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Atomistry » Fluorine » PDB 1xz3-1zzr » 1zz2 » |
Fluorine in PDB 1zz2: Two Classes of P38ALPHA Map Kinase Inhibitors Having A Common Diphenylether Core But Exhibiting Divergent Binding ModesEnzymatic activity of Two Classes of P38ALPHA Map Kinase Inhibitors Having A Common Diphenylether Core But Exhibiting Divergent Binding Modes
All present enzymatic activity of Two Classes of P38ALPHA Map Kinase Inhibitors Having A Common Diphenylether Core But Exhibiting Divergent Binding Modes:
2.7.1.37; Protein crystallography data
The structure of Two Classes of P38ALPHA Map Kinase Inhibitors Having A Common Diphenylether Core But Exhibiting Divergent Binding Modes, PDB code: 1zz2
was solved by
E.L.Michelotti,
K.K.Moffett,
E.B.Springman,
M.Karpusas,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Two Classes of P38ALPHA Map Kinase Inhibitors Having A Common Diphenylether Core But Exhibiting Divergent Binding Modes
(pdb code 1zz2). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Two Classes of P38ALPHA Map Kinase Inhibitors Having A Common Diphenylether Core But Exhibiting Divergent Binding Modes, PDB code: 1zz2: Fluorine binding site 1 out of 1 in 1zz2Go back to![]() ![]()
Fluorine binding site 1 out
of 1 in the Two Classes of P38ALPHA Map Kinase Inhibitors Having A Common Diphenylether Core But Exhibiting Divergent Binding Modes
![]() Mono view ![]() Stereo pair view
Reference:
E.L.Michelotti,
K.K.Moffett,
D.Nguyen,
M.J.Kelly,
R.Shetty,
X.Chai,
K.Northrop,
V.Namboodiri,
B.Campbell,
G.A.Flynn,
T.Fujimoto,
F.P.Hollinger,
M.Bukhtiyarova,
E.B.Springman,
M.Karpusas.
Two Classes of P38ALPHA Map Kinase Inhibitors Having A Common Diphenylether Core But Exhibiting Divergent Binding Modes. Bioorg.Med.Chem.Lett. V. 15 5274 2005.
Page generated: Wed Jul 31 13:40:02 2024
ISSN: ISSN 0960-894X PubMed: 16169718 DOI: 10.1016/J.BMCL.2005.08.038 |
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