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Atomistry » Fluorine » PDB 2fq9-2gtm » 2giq | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 2fq9-2gtm » 2giq » |
Fluorine in PDB 2giq: Hepatitis C Virus Rna-Dependent Rna Polymerase NS5B with Nni-2 InhibitorEnzymatic activity of Hepatitis C Virus Rna-Dependent Rna Polymerase NS5B with Nni-2 Inhibitor
All present enzymatic activity of Hepatitis C Virus Rna-Dependent Rna Polymerase NS5B with Nni-2 Inhibitor:
2.7.7.48; Protein crystallography data
The structure of Hepatitis C Virus Rna-Dependent Rna Polymerase NS5B with Nni-2 Inhibitor, PDB code: 2giq
was solved by
S.F.Harris,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Hepatitis C Virus Rna-Dependent Rna Polymerase NS5B with Nni-2 Inhibitor
(pdb code 2giq). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the Hepatitis C Virus Rna-Dependent Rna Polymerase NS5B with Nni-2 Inhibitor, PDB code: 2giq: Jump to Fluorine binding site number: 1; 2; Fluorine binding site 1 out of 2 in 2giqGo back to Fluorine Binding Sites List in 2giq
Fluorine binding site 1 out
of 2 in the Hepatitis C Virus Rna-Dependent Rna Polymerase NS5B with Nni-2 Inhibitor
Mono view Stereo pair view
Fluorine binding site 2 out of 2 in 2giqGo back to Fluorine Binding Sites List in 2giq
Fluorine binding site 2 out
of 2 in the Hepatitis C Virus Rna-Dependent Rna Polymerase NS5B with Nni-2 Inhibitor
Mono view Stereo pair view
Reference:
S.Le Pogam,
H.Kang,
S.F.Harris,
V.Leveque,
A.M.Giannetti,
S.Ali,
W.R.Jiang,
S.Rajyaguru,
G.Tavares,
C.Oshiro,
T.Hendricks,
K.Klumpp,
J.Symons,
M.F.Browner,
N.Cammack,
I.Najera.
Selection and Characterization of Replicon Variants Dually Resistant to Thumb- and Palm-Binding Nonnucleoside Polymerase Inhibitors of the Hepatitis C Virus. J.Virol. V. 80 6146 2006.
Page generated: Wed Jul 31 14:35:39 2024
ISSN: ISSN 0022-538X PubMed: 16731953 DOI: 10.1128/JVI.02628-05 |
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