Fluorine in PDB 2l1r: The Structure of the Calcium-Sensitizer, Dfbp-O, in Complex with the N-Domain of Troponin C and the Switch Region of Troponin I

The structure of The Structure of the Calcium-Sensitizer, Dfbp-O, in Complex with the N-Domain of Troponin C and the Switch Region of Troponin I also contains other interesting chemical elements:

Calcium

(Ca)

20 atoms

The binding sites of Fluorine atom in the The Structure of the Calcium-Sensitizer, Dfbp-O, in Complex with the N-Domain of Troponin C and the Switch Region of Troponin I (pdb code 2l1r). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the The Structure of the Calcium-Sensitizer, Dfbp-O, in Complex with the N-Domain of Troponin C and the Switch Region of Troponin I, PDB code: 2l1r:
Jump to Fluorine binding site number: 1; 2;

Fluorine binding site 1 out of 2 in the The Structure of the Calcium-Sensitizer, Dfbp-O, in Complex with the N-Domain of Troponin C and the Switch Region of Troponin I


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of The Structure of the Calcium-Sensitizer, Dfbp-O, in Complex with the N-Domain of Troponin C and the Switch Region of Troponin I within 5.0Å range: probe atom residue distance (Å) B Occ A:F91 b:20.0 occ:1.00 FCC A:SXK91 0.0 20.0 1.0 CAO A:SXK91 1.4 20.0 1.0 CAK A:SXK91 2.4 20.0 1.0 CAE A:SXK91 2.4 20.0 1.0 HAE A:SXK91 2.6 20.0 1.0 HAK A:SXK91 2.6 20.0 1.0 HE1 A:PHE77 2.8 0.0 1.0 CE1 A:PHE27 3.0 0.0 1.0 CZ A:PHE27 3.2 0.0 1.0 HE1 A:PHE27 3.2 0.0 1.0 HD12 A:ILE36 3.3 0.0 1.0 HD11 A:LEU41 3.3 0.0 1.0 HG21 A:ILE36 3.4 0.0 1.0 CD1 A:PHE27 3.4 0.0 1.0 HE2 B:MET153 3.5 0.0 1.0 HZ A:PHE27 3.5 0.0 1.0 HG22 A:ILE36 3.6 0.0 1.0 CAQ A:SXK91 3.7 20.0 1.0 CAJ A:SXK91 3.7 20.0 1.0 CE1 A:PHE77 3.7 0.0 1.0 HD1 A:PHE77 3.7 0.0 1.0 CE2 A:PHE27 3.8 0.0 1.0 HD1 A:PHE27 3.9 0.0 1.0 HE1 A:MET80 3.9 0.0 1.0 CG A:PHE27 3.9 0.0 1.0 HB2 A:LEU41 3.9 0.0 1.0 CG2 A:ILE36 4.0 0.0 1.0 CD2 A:PHE27 4.1 0.0 1.0 HA A:LEU41 4.1 0.0 1.0 HE1 B:MET153 4.1 0.0 1.0 CD1 A:PHE77 4.2 0.0 1.0 CAS A:SXK91 4.2 20.0 1.0 HG2 B:MET153 4.2 0.0 1.0 HE2 A:MET80 4.2 0.0 1.0 CD1 A:LEU41 4.3 0.0 1.0 CE B:MET153 4.3 0.0 1.0 CD1 A:ILE36 4.3 0.0 1.0 HD13 A:LEU41 4.4 0.0 1.0 HE2 A:PHE27 4.4 0.0 1.0 CE A:MET80 4.6 0.0 1.0 HAJ A:SXK91 4.6 20.0 1.0 HG23 A:ILE36 4.7 0.0 1.0 HB3 A:PHE27 4.7 0.0 1.0 CB A:LEU41 4.8 0.0 1.0 FDD A:SXK91 4.8 20.0 1.0 HD13 A:ILE36 4.8 0.0 1.0 HD22 A:LEU41 4.8 0.0 1.0 HD11 A:ILE36 4.8 0.0 1.0 HD2 A:PHE27 4.9 0.0 1.0 CZ A:PHE77 4.9 0.0 1.0 HG13 A:VAL72 4.9 0.0 1.0 HE3 B:MET153 4.9 0.0 1.0 CA A:LEU41 4.9 0.0 1.0 CB A:PHE27 5.0 0.0 1.0

Fluorine binding site 2 out of 2 in the The Structure of the Calcium-Sensitizer, Dfbp-O, in Complex with the N-Domain of Troponin C and the Switch Region of Troponin I


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of The Structure of the Calcium-Sensitizer, Dfbp-O, in Complex with the N-Domain of Troponin C and the Switch Region of Troponin I within 5.0Å range: probe atom residue distance (Å) B Occ A:F91 b:20.0 occ:1.00 FDD A:SXK91 0.0 20.0 1.0 CAQ A:SXK91 1.4 20.0 1.0 HD23 A:LEU41 2.3 0.0 1.0 CAK A:SXK91 2.4 20.0 1.0 CAS A:SXK91 2.4 20.0 1.0 HAK A:SXK91 2.6 20.0 1.0 HAH A:SXK91 2.7 20.0 1.0 CAR A:SXK91 2.9 20.0 1.0 HD22 A:LEU41 2.9 0.0 1.0 HB3 A:MET60 2.9 0.0 1.0 CAH A:SXK91 3.0 20.0 1.0 CD2 A:LEU41 3.0 0.0 1.0 SD A:MET60 3.1 0.0 1.0 HD13 A:LEU41 3.2 0.0 1.0 HG2 A:MET60 3.3 0.0 1.0 HE1 A:MET80 3.4 0.0 1.0 CG A:MET60 3.5 0.0 1.0 CB A:MET60 3.7 0.0 1.0 CAO A:SXK91 3.7 20.0 1.0 HD21 A:LEU41 3.7 0.0 1.0 CAJ A:SXK91 3.7 20.0 1.0 CAI A:SXK91 4.0 20.0 1.0 CD1 A:LEU41 4.0 0.0 1.0 HB2 A:MET60 4.1 0.0 1.0 SD A:MET80 4.1 0.0 1.0 CE A:MET80 4.1 0.0 1.0 CAF A:SXK91 4.1 20.0 1.0 CG A:LEU41 4.1 0.0 1.0 CAE A:SXK91 4.2 20.0 1.0 HD11 A:LEU41 4.2 0.0 1.0 HAI A:SXK91 4.4 20.0 1.0 HD11 A:LEU57 4.4 0.0 1.0 HE2 A:MET80 4.4 0.0 1.0 HE3 A:MET45 4.5 0.0 1.0 HB2 A:LEU41 4.5 0.0 1.0 HD12 B:ILE148 4.6 0.0 1.0 HG3 A:MET60 4.6 0.0 1.0 HAJ A:SXK91 4.6 20.0 1.0 HAF A:SXK91 4.7 20.0 1.0 FCC A:SXK91 4.8 20.0 1.0 CAG A:SXK91 4.9 20.0 1.0 HE1 A:MET45 4.9 0.0 1.0 HG A:LEU41 4.9 0.0 1.0 CA A:MET60 4.9 0.0 1.0 HE2 B:MET153 4.9 0.0 1.0 CE A:MET60 4.9 0.0 1.0 CAP A:SXK91 5.0 20.0 1.0 HD12 A:LEU41 5.0 0.0 1.0 HE2 A:MET45 5.0 0.0 1.0 CB A:LEU41 5.0 0.0 1.0

I.M.Robertson, Y.B.Sun, M.X.Li, B.D.Sykes. A Structural and Functional Perspective Into the Mechanism of Ca(2+)-Sensitizers That Target the Cardiac Troponin Complex. J.Mol.Cell.Cardiol. V. 49 1031 2010.
ISSN: ISSN 0022-2828
PubMed: 20801130
DOI: 10.1016/J.YJMCC.2010.08.019