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Atomistry » Fluorine » PDB 2ihk-2jxr » 2ilt » |
Fluorine in PDB 2ilt: Human 11-Beta-Hydroxysteroid Dehydrogenase (HSD1) with Nadp and Adamantane Sulfone InhibitorEnzymatic activity of Human 11-Beta-Hydroxysteroid Dehydrogenase (HSD1) with Nadp and Adamantane Sulfone Inhibitor
All present enzymatic activity of Human 11-Beta-Hydroxysteroid Dehydrogenase (HSD1) with Nadp and Adamantane Sulfone Inhibitor:
1.1.1.146; Protein crystallography data
The structure of Human 11-Beta-Hydroxysteroid Dehydrogenase (HSD1) with Nadp and Adamantane Sulfone Inhibitor, PDB code: 2ilt
was solved by
K.L.Longenecker,
B.Sorensen,
R.Judge,
W.Qin,
J.T.Link,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 2ilt:
The structure of Human 11-Beta-Hydroxysteroid Dehydrogenase (HSD1) with Nadp and Adamantane Sulfone Inhibitor also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Human 11-Beta-Hydroxysteroid Dehydrogenase (HSD1) with Nadp and Adamantane Sulfone Inhibitor
(pdb code 2ilt). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Human 11-Beta-Hydroxysteroid Dehydrogenase (HSD1) with Nadp and Adamantane Sulfone Inhibitor, PDB code: 2ilt: Fluorine binding site 1 out of 1 in 2iltGo back to Fluorine Binding Sites List in 2ilt
Fluorine binding site 1 out
of 1 in the Human 11-Beta-Hydroxysteroid Dehydrogenase (HSD1) with Nadp and Adamantane Sulfone Inhibitor
Mono view Stereo pair view
Reference:
B.Sorensen,
M.Winn,
J.Rohde,
Q.Shuai,
J.Wang,
S.Fung,
K.Monzon,
W.Chiou,
D.Stolarik,
H.Imade,
L.Pan,
X.Deng,
L.Chovan,
K.Longenecker,
R.Judge,
W.Qin,
M.Brune,
H.Camp,
E.U.Frevert,
P.Jacobson,
J.T.Link.
Adamantane Sulfone and Sulfonamide 11-Beta-HSD1 Inhibitors. Bioorg.Med.Chem.Lett. V. 17 527 2007.
Page generated: Sun Dec 13 11:37:22 2020
ISSN: ISSN 0960-894X PubMed: 17070044 DOI: 10.1016/J.BMCL.2006.10.008 |
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