human Mitogen-Activated Protein Kinase Kinase 1 (MEK1) in A Complex with Ligand and Mgatp
All present enzymatic activity of X-Ray Structure of the Human Mitogen-Activated Protein Kinase Kinase 1 (MEK1) in A Complex with Ligand and Mgatp:
2.7.1.37; Protein crystallography data
The structure of X-Ray Structure of the Human Mitogen-Activated Protein Kinase Kinase 1 (MEK1) in A Complex with Ligand and Mgatp, PDB code: 1s9j
was solved by
J.F.Ohren,
H.Chen,
A.Pavlovsky,
C.Whitehead,
C.Yan,
P.Mcconnell,
A.Delaney,
D.T.Dudley,
J.Sebolt-Leopold,
C.A.Hasemann,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 1s9j:
The structure of X-Ray Structure of the Human Mitogen-Activated Protein Kinase Kinase 1 (MEK1) in A Complex with Ligand and Mgatp also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the X-Ray Structure of the Human Mitogen-Activated Protein Kinase Kinase 1 (MEK1) in A Complex with Ligand and Mgatp
(pdb code 1s9j). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 3 binding sites of Fluorine where determined in the X-Ray Structure of the Human Mitogen-Activated Protein Kinase Kinase 1 (MEK1) in A Complex with Ligand and Mgatp, PDB code: 1s9j: Jump to Fluorine binding site number: 1; 2; 3; Fluorine binding site 1 out of 3 in 1s9jGo back to Fluorine Binding Sites List in 1s9j
Fluorine binding site 1 out
of 3 in the X-Ray Structure of the Human Mitogen-Activated Protein Kinase Kinase 1 (MEK1) in A Complex with Ligand and Mgatp
Mono view Stereo pair view
Fluorine binding site 2 out of 3 in 1s9jGo back to Fluorine Binding Sites List in 1s9j
Fluorine binding site 2 out
of 3 in the X-Ray Structure of the Human Mitogen-Activated Protein Kinase Kinase 1 (MEK1) in A Complex with Ligand and Mgatp
Mono view Stereo pair view
Fluorine binding site 3 out of 3 in 1s9jGo back to Fluorine Binding Sites List in 1s9j
Fluorine binding site 3 out
of 3 in the X-Ray Structure of the Human Mitogen-Activated Protein Kinase Kinase 1 (MEK1) in A Complex with Ligand and Mgatp
Mono view Stereo pair view
Reference:
J.F.Ohren,
H.Chen,
A.Pavlovsky,
C.Whitehead,
E.Zhang,
P.Kuffa,
C.Yan,
P.Mcconnell,
C.Spessard,
C.Banotai,
W.T.Mueller,
A.Delaney,
C.Omer,
J.Sebolt-Leopold,
D.T.Dudley,
I.K.Leung,
C.Flamme,
J.Warmus,
M.Kaufman,
S.Barrett,
H.Tecle,
C.A.Hasemann.
Structures of Human Map Kinase Kinase 1 (MEK1) and MEK2 Describe Novel Noncompetitive Kinase Inhibition. Nat.Struct.Mol.Biol. V. 11 1192 2004.
Page generated: Wed Jul 31 12:50:13 2024
ISSN: ISSN 1545-9993 PubMed: 15543157 DOI: 10.1038/NSMB859 |
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