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Atomistry » Fluorine » PDB 2weg-2x2f » 2wxg » |
Fluorine in PDB 2wxg: The Crystal Structure of the Murine Class Ia Pi 3-Kinase P110DELTA in Complex with SW13.Enzymatic activity of The Crystal Structure of the Murine Class Ia Pi 3-Kinase P110DELTA in Complex with SW13.
All present enzymatic activity of The Crystal Structure of the Murine Class Ia Pi 3-Kinase P110DELTA in Complex with SW13.:
2.7.1.153; Protein crystallography data
The structure of The Crystal Structure of the Murine Class Ia Pi 3-Kinase P110DELTA in Complex with SW13., PDB code: 2wxg
was solved by
A.Berndt,
S.Miller,
O.Williams,
D.D.Lee,
B.T.Houseman,
J.I.Pacold,
F.Gorrec,
W.-C.Hon,
Y.Liu,
C.Rommel,
P.Gaillard,
T.Ruckle,
M.K.Schwarz,
K.M.Shokat,
J.P.Shaw,
R.L.Williams,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the The Crystal Structure of the Murine Class Ia Pi 3-Kinase P110DELTA in Complex with SW13.
(pdb code 2wxg). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the The Crystal Structure of the Murine Class Ia Pi 3-Kinase P110DELTA in Complex with SW13., PDB code: 2wxg: Fluorine binding site 1 out of 1 in 2wxgGo back to Fluorine Binding Sites List in 2wxg
Fluorine binding site 1 out
of 1 in the The Crystal Structure of the Murine Class Ia Pi 3-Kinase P110DELTA in Complex with SW13.
Mono view Stereo pair view
Reference:
A.Berndt,
S.Miller,
O.Williams,
D.D.Lee,
B.T.Houseman,
J.I.Pacold,
F.Gorrec,
W.-C.Hon,
Y.Liu,
C.Rommel,
P.Gaillard,
T.Ruckle,
M.K.Schwarz,
K.M.Shokat,
J.P.Shaw,
R.L.Williams.
The P110D Structure: Mechanisms For Selectivity and Potency of New Pi(3)K Inhibitors Nat.Chem.Biol. V. 6 117 2010.
Page generated: Wed Jul 31 16:29:10 2024
ISSN: ISSN 1552-4450 PubMed: 20081827 DOI: 10.1038/NCHEMBIO.293 |
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