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Atomistry » Fluorine » PDB 2a4z-2baq » 2agt » |
Fluorine in PDB 2agt: Aldose Reductase Mutant Leu 300 Pro Complexed with FidarestatEnzymatic activity of Aldose Reductase Mutant Leu 300 Pro Complexed with Fidarestat
All present enzymatic activity of Aldose Reductase Mutant Leu 300 Pro Complexed with Fidarestat:
1.1.1.21; Protein crystallography data
The structure of Aldose Reductase Mutant Leu 300 Pro Complexed with Fidarestat, PDB code: 2agt
was solved by
T.Petrova,
H.Steuber,
I.Hazemann,
A.Cousido-Siah,
A.Mitschler,
R.Chung,
M.Oka,
G.Klebe,
O.El-Kabbani,
A.Joachimiak,
A.Podjarny,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 2agt:
The structure of Aldose Reductase Mutant Leu 300 Pro Complexed with Fidarestat also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Aldose Reductase Mutant Leu 300 Pro Complexed with Fidarestat
(pdb code 2agt). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Aldose Reductase Mutant Leu 300 Pro Complexed with Fidarestat, PDB code: 2agt: Fluorine binding site 1 out of 1 in 2agtGo back to Fluorine Binding Sites List in 2agt
Fluorine binding site 1 out
of 1 in the Aldose Reductase Mutant Leu 300 Pro Complexed with Fidarestat
Mono view Stereo pair view
Reference:
T.Petrova,
H.Steuber,
I.Hazemann,
A.Cousido-Siah,
A.Mitschler,
R.Chung,
M.Oka,
G.Klebe,
O.El-Kabbani,
A.Joachimiak,
A.Podjarny.
Factorizing Selectivity Determinants of Inhibitor Binding Toward Aldose and Aldehyde Reductases: Structural and Thermodynamic Properties of the Aldose Reductase Mutant LEU300PRO-Fidarestat Complex J.Med.Chem. V. 48 5659 2005.
Page generated: Wed Jul 31 13:44:06 2024
ISSN: ISSN 0022-2623 PubMed: 16134934 DOI: 10.1021/JM050424+ |
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