Chemical elements
  Fluorine
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    PDB 16pk-1c8m
    PDB 1c9d-1eau
    PDB 1ec0-1grn
    PDB 1gs4-1j97
    PDB 1jdj-1mu8
    PDB 1mue-1oyt
    PDB 1oz1-1rby
    PDB 1rbz-1tu6
    PDB 1tuy-1w9i
    PDB 1w9j-1yw2
    PDB 1yw9-2ax8
    PDB 2ax9-2dqt
    PDB 2dqu-2ftk
    PDB 2fvd-2hhn
      2fvd
      2fyu
      2fz8
      2fz9
      2fzb
      2fzd
      2fzz
      2g00
      2g07
      2g08
      2g0g
      2g0h
      2g1q
      2g1s
      2g24
      2g6w
      2g71
      2g72
      2g77
      2g7y
      2g83
      2g92
      2gfs
      2gg0
      2gg2
      2gg3
      2gg5
      2gh6
      2giq
      2gj8
      2gj9
      2gja
      2gmv
      2gtm
      2gtn
      2gtp
      2gyd
      2gz7
      2gz8
      2h1h
      2h55
      2h9y
      2hai
      2haw
      2hcy
      2heg
      2hf7
      2hfp
      2hh5
      2hhn
    PDB 2hiw-2izs
    PDB 2j51-2onh
    PDB 2oo8-2pow
    PDB 2pq9-2qzl
    PDB 2qzo-2vev
    PDB 2vew-2wf7
    PDB 2wf8-2xhd
    PDB 2xkk-3ar9
    PDB 3az8-3cej
    PDB 3cem-3dh3
    PDB 3dhf-3el7
    PDB 3el8-3fln
    PDB 3flq-3gc7
    PDB 3gc8-3h7w
    PDB 3h82-3i81
    PDB 3i8d-3jx1
    PDB 3jx2-3ktk
    PDB 3ktu-3lj6
    PDB 3lk9-3mqf
    PDB 3ms4-3nz7
    PDB 3o1g-3p4a
    PDB 3p4b-3ti1
    PDB 3tik-4acx
    PDB 4afe-4fk3
    PDB 4fod-7gch

Fluorine in the structure of Human Aldose Reductase Complexed With Tolrestat At 1.08 A Resolution. (pdb 2fzd)






The binding sites of Fluorine atom in the structure of Human Aldose Reductase Complexed With Tolrestat At 1.08 A Resolution. (pdb code 2fzd). This binding sites where shown with 5.0 Angstroms radius around Fluorine atom.
The 2fzd structure was solved by H.STEUBER, M.ZENTGRAF, C.GERLACH, C.A.SOTRIFFER, A.HEINE, G.KLEBE, with X-Ray Crystallography technique, brief refinement statistics is given in the table below:
Resolution (A)10.0-1.1
Space groupP1211
a (A)49.450
b (A)66.679
c (A)46.060
alpha (°)90.00
beta (°)92.45
gamma (°)90.00
Rfactor (%)11
Rfree (%)13.7


Fluorine Binding Sites:

Fluorine binding site 1 out of 3 in 2fzd


Fluorine binding site 1 out of 3 in 2fzd
Click to enlarge
stereopicture of Fluorine binding site 1 out of 3 in 2fzd
Click to enlarge
Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 1 of Fluorine in the PDB 2fzd. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Fluorine atom, shown by VdW sphere
Residues shown as a stick model or VDW spheres: A: Leu300, A: Ser302, A: Cys303, A: Tol317, A: Hoh487, A: Hoh592, A: Hoh618, A: Hoh635, A: Hoh657,

conact list:


AtomAtomDistance (A)
FO A:Leu3004.68
FCB A:Leu3003.71
FCD1 A:Leu3004.33
FCD2 A:Leu3003.97
FC A:Leu3004.71
FCG A:Leu3004.19
FCA A:Leu3004.34
FN A:Ser3024.92
FCB A:Ser3024.24
FOG A:Ser3022.94
FC A:Ser3024.86
FCA A:Ser3024.92
FN A:Cys3034.70
FCB A:Cys3034.57
FC12 A:Tol3172.92
FC11 A:Tol3172.94
FC1 A:Tol3171.31
FO1 A:Tol3173.74
FF2 A:Tol3172.10
FC2 A:Tol3172.34
FC6 A:Tol3174.90
FC5 A:Tol3174.61
FC7 A:Tol3174.25
FC10 A:Tol3174.24
FC3 A:Tol3173.43
FF3 A:Tol3172.11
FF1 A:Tol3170.00
FO A:Hoh4874.36
FO A:Hoh5924.37
FO A:Hoh6183.71
FO A:Hoh6353.05
FO A:Hoh6573.58

interactive model:


Fluorine binding site 2 out of 3 in 2fzd


Fluorine binding site 2 out of 3 in 2fzd
Click to enlarge
stereopicture of Fluorine binding site 2 out of 3 in 2fzd
Click to enlarge
Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 2 of Fluorine in the PDB 2fzd. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Fluorine atom, shown by VdW sphere
Residues shown as a stick model or VDW spheres: A: Phe115, A: Val130, A: Leu300, A: Ser302, A: Cys303, A: Tol317, A: Hoh618, A: Hoh635,

conact list:


AtomAtomDistance (A)
FCE2 A:Phe1154.36
FCZ A:Phe1153.75
FCE1 A:Phe1154.72
FCB A:Val1304.91
FCG1 A:Val1303.58
FCB A:Leu3004.64
FCD1 A:Leu3004.88
FOG A:Ser3023.59
FC A:Ser3024.78
FN A:Cys3034.46
FCB A:Cys3033.56
FSG A:Cys3033.91
FCA A:Cys3034.42
FC12 A:Tol3173.61
FC11 A:Tol3174.20
FC1 A:Tol3171.30
FO1 A:Tol3172.40
FF2 A:Tol3170.00
FC2 A:Tol3172.35
FC6 A:Tol3174.94
FC5 A:Tol3174.15
FC7 A:Tol3174.76
FC4 A:Tol3173.73
FC3 A:Tol3172.76
FF3 A:Tol3172.08
FF1 A:Tol3172.10
FO A:Hoh6184.53
FO A:Hoh6354.83

interactive model:


Fluorine binding site 3 out of 3 in 2fzd


Fluorine binding site 3 out of 3 in 2fzd
Click to enlarge
stereopicture of Fluorine binding site 3 out of 3 in 2fzd
Click to enlarge
Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 3 of Fluorine in the PDB 2fzd. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Fluorine atom, shown by VdW sphere
Residues shown as a stick model or VDW spheres: A: Phe115, A: Phe122, A: Val130, A: Ser302, A: Tol317, A: Hoh487, A: Hoh592, A: Hoh618, A: Hoh635, A: Hoh657,

conact list:


AtomAtomDistance (A)
FCE2 A:Phe1154.68
FCZ A:Phe1154.69
FCB A:Phe1224.65
FCD1 A:Phe1223.42
FCE1 A:Phe1223.97
FCG A:Phe1224.38
FCG1 A:Val1304.28
FOG A:Ser3023.73
FC12 A:Tol3172.91
FC11 A:Tol3172.92
FC1 A:Tol3171.35
FO1 A:Tol3173.82
FF2 A:Tol3172.08
FC2 A:Tol3172.37
FC6 A:Tol3174.92
FC5 A:Tol3174.64
FC7 A:Tol3174.23
FC10 A:Tol3174.18
FC3 A:Tol3173.48
FF3 A:Tol3170.00
FF1 A:Tol3172.11
FO A:Hoh4873.16
FO A:Hoh5924.55
FO A:Hoh6183.23
FO A:Hoh6354.78
FO A:Hoh6574.87

interactive model:




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