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Fluorine in PDB 2bu2: Crystal Structures of Human Pyruvate Dehydrogenase Kinase 2 Containing Physiological and Synthetic Ligands
Enzymatic activity of Crystal Structures of Human Pyruvate Dehydrogenase Kinase 2 Containing Physiological and Synthetic Ligands
All present enzymatic activity of Crystal Structures of Human Pyruvate Dehydrogenase Kinase 2 Containing Physiological and Synthetic Ligands:
2.7.1.99;
2.7.1.99;
Protein crystallography data
The structure of Crystal Structures of Human Pyruvate Dehydrogenase Kinase 2 Containing Physiological and Synthetic Ligands, PDB code: 2bu2
was solved by
T.R.Knoechel,
A.D.Tucker,
C.M.Robinson,
C.Phillips,
W.Taylor,
P.J.Bungay,
S.A.Kasten,
T.E.Roche,
D.G.Brown,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 30.00 / 2.40 |
| Space group | P 64 |
| Cell size a, b, c (Å), α, β, γ (°) | 108.703, 108.703, 83.855, 90.00, 90.00, 120.00 |
| R / Rfree (%) | n/a / n/a |
Other elements in 2bu2:
The structure of Crystal Structures of Human Pyruvate Dehydrogenase Kinase 2 Containing Physiological and Synthetic Ligands also contains other interesting chemical elements:
| Magnesium | (Mg) | 1 atom |
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structures of Human Pyruvate Dehydrogenase Kinase 2 Containing Physiological and Synthetic Ligands
(pdb code 2bu2). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 3 binding sites of Fluorine where determined in the Crystal Structures of Human Pyruvate Dehydrogenase Kinase 2 Containing Physiological and Synthetic Ligands, PDB code: 2bu2:
Jump to Fluorine binding site number: 1; 2; 3;
In total 3 binding sites of Fluorine where determined in the Crystal Structures of Human Pyruvate Dehydrogenase Kinase 2 Containing Physiological and Synthetic Ligands, PDB code: 2bu2:
Jump to Fluorine binding site number: 1; 2; 3;
Fluorine binding site 1 out of 3 in 2bu2
Go back to
Fluorine Binding Sites List in 2bu2
Fluorine binding site 1 out
of 3 in the Crystal Structures of Human Pyruvate Dehydrogenase Kinase 2 Containing Physiological and Synthetic Ligands
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 1 of Crystal Structures of Human Pyruvate Dehydrogenase Kinase 2 Containing Physiological and Synthetic Ligands within 5.0Å range:
|
Fluorine binding site 2 out of 3 in 2bu2
Go back to
Fluorine Binding Sites List in 2bu2
Fluorine binding site 2 out
of 3 in the Crystal Structures of Human Pyruvate Dehydrogenase Kinase 2 Containing Physiological and Synthetic Ligands
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 2 of Crystal Structures of Human Pyruvate Dehydrogenase Kinase 2 Containing Physiological and Synthetic Ligands within 5.0Å range:
|
Fluorine binding site 3 out of 3 in 2bu2
Go back to
Fluorine Binding Sites List in 2bu2
Fluorine binding site 3 out
of 3 in the Crystal Structures of Human Pyruvate Dehydrogenase Kinase 2 Containing Physiological and Synthetic Ligands
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 3 of Crystal Structures of Human Pyruvate Dehydrogenase Kinase 2 Containing Physiological and Synthetic Ligands within 5.0Å range:
|
Reference:
T.R.Knoechel,
A.D.Tucker,
C.M.Robinson,
C.Phillips,
W.Taylor,
P.J.Bungay,
S.A.Kasten,
T.E.Roche,
D.G.Brown.
Regulatory Roles of the N-Terminal Domain Based on Crystal Structures of Human Pyruvate Dehydrogenase Kinase 2 Containing Physiological and Synthetic Ligands. Biochemistry V. 45 402 2006.
ISSN: ISSN 0006-2960
PubMed: 16401071
DOI: 10.1021/BI051402S
Page generated: Sun Dec 13 11:35:10 2020
ISSN: ISSN 0006-2960
PubMed: 16401071
DOI: 10.1021/BI051402S
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