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Atomistry » Fluorine » PDB 1xz3-1zzr » 1yw9 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 1xz3-1zzr » 1yw9 » |
Fluorine in PDB 1yw9: H-METAP2 Complexed with A849519Enzymatic activity of H-METAP2 Complexed with A849519
All present enzymatic activity of H-METAP2 Complexed with A849519:
3.4.11.18; Protein crystallography data
The structure of H-METAP2 Complexed with A849519, PDB code: 1yw9
was solved by
C.H.Park,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 1yw9:
The structure of H-METAP2 Complexed with A849519 also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the H-METAP2 Complexed with A849519
(pdb code 1yw9). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the H-METAP2 Complexed with A849519, PDB code: 1yw9: Fluorine binding site 1 out of 1 in 1yw9Go back to Fluorine Binding Sites List in 1yw9
Fluorine binding site 1 out
of 1 in the H-METAP2 Complexed with A849519
Mono view Stereo pair view
Reference:
G.S.Sheppard,
J.Wang,
M.Kawai,
S.D.Fidanze,
N.Y.Bamaung,
S.A.Erickson,
D.M.Barnes,
J.S.Tedrow,
L.Kolaczkowski,
A.Vasudevan,
D.C.Park,
G.T.Wang,
W.J.Sanders,
R.A.Mantei,
F.Palazzo,
L.Tucker-Garcia,
P.Lou,
Q.Zhang,
C.H.Park,
K.H.Kim,
A.Petros,
E.Olejniczak,
D.Nettesheim,
P.Hajduk,
J.Henkin,
R.Lesniewski,
S.K.Davidsen,
R.L.Bell.
Discovery and Optimization of Anthranilic Acid Sulfonamides As Inhibitors of Methionine Aminopeptidase-2: A Structural Basis For the Reduction of Albumin Binding. J.Med.Chem. V. 49 3832 2006.
Page generated: Sun Dec 13 11:34:21 2020
ISSN: ISSN 0022-2623 PubMed: 16789740 DOI: 10.1021/JM0601001 |
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