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Atomistry » Fluorine » PDB 2oh4-2pdk » 2pdi | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 2oh4-2pdk » 2pdi » |
Fluorine in PDB 2pdi: Human Aldose Reductase Mutant L300A Complexed with Zopolrestat at 1.55 A.Enzymatic activity of Human Aldose Reductase Mutant L300A Complexed with Zopolrestat at 1.55 A.
All present enzymatic activity of Human Aldose Reductase Mutant L300A Complexed with Zopolrestat at 1.55 A.:
1.1.1.21; Protein crystallography data
The structure of Human Aldose Reductase Mutant L300A Complexed with Zopolrestat at 1.55 A., PDB code: 2pdi
was solved by
H.Steuber,
A.Heine,
G.Klebe,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Human Aldose Reductase Mutant L300A Complexed with Zopolrestat at 1.55 A.
(pdb code 2pdi). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 3 binding sites of Fluorine where determined in the Human Aldose Reductase Mutant L300A Complexed with Zopolrestat at 1.55 A., PDB code: 2pdi: Jump to Fluorine binding site number: 1; 2; 3; Fluorine binding site 1 out of 3 in 2pdiGo back to Fluorine Binding Sites List in 2pdi
Fluorine binding site 1 out
of 3 in the Human Aldose Reductase Mutant L300A Complexed with Zopolrestat at 1.55 A.
Mono view Stereo pair view
Fluorine binding site 2 out of 3 in 2pdiGo back to Fluorine Binding Sites List in 2pdi
Fluorine binding site 2 out
of 3 in the Human Aldose Reductase Mutant L300A Complexed with Zopolrestat at 1.55 A.
Mono view Stereo pair view
Fluorine binding site 3 out of 3 in 2pdiGo back to Fluorine Binding Sites List in 2pdi
Fluorine binding site 3 out
of 3 in the Human Aldose Reductase Mutant L300A Complexed with Zopolrestat at 1.55 A.
Mono view Stereo pair view
Reference:
H.Steuber,
A.Heine,
A.Podjarny,
G.Klebe.
Merging the Binding Sites of Aldose and Aldehyde Reductase For Detection of Inhibitor Selectivity-Determining Features. J.Mol.Biol. V. 379 991 2008.
Page generated: Wed Jul 31 15:31:08 2024
ISSN: ISSN 0022-2836 PubMed: 18495158 DOI: 10.1016/J.JMB.2008.03.063 |
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