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Atomistry » Fluorine » PDB 2weg-2x2f » 2wxo » |
Fluorine in PDB 2wxo: The Crystal Structure of the Murine Class Ia Pi 3-Kinase P110DELTA in Complex with AS5.Enzymatic activity of The Crystal Structure of the Murine Class Ia Pi 3-Kinase P110DELTA in Complex with AS5.
All present enzymatic activity of The Crystal Structure of the Murine Class Ia Pi 3-Kinase P110DELTA in Complex with AS5.:
2.7.1.153; Protein crystallography data
The structure of The Crystal Structure of the Murine Class Ia Pi 3-Kinase P110DELTA in Complex with AS5., PDB code: 2wxo
was solved by
A.Berndt,
S.Miller,
O.Williams,
D.D.Lee,
B.T.Houseman,
J.I.Pacold,
F.Gorrec,
W.-C.Hon,
Y.Liu,
C.Rommel,
P.Gaillard,
T.Ruckle,
M.K.Schwarz,
K.M.Shokat,
J.P.Shaw,
R.L.Williams,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the The Crystal Structure of the Murine Class Ia Pi 3-Kinase P110DELTA in Complex with AS5.
(pdb code 2wxo). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the The Crystal Structure of the Murine Class Ia Pi 3-Kinase P110DELTA in Complex with AS5., PDB code: 2wxo: Fluorine binding site 1 out of 1 in 2wxoGo back to Fluorine Binding Sites List in 2wxo
Fluorine binding site 1 out
of 1 in the The Crystal Structure of the Murine Class Ia Pi 3-Kinase P110DELTA in Complex with AS5.
Mono view Stereo pair view
Reference:
A.Berndt,
S.Miller,
O.Williams,
D.D.Lee,
B.T.Houseman,
J.I.Pacold,
F.Gorrec,
W.-C.Hon,
Y.Liu,
C.Rommel,
P.Gaillard,
T.Ruckle,
M.K.Schwarz,
K.M.Shokat,
J.P.Shaw,
R.L.Williams.
The P110D Structure: Mechanisms For Selectivity and Potency of New Pi(3)K Inhibitors Nat.Chem.Biol. V. 6 117 2010.
Page generated: Sun Dec 13 11:41:17 2020
ISSN: ISSN 1552-4450 PubMed: 20081827 DOI: 10.1038/NCHEMBIO.293 |
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