Fluorine in PDB 2chl: Structure of Casein Kinase 1 Gamma 3

The structure of Structure of Casein Kinase 1 Gamma 3, PDB code: 2chl was solved by G.Bunkoczi, E.Salah, P.Rellos, S.Das, O.Fedorov, P.Savitsky, O.Gileadi, M.Sundstrom, A.Edwards, C.Arrowsmith, E.Ugochukwu, J.Weigelt, F.Vondelft, S.Knapp, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 1.95
Space group	P 31 2 1
Cell size a, b, c (Å), α, β, γ (°)	55.802, 55.802, 219.707, 90.00, 90.00, 120.00
R / Rfree (%)	18.3 / 23.4

The binding sites of Fluorine atom in the Structure of Casein Kinase 1 Gamma 3 (pdb code 2chl). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the Structure of Casein Kinase 1 Gamma 3, PDB code: 2chl:
Jump to Fluorine binding site number: 1; 2;

Fluorine binding site 1 out of 2 in the Structure of Casein Kinase 1 Gamma 3


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Structure of Casein Kinase 1 Gamma 3 within 5.0Å range: probe atom residue distance (Å) B Occ A:F1323 b:23.6 occ:1.00 FAF A:DKI1323 0.0 23.6 1.0 CAU A:DKI1323 1.4 31.4 1.0 CAZ A:DKI1323 2.4 31.3 1.0 CAI A:DKI1323 2.4 19.5 1.0 NAQ A:DKI1323 2.6 28.0 1.0 CG2 A:ILE184 2.9 25.1 1.0 O A:HOH2112 3.3 17.2 1.0 O A:GLU166 3.4 20.6 1.0 CD2 A:LEU169 3.4 20.7 1.0 CAS A:DKI1323 3.4 10.7 1.0 O A:HOH2250 3.6 22.5 1.0 CD1 A:LEU169 3.6 19.4 1.0 CAV A:DKI1323 3.6 31.8 1.0 CAH A:DKI1323 3.7 42.6 1.0 CG A:LEU169 3.9 25.0 1.0 CAJ A:DKI1323 4.2 36.4 1.0 SAE A:DKI1323 4.2 22.1 1.0 NBA A:DKI1323 4.3 16.7 1.0 CB A:ILE184 4.3 29.2 1.0 O A:HOH2026 4.5 21.0 1.0 C A:GLU166 4.5 18.0 1.0 NAP A:DKI1323 4.5 18.0 1.0 OD1 A:ASN167 4.5 15.4 1.0 CG1 A:ILE184 4.6 29.2 1.0 CA A:ASN167 4.6 25.0 1.0 CD1 A:ILE184 4.7 35.0 1.0 FAG A:DKI1323 4.8 25.1 1.0 O A:HOH2059 4.8 30.2 1.0

Fluorine binding site 2 out of 2 in the Structure of Casein Kinase 1 Gamma 3


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Structure of Casein Kinase 1 Gamma 3 within 5.0Å range: probe atom residue distance (Å) B Occ A:F1323 b:25.1 occ:1.00 FAG A:DKI1323 0.0 25.1 1.0 CAV A:DKI1323 1.3 31.8 1.0 CAJ A:DKI1323 2.3 36.4 1.0 CAZ A:DKI1323 2.4 31.3 1.0 NAQ A:DKI1323 2.9 28.0 1.0 CD1 A:LEU57 3.2 19.6 1.0 CB A:LEU57 3.3 22.6 1.0 CAS A:DKI1323 3.3 10.7 1.0 CD2 A:LEU57 3.4 21.1 1.0 CG A:LEU57 3.4 33.3 1.0 SAE A:DKI1323 3.4 22.1 1.0 CZ A:PHE54 3.6 28.1 1.0 CAH A:DKI1323 3.6 42.6 1.0 CAU A:DKI1323 3.7 31.4 1.0 CE2 A:PHE54 3.9 34.9 1.0 O A:HOH2026 4.1 21.0 1.0 CAI A:DKI1323 4.1 19.5 1.0 O A:HOH2009 4.1 40.9 1.0 CE1 A:PHE54 4.2 25.2 1.0 CE A:LYS72 4.4 28.2 1.0 CG A:LYS72 4.4 38.5 1.0 NBA A:DKI1323 4.4 16.7 1.0 CA A:LEU57 4.5 22.1 1.0 CD A:LYS72 4.7 34.7 1.0 CD2 A:PHE54 4.7 19.8 1.0 FAF A:DKI1323 4.8 23.6 1.0 NAP A:DKI1323 4.9 18.0 1.0 N A:LEU57 4.9 22.0 1.0 CD1 A:PHE54 5.0 38.7 1.0

G.Bunkoczi, E.Salah, P.Rellos, S.Das, O.Fedorov, P.Savitsky, O.Gileadi, M.Sundstrom, A.Edwards, C.Arrowsmith, E.Ugochukwu, J.Weigelt, F.Von Delft, S.Knapp. Structure of Casein Kinase 1 Gamma 3 To Be Published.