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Atomistry » Fluorine » PDB 2vh0-2wbk » 2vh6 » |
Fluorine in PDB 2vh6: Structure and Property Based Design of Factor Xa Inhibitors: Pyrrolidin-2-Ones with Biaryl P4 MotifsEnzymatic activity of Structure and Property Based Design of Factor Xa Inhibitors: Pyrrolidin-2-Ones with Biaryl P4 Motifs
All present enzymatic activity of Structure and Property Based Design of Factor Xa Inhibitors: Pyrrolidin-2-Ones with Biaryl P4 Motifs:
3.4.21.6; Protein crystallography data
The structure of Structure and Property Based Design of Factor Xa Inhibitors: Pyrrolidin-2-Ones with Biaryl P4 Motifs, PDB code: 2vh6
was solved by
R.J.Young,
A.D.Borthwick,
D.Brown,
C.L.Burns-Kurtis,
M.Campbell,
C.Chan,
M.Charbaut,
C.W.Chung,
M.A.Convery,
H.A.Kelly,
N.P.King,
S.Kleanthous,
A.M.Mason,
A.J.Pateman,
A.N.Patikis,
I.L.Pinto,
D.R.Pollard,
S.Senger,
G.P.Shah,
J.R.Toomey,
N.S.Watson,
H.E.Weston,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 2vh6:
The structure of Structure and Property Based Design of Factor Xa Inhibitors: Pyrrolidin-2-Ones with Biaryl P4 Motifs also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Structure and Property Based Design of Factor Xa Inhibitors: Pyrrolidin-2-Ones with Biaryl P4 Motifs
(pdb code 2vh6). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Structure and Property Based Design of Factor Xa Inhibitors: Pyrrolidin-2-Ones with Biaryl P4 Motifs, PDB code: 2vh6: Fluorine binding site 1 out of 1 in 2vh6Go back to Fluorine Binding Sites List in 2vh6
Fluorine binding site 1 out
of 1 in the Structure and Property Based Design of Factor Xa Inhibitors: Pyrrolidin-2-Ones with Biaryl P4 Motifs
Mono view Stereo pair view
Reference:
R.J.Young,
A.D.Borthwick,
D.Brown,
C.L.Burns-Kurtis,
M.Campbell,
C.Chan,
M.Charbaut,
C.W.Chung,
M.A.Convery,
H.A.Kelly,
N.Paul King,
S.Kleanthous,
A.M.Mason,
A.J.Pateman,
A.N.Patikis,
I.L.Pinto,
D.R.Pollard,
S.Senger,
G.P.Shah,
J.R.Toomey,
N.S.Watson,
H.E.Weston.
Structure and Property Based Design of Factor Xa Inhibitors: Pyrrolidin-2-Ones with Biaryl P4 Motifs. Bioorg.Med.Chem.Lett. V. 18 23 2008.
Page generated: Sun Dec 13 11:40:30 2020
ISSN: ISSN 0960-894X PubMed: 18054228 DOI: 10.1016/J.BMCL.2007.11.023 |
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