Fluorine in PDB 2m1g: Parallel Human Telomeric Quadruplex Containing 2'F-Ana Substitutions

The binding sites of Fluorine atom in the Parallel Human Telomeric Quadruplex Containing 2'F-Ana Substitutions (pdb code 2m1g). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the Parallel Human Telomeric Quadruplex Containing 2'F-Ana Substitutions, PDB code: 2m1g:
Jump to Fluorine binding site number: 1; 2;

Fluorine binding site 1 out of 2 in the Parallel Human Telomeric Quadruplex Containing 2'F-Ana Substitutions


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Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Parallel Human Telomeric Quadruplex Containing 2'F-Ana Substitutions within 5.0Å range: probe atom residue distance (Å) B Occ A:F9 b:0.0 occ:1.00 F A:GFL9 0.0 0.0 1.0 C2' A:GFL9 1.4 0.0 1.0 H2' A:GFL9 2.0 0.0 1.0 H3' A:GFL9 2.4 0.0 1.0 C3' A:GFL9 2.4 0.0 1.0 C1' A:GFL9 2.4 0.0 1.0 H5'1 A:GFL9 2.7 0.0 1.0 H8 A:GFL9 2.7 0.0 1.0 N9 A:GFL9 2.7 0.0 1.0 C8 A:GFL9 2.8 0.0 1.0 H8 A:DG10 2.9 0.0 1.0 C4' A:GFL9 3.0 0.0 1.0 H2 A:DA8 3.1 0.0 1.0 O4' A:GFL9 3.2 0.0 1.0 C5' A:GFL9 3.2 0.0 1.0 H1' A:GFL9 3.3 0.0 1.0 N3 A:DA8 3.4 0.0 1.0 O3' A:GFL9 3.6 0.0 1.0 C2 A:DA8 3.7 0.0 1.0 O5' A:GFL9 3.7 0.0 1.0 C8 A:DG10 3.7 0.0 1.0 C4 A:GFL9 3.8 0.0 1.0 H2'' A:DA8 3.9 0.0 1.0 N7 A:GFL9 3.9 0.0 1.0 H4' A:GFL9 4.1 0.0 1.0 N7 A:DG10 4.1 0.0 1.0 OP2 A:DG10 4.2 0.0 1.0 H5'2 A:GFL9 4.2 0.0 1.0 O5' A:DG10 4.2 0.0 1.0 C5 A:GFL9 4.3 0.0 1.0 P A:DG10 4.3 0.0 1.0 H22 A:DG4 4.5 0.0 1.0 H1' A:DA8 4.6 0.0 1.0 N3 A:GFL9 4.7 0.0 1.0 C4 A:DA8 4.7 0.0 1.0 O4' A:DG10 4.7 0.0 1.0 N9 A:DG10 4.7 0.0 1.0 H21 A:DG4 4.8 0.0 1.0 C2' A:DA8 4.9 0.0 1.0 H5' A:DG10 4.9 0.0 1.0 N1 A:DA8 5.0 0.0 1.0 N2 A:DG4 5.0 0.0 1.0 H2' A:DG10 5.0 0.0 1.0

Fluorine binding site 2 out of 2 in the Parallel Human Telomeric Quadruplex Containing 2'F-Ana Substitutions


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Parallel Human Telomeric Quadruplex Containing 2'F-Ana Substitutions within 5.0Å range: probe atom residue distance (Å) B Occ B:F21 b:0.0 occ:1.00 F B:GFL21 0.0 0.0 1.0 C2' B:GFL21 1.4 0.0 1.0 H2' B:GFL21 2.0 0.0 1.0 C3' B:GFL21 2.4 0.0 1.0 C1' B:GFL21 2.4 0.0 1.0 H3' B:GFL21 2.4 0.0 1.0 H5'1 B:GFL21 2.6 0.0 1.0 H2'' B:DA20 2.6 0.0 1.0 N9 B:GFL21 2.7 0.0 1.0 H8 B:DG22 2.7 0.0 1.0 H8 B:GFL21 2.8 0.0 1.0 C8 B:GFL21 2.9 0.0 1.0 C4' B:GFL21 3.0 0.0 1.0 O4' B:GFL21 3.1 0.0 1.0 C5' B:GFL21 3.2 0.0 1.0 H1' B:GFL21 3.3 0.0 1.0 C2' B:DA20 3.5 0.0 1.0 O3' B:GFL21 3.6 0.0 1.0 C8 B:DG22 3.6 0.0 1.0 H1' B:DA20 3.7 0.0 1.0 C4 B:GFL21 3.7 0.0 1.0 H2' B:DA20 3.8 0.0 1.0 O5' B:GFL21 3.9 0.0 1.0 N7 B:GFL21 4.0 0.0 1.0 H4' B:GFL21 4.0 0.0 1.0 C1' B:DA20 4.1 0.0 1.0 H5'2 B:GFL21 4.1 0.0 1.0 N7 B:DG22 4.2 0.0 1.0 O5' B:DG22 4.2 0.0 1.0 C5 B:GFL21 4.3 0.0 1.0 N3 B:DA20 4.4 0.0 1.0 P B:DG22 4.4 0.0 1.0 N9 B:DA20 4.4 0.0 1.0 C4 B:DA20 4.5 0.0 1.0 OP2 B:DG22 4.5 0.0 1.0 N3 B:GFL21 4.6 0.0 1.0 H22 B:DG16 4.6 0.0 1.0 H2' B:DG22 4.7 0.0 1.0 N9 B:DG22 4.7 0.0 1.0 O3' B:DA20 4.7 0.0 1.0 C3' B:DA20 4.8 0.0 1.0 O4' B:DG22 4.8 0.0 1.0 H21 B:DG16 4.9 0.0 1.0 O4 B:DT13 4.9 0.0 1.0

N.Martin-Pintado, M.Yahyaee-Anzahaee, G.F.Deleavey, G.Portella, M.Orozco, M.J.Damha, C.Gonzalez. Dramatic Effect of Furanose C2' Substitution on Structure and Stability: Directing the Folding of the Human Telomeric Quadruplex with A Single Fluorine Atom. J.Am.Chem.Soc. V. 135 5344 2013.
ISSN: ISSN 0002-7863
PubMed: 23521511
DOI: 10.1021/JA401954T