Fluorine in PDB 2kaw: uc(Nmr) Structure of the MDVL1 Pdz Domain in Complex with Its Inhibitor

The binding sites of Fluorine atom in the uc(Nmr) Structure of the MDVL1 Pdz Domain in Complex with Its Inhibitor (pdb code 2kaw). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the uc(Nmr) Structure of the MDVL1 Pdz Domain in Complex with Its Inhibitor, PDB code: 2kaw:

Fluorine binding site 1 out of 1 in the uc(Nmr) Structure of the MDVL1 Pdz Domain in Complex with Its Inhibitor


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of uc(Nmr) Structure of the MDVL1 Pdz Domain in Complex with Its Inhibitor within 5.0Å range: probe atom residue distance (Å) B Occ A:F91 b:20.0 occ:1.00 F A:SUZ91 0.0 20.0 1.0 C15 A:SUZ91 1.3 20.0 1.0 C14 A:SUZ91 2.4 20.0 1.0 C16 A:SUZ91 2.4 20.0 1.0 HA A:ARG75 2.5 0.0 1.0 HG3 A:ARG75 2.5 0.0 1.0 H16 A:SUZ91 2.6 20.0 1.0 H14 A:SUZ91 2.6 20.0 1.0 HG A:LEU74 2.7 0.0 1.0 HG22 A:VAL78 2.7 0.0 1.0 HG2 A:ARG75 2.8 0.0 1.0 HD21 A:LEU74 3.0 0.0 1.0 CG A:ARG75 3.1 0.0 1.0 CA A:ARG75 3.3 0.0 1.0 N A:ARG75 3.3 0.0 1.0 HB A:VAL78 3.3 0.0 1.0 CG A:LEU74 3.5 0.0 1.0 HB3 A:LEU74 3.5 0.0 1.0 CD2 A:LEU74 3.5 0.0 1.0 H A:ARG75 3.6 0.0 1.0 C13 A:SUZ91 3.6 20.0 1.0 C A:LEU74 3.6 0.0 1.0 C17 A:SUZ91 3.6 20.0 1.0 CG2 A:VAL78 3.6 0.0 1.0 HD23 A:LEU74 3.6 0.0 1.0 CB A:ARG75 3.7 0.0 1.0 HG12 A:VAL78 3.7 0.0 1.0 O A:LEU74 3.9 0.0 1.0 HG12 A:VAL71 3.9 0.0 1.0 CB A:LEU74 3.9 0.0 1.0 CB A:VAL78 3.9 0.0 1.0 HG23 A:VAL78 4.0 0.0 1.0 O A:VAL71 4.0 0.0 1.0 C18 A:SUZ91 4.1 20.0 1.0 HG13 A:VAL71 4.2 0.0 1.0 HB2 A:ARG75 4.2 0.0 1.0 CG1 A:VAL78 4.4 0.0 1.0 CD A:ARG75 4.4 0.0 1.0 CA A:LEU74 4.4 0.0 1.0 HG21 A:VAL78 4.4 0.0 1.0 HG13 A:ILE19 4.5 0.0 1.0 H17 A:SUZ91 4.5 20.0 1.0 HE A:ARG75 4.5 0.0 1.0 CG1 A:VAL71 4.6 0.0 1.0 HD22 A:LEU74 4.6 0.0 1.0 HA A:VAL71 4.6 0.0 1.0 HB3 A:ARG75 4.6 0.0 1.0 C A:ARG75 4.6 0.0 1.0 NE A:ARG75 4.6 0.0 1.0 H11A A:SUZ91 4.7 20.0 1.0 CD1 A:LEU74 4.8 0.0 1.0 H A:VAL78 4.8 0.0 1.0 HD2 A:ARG75 4.9 0.0 1.0 HD12 A:LEU74 4.9 0.0 1.0 HB2 A:LEU74 4.9 0.0 1.0 C10 A:SUZ91 5.0 20.0 1.0

H.J.Lee, N.X.Wang, D.L.Shi, J.J.Zheng. Sulindac Inhibits Canonical Wnt Signaling By Blocking the Pdz Domain of the Protein Dishevelled. Angew.Chem.Int.Ed.Engl. V. 48 6448 2009.
ISSN: ISSN 1433-7851
PubMed: 19637179
DOI: 10.1002/ANIE.200902981