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Atomistry » Fluorine » PDB 2weg-2x2f » 2wu6 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 2weg-2x2f » 2wu6 » |
Fluorine in PDB 2wu6: Crystal Structure of the Human CLK3 in Complex with DkiEnzymatic activity of Crystal Structure of the Human CLK3 in Complex with Dki
All present enzymatic activity of Crystal Structure of the Human CLK3 in Complex with Dki:
2.7.12.1; Protein crystallography data
The structure of Crystal Structure of the Human CLK3 in Complex with Dki, PDB code: 2wu6
was solved by
J.R.C.Muniz,
O.Fedorov,
O.King,
P.Filippakopoulos,
A.N.Bullock,
C.Phillips,
T.Heightman,
E.Ugochukwu,
F.Von Delft,
C.H.Arrowsmith,
A.M.Edwards,
J.Weigelt,
C.Bountra,
S.Knapp,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 2wu6:
The structure of Crystal Structure of the Human CLK3 in Complex with Dki also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of the Human CLK3 in Complex with Dki
(pdb code 2wu6). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the Crystal Structure of the Human CLK3 in Complex with Dki, PDB code: 2wu6: Jump to Fluorine binding site number: 1; 2; Fluorine binding site 1 out of 2 in 2wu6Go back to Fluorine Binding Sites List in 2wu6
Fluorine binding site 1 out
of 2 in the Crystal Structure of the Human CLK3 in Complex with Dki
Mono view Stereo pair view
Fluorine binding site 2 out of 2 in 2wu6Go back to Fluorine Binding Sites List in 2wu6
Fluorine binding site 2 out
of 2 in the Crystal Structure of the Human CLK3 in Complex with Dki
Mono view Stereo pair view
Reference:
O.Fedorov,
K.Huber,
A.Eisenreich,
P.Filippakopoulos,
O.King,
A.N.Bullock,
D.Szklarczyk,
L.J.Jensen,
D.Fabbro,
J.Trappe,
U.Rauch,
F.Bracher,
S.Knapp.
Specific Clk Inhibitors From A Novel Chemotype For Regulation of Alternative Splicing. Chem.Biol V. 18 67 2011.
Page generated: Sun Dec 13 11:41:09 2020
ISSN: ISSN 1074-5521 PubMed: 21276940 DOI: 10.1016/J.CHEMBIOL.2010.11.009 |
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