Fluorine »
PDB 2rfn-2vfz »
2v7w »
Fluorine in PDB 2v7w: X-Ray Crystal Structure of 5'-Fluorodeoxyadenosine Synthase S158G Mutant Complexed with 5'-Fluorodeoxyadenosin
Enzymatic activity of X-Ray Crystal Structure of 5'-Fluorodeoxyadenosine Synthase S158G Mutant Complexed with 5'-Fluorodeoxyadenosin
All present enzymatic activity of X-Ray Crystal Structure of 5'-Fluorodeoxyadenosine Synthase S158G Mutant Complexed with 5'-Fluorodeoxyadenosin:
2.5.1.63;
2.5.1.63;
Protein crystallography data
The structure of X-Ray Crystal Structure of 5'-Fluorodeoxyadenosine Synthase S158G Mutant Complexed with 5'-Fluorodeoxyadenosin, PDB code: 2v7w
was solved by
X.Zhu,
D.O'hagan,
J.H.Naismith,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 53.38 / 1.90 |
| Space group | C 2 2 21 |
| Cell size a, b, c (Å), α, β, γ (°) | 75.854, 129.256, 184.485, 90.00, 90.00, 90.00 |
| R / Rfree (%) | 18.7 / 22.1 |
Fluorine Binding Sites:
The binding sites of Fluorine atom in the X-Ray Crystal Structure of 5'-Fluorodeoxyadenosine Synthase S158G Mutant Complexed with 5'-Fluorodeoxyadenosin
(pdb code 2v7w). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 3 binding sites of Fluorine where determined in the X-Ray Crystal Structure of 5'-Fluorodeoxyadenosine Synthase S158G Mutant Complexed with 5'-Fluorodeoxyadenosin, PDB code: 2v7w:
Jump to Fluorine binding site number: 1; 2; 3;
In total 3 binding sites of Fluorine where determined in the X-Ray Crystal Structure of 5'-Fluorodeoxyadenosine Synthase S158G Mutant Complexed with 5'-Fluorodeoxyadenosin, PDB code: 2v7w:
Jump to Fluorine binding site number: 1; 2; 3;
Fluorine binding site 1 out of 3 in 2v7w
Go back to
Fluorine Binding Sites List in 2v7w
Fluorine binding site 1 out
of 3 in the X-Ray Crystal Structure of 5'-Fluorodeoxyadenosine Synthase S158G Mutant Complexed with 5'-Fluorodeoxyadenosin
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 1 of X-Ray Crystal Structure of 5'-Fluorodeoxyadenosine Synthase S158G Mutant Complexed with 5'-Fluorodeoxyadenosin within 5.0Å range:
|
Fluorine binding site 2 out of 3 in 2v7w
Go back to
Fluorine Binding Sites List in 2v7w
Fluorine binding site 2 out
of 3 in the X-Ray Crystal Structure of 5'-Fluorodeoxyadenosine Synthase S158G Mutant Complexed with 5'-Fluorodeoxyadenosin
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 2 of X-Ray Crystal Structure of 5'-Fluorodeoxyadenosine Synthase S158G Mutant Complexed with 5'-Fluorodeoxyadenosin within 5.0Å range:
|
Fluorine binding site 3 out of 3 in 2v7w
Go back to
Fluorine Binding Sites List in 2v7w
Fluorine binding site 3 out
of 3 in the X-Ray Crystal Structure of 5'-Fluorodeoxyadenosine Synthase S158G Mutant Complexed with 5'-Fluorodeoxyadenosin
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 3 of X-Ray Crystal Structure of 5'-Fluorodeoxyadenosine Synthase S158G Mutant Complexed with 5'-Fluorodeoxyadenosin within 5.0Å range:
|
Reference:
X.Zhu,
D.A.Robinson,
A.R.Mcewan,
D.O'hagan,
J.H.Naismith.
Mechanism of Enzymatic Fluorination in Streptomyces Cattleya. J. Am. Chem. Soc. V. 129 14597 2007.
ISSN: ESSN 1520-5126
PubMed: 17985882
DOI: 10.1021/JA0731569
Page generated: Sun Dec 13 11:40:11 2020
ISSN: ESSN 1520-5126
PubMed: 17985882
DOI: 10.1021/JA0731569
Last articles
Zn in 8WB0Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
