Atomistry » Fluorine » PDB 2k1q-2ogz » 2ode
Atomistry »
  Fluorine »
    PDB 2k1q-2ogz »
      2ode »

Fluorine in PDB 2ode: Crystal Structure of the Heterodimeric Complex of Human RGS8 and Activated Gi Alpha 3

Protein crystallography data

The structure of Crystal Structure of the Heterodimeric Complex of Human RGS8 and Activated Gi Alpha 3, PDB code: 2ode was solved by C.Gileadi, M.Soundararajan, A.P.Turnbull, J.M.Elkins, E.Papagrigoriou, A.C.W.Pike, G.Bunkoczi, F.Gorrec, C.Umeano, F.Von Delft, J.Weigelt, A.Edwards, C.H.Arrowsmith, M.Sundstrom, D.A.Doyle, Structural Genomicsconsortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 29.40 / 1.90
Space group P 21 21 2
Cell size a, b, c (Å), α, β, γ (°) 112.837, 130.216, 68.519, 90.00, 90.00, 90.00
R / Rfree (%) 18 / 21.1

Other elements in 2ode:

The structure of Crystal Structure of the Heterodimeric Complex of Human RGS8 and Activated Gi Alpha 3 also contains other interesting chemical elements:

Magnesium (Mg) 2 atoms
Aluminium (Al) 2 atoms

Fluorine Binding Sites:

The binding sites of Fluorine atom in the Crystal Structure of the Heterodimeric Complex of Human RGS8 and Activated Gi Alpha 3 (pdb code 2ode). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total 8 binding sites of Fluorine where determined in the Crystal Structure of the Heterodimeric Complex of Human RGS8 and Activated Gi Alpha 3, PDB code: 2ode:
Jump to Fluorine binding site number: 1; 2; 3; 4; 5; 6; 7; 8;

Fluorine binding site 1 out of 8 in 2ode

Go back to Fluorine Binding Sites List in 2ode
Fluorine binding site 1 out of 8 in the Crystal Structure of the Heterodimeric Complex of Human RGS8 and Activated Gi Alpha 3


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Crystal Structure of the Heterodimeric Complex of Human RGS8 and Activated Gi Alpha 3 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F2001

b:22.5
occ:1.00
 F1 A:ALF2001 0.0 22.5 1.0
AL A:ALF2001 1.8 20.4 1.0
F4 A:ALF2001 2.5 21.4 1.0
O A:HOH3236 2.6 18.5 1.0
F3 A:ALF2001 2.6 22.2 1.0
O2B A:GDP1001 2.6 18.8 1.0
N A:GLY203 2.7 32.1 1.0
NZ A:LYS46 2.8 32.2 1.0
CA A:GLY203 3.2 32.1 1.0
CA A:GLY42 3.3 33.8 1.0
CE A:LYS46 3.4 31.7 1.0
F2 A:ALF2001 3.6 23.9 1.0
PB A:GDP1001 3.7 19.4 1.0
O3B A:GDP1001 3.7 21.2 1.0
N A:GLU43 3.7 34.3 1.0
C A:GLY202 3.8 32.5 1.0
O A:ALA41 4.0 33.4 1.0
N A:GLY42 4.0 33.3 1.0
C A:GLY42 4.0 33.9 1.0
OE1 A:GLN204 4.1 32.5 1.0
CA A:GLY202 4.1 32.7 1.0
C A:GLY203 4.1 32.6 1.0
NE2 A:GLN204 4.2 30.5 1.0
C A:ALA41 4.3 32.5 1.0
O1B A:GDP1001 4.3 22.3 1.0
O A:VAL201 4.3 32.8 1.0
N A:GLN204 4.3 32.4 1.0
MG A:MG3001 4.4 20.2 1.0
CD A:GLN204 4.5 29.9 1.0
O A:HOH3229 4.5 23.1 1.0
O A:GLY40 4.8 33.2 1.0
O A:GLY202 4.8 32.3 1.0
CD A:LYS46 4.9 31.8 1.0
CA A:GLU43 4.9 35.3 1.0

Fluorine binding site 2 out of 8 in 2ode

Go back to Fluorine Binding Sites List in 2ode
Fluorine binding site 2 out of 8 in the Crystal Structure of the Heterodimeric Complex of Human RGS8 and Activated Gi Alpha 3


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 2 of Crystal Structure of the Heterodimeric Complex of Human RGS8 and Activated Gi Alpha 3 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F2001

b:23.9
occ:1.00
 F2 A:ALF2001 0.0 23.9 1.0
AL A:ALF2001 1.8 20.4 1.0
F3 A:ALF2001 2.3 22.2 1.0
F4 A:ALF2001 2.5 21.4 1.0
N A:THR181 2.7 32.4 1.0
NH1 A:ARG178 2.7 34.5 1.0
O A:HOH3236 2.8 18.5 1.0
O2B A:GDP1001 2.8 18.8 1.0
O A:HOH3231 2.9 19.9 1.0
CA A:LYS180 3.1 33.0 1.0
NH2 A:ARG178 3.1 36.0 1.0
CZ A:ARG178 3.3 36.6 1.0
MG A:MG3001 3.4 20.2 1.0
C A:LYS180 3.4 32.7 1.0
F1 A:ALF2001 3.6 22.5 1.0
CG A:LYS180 3.7 34.2 1.0
O A:VAL179 3.8 32.6 1.0
OG1 A:THR181 3.8 31.0 1.0
CB A:LYS180 3.8 32.8 1.0
CA A:THR181 3.9 33.0 1.0
PB A:GDP1001 3.9 19.4 1.0
O1B A:GDP1001 4.0 22.3 1.0
CB A:THR181 4.0 33.6 1.0
N A:LYS180 4.1 33.2 1.0
O A:THR181 4.3 32.6 1.0
C A:VAL179 4.3 32.8 1.0
O1A A:GDP1001 4.4 19.4 1.0
NE A:ARG178 4.5 35.1 1.0
C A:THR181 4.6 32.1 1.0
O A:LYS180 4.6 31.6 1.0
O3A A:GDP1001 4.7 20.1 1.0
CD A:LYS180 4.7 35.6 1.0
NE2 A:GLN204 4.7 30.5 1.0
OE1 A:GLN204 4.8 32.5 1.0
N A:GLU43 4.9 34.3 1.0
O A:HOH3229 4.9 23.1 1.0

Fluorine binding site 3 out of 8 in 2ode

Go back to Fluorine Binding Sites List in 2ode
Fluorine binding site 3 out of 8 in the Crystal Structure of the Heterodimeric Complex of Human RGS8 and Activated Gi Alpha 3


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 3 of Crystal Structure of the Heterodimeric Complex of Human RGS8 and Activated Gi Alpha 3 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F2001

b:22.2
occ:1.00
 F3 A:ALF2001 0.0 22.2 1.0
AL A:ALF2001 1.8 20.4 1.0
MG A:MG3001 2.0 20.2 1.0
F2 A:ALF2001 2.3 23.9 1.0
O2B A:GDP1001 2.6 18.8 1.0
F1 A:ALF2001 2.6 22.5 1.0
O A:HOH3236 2.7 18.5 1.0
O A:HOH3229 2.7 23.1 1.0
O1B A:GDP1001 2.9 22.3 1.0
OG1 A:THR181 2.9 31.0 1.0
CB A:THR181 3.1 33.6 1.0
O A:HOH3231 3.2 19.9 1.0
PB A:GDP1001 3.2 19.4 1.0
N A:THR181 3.5 32.4 1.0
F4 A:ALF2001 3.5 21.4 1.0
O A:VAL201 3.8 32.8 1.0
CA A:THR181 3.8 33.0 1.0
OG A:SER47 4.0 31.8 1.0
O3B A:GDP1001 4.1 21.2 1.0
O A:THR181 4.1 32.6 1.0
CE A:LYS46 4.1 31.7 1.0
NZ A:LYS46 4.2 32.2 1.0
CA A:GLY202 4.2 32.7 1.0
CG2 A:THR181 4.3 34.3 1.0
N A:GLY203 4.4 32.1 1.0
C A:THR181 4.4 32.1 1.0
NH1 A:ARG178 4.6 34.5 1.0
O3A A:GDP1001 4.6 20.1 1.0
C A:VAL201 4.7 32.1 1.0
C A:LYS180 4.7 32.7 1.0
C A:GLY202 4.8 32.5 1.0
N A:GLY202 4.9 32.3 1.0
CA A:LYS180 5.0 33.0 1.0

Fluorine binding site 4 out of 8 in 2ode

Go back to Fluorine Binding Sites List in 2ode
Fluorine binding site 4 out of 8 in the Crystal Structure of the Heterodimeric Complex of Human RGS8 and Activated Gi Alpha 3


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 4 of Crystal Structure of the Heterodimeric Complex of Human RGS8 and Activated Gi Alpha 3 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F2001

b:21.4
occ:1.00
 F4 A:ALF2001 0.0 21.4 1.0
AL A:ALF2001 1.8 20.4 1.0
F1 A:ALF2001 2.5 22.5 1.0
F2 A:ALF2001 2.5 23.9 1.0
O2B A:GDP1001 2.7 18.8 1.0
NE2 A:GLN204 2.7 30.5 1.0
O A:HOH3236 2.7 18.5 1.0
NH2 A:ARG178 2.9 36.0 1.0
N A:GLU43 3.0 34.3 1.0
CA A:GLY42 3.3 33.8 1.0
CD A:GLN204 3.5 29.9 1.0
F3 A:ALF2001 3.5 22.2 1.0
OE1 A:GLN204 3.5 32.5 1.0
C A:GLY42 3.6 33.9 1.0
NH1 A:ARG178 3.6 34.5 1.0
CZ A:ARG178 3.6 36.6 1.0
CA A:GLU43 4.0 35.3 1.0
CG A:GLU43 4.0 38.5 1.0
PB A:GDP1001 4.2 19.4 1.0
CG A:LYS180 4.3 34.2 1.0
O A:HOH3031 4.5 26.7 1.0
CD A:LYS180 4.6 35.6 1.0
N A:GLY42 4.6 33.3 1.0
N A:GLY203 4.6 32.1 1.0
CB A:GLU43 4.6 35.6 1.0
O3B A:GDP1001 4.8 21.2 1.0
O A:GLY42 4.8 33.6 1.0
O3A A:GDP1001 4.9 20.1 1.0
N A:THR181 4.9 32.4 1.0
NE A:ARG178 4.9 35.1 1.0
CG A:GLN204 4.9 29.6 1.0
CA A:LYS180 4.9 33.0 1.0
NZ A:LYS46 5.0 32.2 1.0
O1B A:GDP1001 5.0 22.3 1.0

Fluorine binding site 5 out of 8 in 2ode

Go back to Fluorine Binding Sites List in 2ode
Fluorine binding site 5 out of 8 in the Crystal Structure of the Heterodimeric Complex of Human RGS8 and Activated Gi Alpha 3


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 5 of Crystal Structure of the Heterodimeric Complex of Human RGS8 and Activated Gi Alpha 3 within 5.0Å range:
probe atom residue distance (Å) B Occ
C:F2002

b:24.6
occ:1.00
 F1 C:ALF2002 0.0 24.6 1.0
AL C:ALF2002 1.8 23.9 1.0
MG C:MG3002 2.0 24.7 1.0
F4 C:ALF2002 2.4 27.4 1.0
F3 C:ALF2002 2.6 22.0 1.0
O C:HOH3194 2.6 18.7 1.0
O2B C:GDP1002 2.7 22.0 1.0
O C:HOH3190 2.7 21.4 1.0
O1B C:GDP1002 2.9 19.8 1.0
OG1 C:THR181 3.0 32.1 1.0
CB C:THR181 3.1 31.3 1.0
PB C:GDP1002 3.3 21.2 1.0
O C:HOH3187 3.4 22.7 1.0
F2 C:ALF2002 3.5 22.9 1.0
N C:THR181 3.6 30.3 1.0
O C:VAL201 3.7 31.0 1.0
CA C:THR181 3.8 31.6 1.0
CA C:GLY202 4.0 32.2 1.0
O C:THR181 4.0 32.2 1.0
NZ C:LYS46 4.1 32.0 1.0
CE C:LYS46 4.1 32.5 1.0
O3B C:GDP1002 4.1 20.3 1.0
OG C:SER47 4.1 30.8 1.0
N C:GLY203 4.3 32.7 1.0
CG2 C:THR181 4.3 32.0 1.0
C C:THR181 4.4 31.1 1.0
C C:VAL201 4.5 31.1 1.0
NH1 C:ARG178 4.6 33.1 1.0
C C:GLY202 4.7 33.0 1.0
N C:GLY202 4.7 31.8 1.0
O3A C:GDP1002 4.7 18.9 1.0
C C:LYS180 4.8 29.6 1.0

Fluorine binding site 6 out of 8 in 2ode

Go back to Fluorine Binding Sites List in 2ode
Fluorine binding site 6 out of 8 in the Crystal Structure of the Heterodimeric Complex of Human RGS8 and Activated Gi Alpha 3


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 6 of Crystal Structure of the Heterodimeric Complex of Human RGS8 and Activated Gi Alpha 3 within 5.0Å range:
probe atom residue distance (Å) B Occ
C:F2002

b:22.9
occ:1.00
 F2 C:ALF2002 0.0 22.9 1.0
AL C:ALF2002 1.8 23.9 1.0
F4 C:ALF2002 2.5 27.4 1.0
F3 C:ALF2002 2.6 22.0 1.0
O2B C:GDP1002 2.6 22.0 1.0
NE2 C:GLN204 2.7 31.5 1.0
O C:HOH3194 2.8 18.7 1.0
NH2 C:ARG178 2.9 32.0 1.0
N C:GLU43 3.0 33.7 1.0
CA C:GLY42 3.3 34.0 1.0
NH1 C:ARG178 3.5 33.1 1.0
CD C:GLN204 3.5 30.6 1.0
F1 C:ALF2002 3.5 24.6 1.0
OE1 C:GLN204 3.5 33.0 1.0
C C:GLY42 3.6 34.5 1.0
CZ C:ARG178 3.6 35.5 1.0
CA C:GLU43 3.9 34.4 0.5
CA C:GLU43 3.9 34.4 0.5
CG C:GLU43 4.0 35.0 0.5
CG C:GLU43 4.1 34.2 0.5
PB C:GDP1002 4.1 21.2 1.0
CG C:LYS180 4.3 34.6 1.0
CB C:GLU43 4.5 34.1 0.5
CB C:GLU43 4.6 34.2 0.5
N C:GLY42 4.6 33.3 1.0
O C:HOH3076 4.6 31.1 1.0
O C:HOH3200 4.6 39.4 1.0
CD C:LYS180 4.7 35.8 1.0
N C:GLY203 4.7 32.7 1.0
O C:GLY42 4.8 33.7 1.0
O3B C:GDP1002 4.8 20.3 1.0
O3A C:GDP1002 4.9 18.9 1.0
NE C:ARG178 4.9 35.2 1.0
O1B C:GDP1002 4.9 19.8 1.0
CG C:GLN204 4.9 33.1 1.0
CB C:LYS180 4.9 31.4 1.0
CA C:LYS180 4.9 30.8 1.0
N C:THR181 5.0 30.3 1.0
NZ C:LYS46 5.0 32.0 1.0

Fluorine binding site 7 out of 8 in 2ode

Go back to Fluorine Binding Sites List in 2ode
Fluorine binding site 7 out of 8 in the Crystal Structure of the Heterodimeric Complex of Human RGS8 and Activated Gi Alpha 3


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 7 of Crystal Structure of the Heterodimeric Complex of Human RGS8 and Activated Gi Alpha 3 within 5.0Å range:
probe atom residue distance (Å) B Occ
C:F2002

b:22.0
occ:1.00
 F3 C:ALF2002 0.0 22.0 1.0
AL C:ALF2002 1.8 23.9 1.0
F1 C:ALF2002 2.6 24.6 1.0
O C:HOH3194 2.6 18.7 1.0
F2 C:ALF2002 2.6 22.9 1.0
O2B C:GDP1002 2.7 22.0 1.0
NZ C:LYS46 2.7 32.0 1.0
N C:GLY203 2.8 32.7 1.0
CA C:GLY203 3.3 32.2 1.0
CA C:GLY42 3.3 34.0 1.0
CE C:LYS46 3.5 32.5 1.0
F4 C:ALF2002 3.6 27.4 1.0
PB C:GDP1002 3.6 21.2 1.0
N C:GLU43 3.7 33.7 1.0
O3B C:GDP1002 3.8 20.3 1.0
C C:GLY202 3.8 33.0 1.0
O C:ALA41 3.9 32.7 1.0
N C:GLY42 3.9 33.3 1.0
CA C:GLY202 4.0 32.2 1.0
C C:GLY42 4.0 34.5 1.0
OE1 C:GLN204 4.1 33.0 1.0
C C:ALA41 4.2 33.3 1.0
C C:GLY203 4.2 32.4 1.0
O1B C:GDP1002 4.2 19.8 1.0
O C:VAL201 4.2 31.0 1.0
MG C:MG3002 4.3 24.7 1.0
NE2 C:GLN204 4.3 31.5 1.0
N C:GLN204 4.3 32.9 1.0
O C:HOH3190 4.5 21.4 1.0
CD C:GLN204 4.5 30.6 1.0
O C:GLY40 4.7 34.8 1.0
O C:GLY202 4.9 32.0 1.0
CA C:GLU43 4.9 34.4 0.5
CA C:GLU43 4.9 34.4 0.5
CD C:LYS46 4.9 32.6 1.0

Fluorine binding site 8 out of 8 in 2ode

Go back to Fluorine Binding Sites List in 2ode
Fluorine binding site 8 out of 8 in the Crystal Structure of the Heterodimeric Complex of Human RGS8 and Activated Gi Alpha 3


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 8 of Crystal Structure of the Heterodimeric Complex of Human RGS8 and Activated Gi Alpha 3 within 5.0Å range:
probe atom residue distance (Å) B Occ
C:F2002

b:27.4
occ:1.00
 F4 C:ALF2002 0.0 27.4 1.0
AL C:ALF2002 1.8 23.9 1.0
F1 C:ALF2002 2.4 24.6 1.0
F2 C:ALF2002 2.5 22.9 1.0
NH1 C:ARG178 2.6 33.1 1.0
O2B C:GDP1002 2.6 22.0 1.0
O C:HOH3194 2.8 18.7 1.0
N C:THR181 2.9 30.3 1.0
O C:HOH3187 3.0 22.7 1.0
NH2 C:ARG178 3.1 32.0 1.0
CA C:LYS180 3.2 30.8 1.0
CZ C:ARG178 3.3 35.5 1.0
MG C:MG3002 3.3 24.7 1.0
C C:LYS180 3.5 29.6 1.0
F3 C:ALF2002 3.6 22.0 1.0
CG C:LYS180 3.7 34.6 1.0
PB C:GDP1002 3.8 21.2 1.0
O C:VAL179 3.8 30.8 1.0
O1B C:GDP1002 3.8 19.8 1.0
CB C:LYS180 3.9 31.4 1.0
OG1 C:THR181 3.9 32.1 1.0
CA C:THR181 4.0 31.6 1.0
CB C:THR181 4.1 31.3 1.0
N C:LYS180 4.2 30.6 1.0
O C:THR181 4.3 32.2 1.0
O1A C:GDP1002 4.4 22.3 1.0
C C:VAL179 4.4 31.8 1.0
NE C:ARG178 4.5 35.2 1.0
O3A C:GDP1002 4.6 18.9 1.0
C C:THR181 4.7 31.1 1.0
NE2 C:GLN204 4.8 31.5 1.0
O C:LYS180 4.8 28.7 1.0
N C:GLU43 4.8 33.7 1.0
OE1 C:GLN204 4.8 33.0 1.0
CD C:LYS180 4.8 35.8 1.0
O C:HOH3190 4.9 21.4 1.0

Reference:

M.Soundararajan, F.S.Willard, A.J.Kimple, A.P.Turnbull, L.J.Ball, G.A.Schoch, C.Gileadi, O.Y.Fedorov, E.F.Dowler, V.A.Higman, S.Q.Hutsell, M.Sundstrom, D.A.Doyle, D.P.Siderovski. Structural Diversity in the Rgs Domain and Its Interaction with Heterotrimeric G Protein Alpha-Subunits. Proc.Natl.Acad.Sci.Usa V. 105 6457 2008.
ISSN: ISSN 0027-8424
PubMed: 18434541
DOI: 10.1073/PNAS.0801508105
Page generated: Wed Jul 31 15:17:46 2024

Last articles

Zn in 9JYW
Zn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy