Fluorine in PDB 1ysx: Solution Structure of Domain 3 From Human Serum Albumin Complexed to An Anti-Apoptotic Ligand Directed Against Bcl- Xl and Bcl-2

The binding sites of Fluorine atom in the Solution Structure of Domain 3 From Human Serum Albumin Complexed to An Anti-Apoptotic Ligand Directed Against Bcl- Xl and Bcl-2 (pdb code 1ysx). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Solution Structure of Domain 3 From Human Serum Albumin Complexed to An Anti-Apoptotic Ligand Directed Against Bcl- Xl and Bcl-2, PDB code: 1ysx:

Fluorine binding site 1 out of 1 in the Solution Structure of Domain 3 From Human Serum Albumin Complexed to An Anti-Apoptotic Ligand Directed Against Bcl- Xl and Bcl-2


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Solution Structure of Domain 3 From Human Serum Albumin Complexed to An Anti-Apoptotic Ligand Directed Against Bcl- Xl and Bcl-2 within 5.0Å range: probe atom residue distance (Å) B Occ A:F1000 b:20.0 occ:1.00 F35 A:4EB1000 0.0 20.0 1.0 C34 A:4EB1000 1.4 20.0 1.0 C36 A:4EB1000 2.4 20.0 1.0 C33 A:4EB1000 2.4 20.0 1.0 H24 A:4EB1000 2.6 20.0 1.0 H25 A:4EB1000 2.6 20.0 1.0 HG A:CYS392 3.1 0.0 1.0 SG A:CYS392 3.3 41.3 1.0 HA A:CYS392 3.4 0.0 1.0 C32 A:4EB1000 3.7 20.0 1.0 C37 A:4EB1000 3.7 20.0 1.0 SG A:CYS437 3.8 44.3 1.0 HA2 A:GLY434 3.8 0.0 1.0 HG A:CYS437 4.0 0.0 1.0 C31 A:4EB1000 4.2 20.0 1.0 CA A:CYS392 4.2 55.1 1.0 CB A:CYS392 4.4 55.1 1.0 N A:CYS392 4.4 55.1 1.0 HB2 A:ASN391 4.5 0.0 1.0 H23 A:4EB1000 4.5 20.0 1.0 H26 A:4EB1000 4.5 20.0 1.0 HG21 A:ILE388 4.6 0.0 1.0 HB3 A:ASN391 4.6 0.0 1.0 OH A:TYR452 4.6 82.2 1.0 HG11 A:VAL433 4.7 0.0 1.0 H A:CYS392 4.7 0.0 1.0 HG12 A:VAL433 4.7 0.0 1.0 CA A:GLY434 4.8 37.6 1.0 HH A:TYR452 4.8 0.0 1.0 C A:ASN391 4.8 51.0 1.0 HB3 A:PHE395 4.8 0.0 1.0 O A:ILE388 4.9 46.1 1.0 HA3 A:GLY434 5.0 0.0 1.0 O A:ASN391 5.0 51.0 1.0

T.Oltersdorf, S.W.Elmore, A.R.Shoemaker, R.C.Armstrong, D.J.Augeri, B.A.Belli, M.Bruncko, T.L.Deckwerth, J.Dinges, P.J.Hajduk, M.K.Joseph, S.Kitada, S.J.Korsmeyer, A.R.Kunzer, A.Letai, C.Li, M.J.Mitten, D.G.Nettesheim, S.Ng, P.M.Nimmer, J.M.O'connor, A.Oleksijew, A.M.Petros, J.C.Reed, W.Shen, S.K.Tahir, C.B.Thompson, K.J.Tomaselli, B.Wang, M.D.Wendt, H.Zhang, S.W.Fesik, S.H.Rosenberg. An Inhibitor of Bcl-2 Family Proteins Induces Regression of Solid Tumours Nature V. 435 677 2005.
ISSN: ISSN 0028-0836
PubMed: 15902208
DOI: 10.1038/NATURE03579