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Atomistry » Fluorine » PDB 2duz-2fq6 » 2ea4 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 2duz-2fq6 » 2ea4 » |
Fluorine in PDB 2ea4: H-METAP2 Complexed with A797859Enzymatic activity of H-METAP2 Complexed with A797859
All present enzymatic activity of H-METAP2 Complexed with A797859:
3.4.11.18; Protein crystallography data
The structure of H-METAP2 Complexed with A797859, PDB code: 2ea4
was solved by
C.H.Park,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 2ea4:
The structure of H-METAP2 Complexed with A797859 also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the H-METAP2 Complexed with A797859
(pdb code 2ea4). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the H-METAP2 Complexed with A797859, PDB code: 2ea4: Fluorine binding site 1 out of 1 in 2ea4Go back to Fluorine Binding Sites List in 2ea4
Fluorine binding site 1 out
of 1 in the H-METAP2 Complexed with A797859
Mono view Stereo pair view
Reference:
G.T.Wang,
R.A.Mantei,
M.Kawai,
J.S.Tedrow,
D.M.Barnes,
J.Wang,
Q.Zhang,
P.Lou,
L.A.Garcia,
J.Bouska,
M.Yates,
C.Park,
R.A.Judge,
R.Lesniewski,
G.S.Sheppard,
R.L.Bell.
Lead Optimization of Methionine Aminopeptidase-2 (METAP2) Inhibitors Containing Sulfonamides of 5,6-Disubstituted Anthranilic Acids Bioorg.Med.Chem.Lett. V. 17 2817 2007.
Page generated: Sun Dec 13 11:35:43 2020
ISSN: ISSN 0960-894X PubMed: 17350258 DOI: 10.1016/J.BMCL.2007.02.062 |
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