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Atomistry » Fluorine » PDB 2gtn-2ihj » 2hzi » |
Fluorine in PDB 2hzi: Abl Kinase Domain in Complex with PD180970Enzymatic activity of Abl Kinase Domain in Complex with PD180970
All present enzymatic activity of Abl Kinase Domain in Complex with PD180970:
2.7.10.2; Protein crystallography data
The structure of Abl Kinase Domain in Complex with PD180970, PDB code: 2hzi
was solved by
S.W.Cowan-Jacob,
G.Fendrich,
J.Liebetanz,
D.Fabbro,
P.Manley,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 2hzi:
The structure of Abl Kinase Domain in Complex with PD180970 also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Abl Kinase Domain in Complex with PD180970
(pdb code 2hzi). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the Abl Kinase Domain in Complex with PD180970, PDB code: 2hzi: Jump to Fluorine binding site number: 1; 2; Fluorine binding site 1 out of 2 in 2hziGo back to Fluorine Binding Sites List in 2hzi
Fluorine binding site 1 out
of 2 in the Abl Kinase Domain in Complex with PD180970
Mono view Stereo pair view
Fluorine binding site 2 out of 2 in 2hziGo back to Fluorine Binding Sites List in 2hzi
Fluorine binding site 2 out
of 2 in the Abl Kinase Domain in Complex with PD180970
Mono view Stereo pair view
Reference:
S.W.Cowan-Jacob,
G.Fendrich,
A.Floersheimer,
P.Furet,
J.Liebetanz,
G.Rummel,
P.Rheinberger,
M.Centeleghe,
D.Fabbro,
P.W.Manley.
Structural Biology Contributions to the Discovery of Drugs to Treat Chronic Myelogenous Leukaemia. Acta Crystallogr.,Sect.D V. 63 80 2007.
Page generated: Sun Dec 13 11:36:59 2020
ISSN: ISSN 0907-4449 PubMed: 17164530 DOI: 10.1107/S0907444906047287 |
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