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Atomistry » Fluorine » PDB 2pdl-2q94 » 2phb » |
Fluorine in PDB 2phb: An Orally Efficacious Factor Xa InhibitorEnzymatic activity of An Orally Efficacious Factor Xa Inhibitor
All present enzymatic activity of An Orally Efficacious Factor Xa Inhibitor:
3.4.21.6; Protein crystallography data
The structure of An Orally Efficacious Factor Xa Inhibitor, PDB code: 2phb
was solved by
E.Zhang,
J.T.Kohrt,
C.F.Bigge,
B.C.Finzel,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 2phb:
The structure of An Orally Efficacious Factor Xa Inhibitor also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the An Orally Efficacious Factor Xa Inhibitor
(pdb code 2phb). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the An Orally Efficacious Factor Xa Inhibitor, PDB code: 2phb: Fluorine binding site 1 out of 1 in 2phbGo back to Fluorine Binding Sites List in 2phb
Fluorine binding site 1 out
of 1 in the An Orally Efficacious Factor Xa Inhibitor
Mono view Stereo pair view
Reference:
J.T.Kohrt,
C.F.Bigge,
J.W.Bryant,
A.Casimiro-Garcia,
L.Chi,
W.L.Cody,
T.Dahring,
D.A.Dudley,
K.J.Filipski,
S.Haarer,
R.Heemstra,
N.Janiczek,
L.Narasimhan,
T.Mcclanahan,
J.T.Peterson,
V.Sahasrabudhe,
R.Schaum,
C.A.Van Huis,
K.M.Welch,
E.Zhang,
R.J.Leadley,
J.J.Edmunds.
The Discovery of (2R,4R)-N-(4-Chlorophenyl)-N- (2-Fluoro-4-(2-Oxopyridin-1(2H)-Yl)Phenyl) -4-Methoxypyrrolidine-1,2-Dicarboxamide (Pd 0348292), An Orally Efficacious Factor Xa Inhibitor Chem.Biol.Drug Des. V. 70 100 2007.
Page generated: Sun Dec 13 11:39:04 2020
ISSN: ISSN 1747-0277 PubMed: 17683371 DOI: 10.1111/J.1747-0285.2007.00539.X |
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