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Atomistry » Fluorine » PDB 1rw8-1uda » 1tqf » |
Fluorine in PDB 1tqf: Crystal Structure of Human Beta Secretase Complexed with InhibitorEnzymatic activity of Crystal Structure of Human Beta Secretase Complexed with Inhibitor
All present enzymatic activity of Crystal Structure of Human Beta Secretase Complexed with Inhibitor:
3.4.23.46; Protein crystallography data
The structure of Crystal Structure of Human Beta Secretase Complexed with Inhibitor, PDB code: 1tqf
was solved by
S.Munshi,
Z.Chen,
L.Kuo,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of Human Beta Secretase Complexed with Inhibitor
(pdb code 1tqf). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Crystal Structure of Human Beta Secretase Complexed with Inhibitor, PDB code: 1tqf: Fluorine binding site 1 out of 1 in 1tqfGo back to Fluorine Binding Sites List in 1tqf
Fluorine binding site 1 out
of 1 in the Crystal Structure of Human Beta Secretase Complexed with Inhibitor
Mono view Stereo pair view
Reference:
C.A.Coburn,
S.J.Stachel,
Y.M.Li,
D.M.Rush,
T.G.Steele,
E.Chen-Dodson,
M.K.Holloway,
M.Xu,
Q.Huang,
M.T.Lai,
J.Dimuzio,
M.C.Crouthamel,
X.P.Shi,
V.Sardana,
Z.Chen,
S.Munshi,
L.Kuo,
G.M.Makara,
D.A.Annis,
P.K.Tadikonda,
H.M.Nash,
J.P.Vacca,
T.Wang.
Identification of A Small Molecule Nonpeptide Active Site Beta-Secretase Inhibitor That Displays A Nontraditional Binding Mode For Aspartyl Proteases. J.Med.Chem. V. 47 6117 2004.
Page generated: Sun Dec 13 11:33:03 2020
ISSN: ISSN 0022-2623 PubMed: 15566281 DOI: 10.1021/JM049388P |
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