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Atomistry » Fluorine » PDB 1w6j-1xz1 » 1xl5 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 1w6j-1xz1 » 1xl5 » |
Fluorine in PDB 1xl5: Hiv-1 Protease in Complex with AmidhyroxysulfoneEnzymatic activity of Hiv-1 Protease in Complex with Amidhyroxysulfone
All present enzymatic activity of Hiv-1 Protease in Complex with Amidhyroxysulfone:
3.4.23.16; Protein crystallography data
The structure of Hiv-1 Protease in Complex with Amidhyroxysulfone, PDB code: 1xl5
was solved by
J.Boettcher,
E.Specker,
A.Heine,
G.Klebe,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 1xl5:
The structure of Hiv-1 Protease in Complex with Amidhyroxysulfone also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Hiv-1 Protease in Complex with Amidhyroxysulfone
(pdb code 1xl5). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Hiv-1 Protease in Complex with Amidhyroxysulfone, PDB code: 1xl5: Fluorine binding site 1 out of 1 in 1xl5Go back to![]() ![]()
Fluorine binding site 1 out
of 1 in the Hiv-1 Protease in Complex with Amidhyroxysulfone
![]() Mono view ![]() Stereo pair view
Reference:
E.Specker,
J.Boettcher,
H.Lilie,
A.Heine,
A.Schoop,
G.Muller,
N.Griebenow,
G.Klebe.
An Old Target Revisited: Two New Privileged Skeletons and An Unexpected Binding Mode For Hiv-Protease Inhibitors Angew.Chem.Int.Ed.Engl. V. 44 3140 2005.
Page generated: Mon Jul 14 12:21:14 2025
ISSN: ESSN 0570-0833 PubMed: 15822136 DOI: 10.1002/ANIE.200462643 |
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