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Atomistry » Fluorine » PDB 1xz3-1zzr » 1ygc » |
Fluorine in PDB 1ygc: Short Factor Viia with A Small Molecule InhibitorEnzymatic activity of Short Factor Viia with A Small Molecule Inhibitor
All present enzymatic activity of Short Factor Viia with A Small Molecule Inhibitor:
3.4.21.21; Protein crystallography data
The structure of Short Factor Viia with A Small Molecule Inhibitor, PDB code: 1ygc
was solved by
A.G.Olivero,
C.Eigenbrot,
R.Goldsmith,
K.Robarge,
D.R.Artis,
J.Flygare,
T.Rawson,
C.Refino,
S.Bunting,
D.Kirchhofer,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 1ygc:
The structure of Short Factor Viia with A Small Molecule Inhibitor also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Short Factor Viia with A Small Molecule Inhibitor
(pdb code 1ygc). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Short Factor Viia with A Small Molecule Inhibitor, PDB code: 1ygc: Fluorine binding site 1 out of 1 in 1ygcGo back to Fluorine Binding Sites List in 1ygc
Fluorine binding site 1 out
of 1 in the Short Factor Viia with A Small Molecule Inhibitor
Mono view Stereo pair view
Reference:
A.G.Olivero,
C.Eigenbrot,
R.Goldsmith,
K.Robarge,
D.R.Artis,
J.Flygare,
T.Rawson,
D.P.Sutherlin,
S.Kadkhodayan,
M.Beresini,
L.O.Elliott,
G.G.Deguzman,
D.W.Banner,
M.Ultsch,
U.Marzec,
S.R.Hanson,
C.Refino,
S.Bunting,
D.Kirchhofer.
A Selective, Slow Binding Inhibitor of Factor Viia Binds to A Nonstandard Active Site Conformation and Attenuates Thrombus Formation in Vivo. J.Biol.Chem. V. 280 9160 2005.
Page generated: Sun Dec 13 11:34:14 2020
ISSN: ISSN 0021-9258 PubMed: 15632123 DOI: 10.1074/JBC.M409068200 |
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