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Atomistry » Fluorine » PDB 2weg-2x2f » 2wzd | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 2weg-2x2f » 2wzd » |
Fluorine in PDB 2wzd: The Catalytically Active Fully Closed Conformation of Human Phosphoglycerate Kinase K219A Mutant in Complex with Adp, 3PG and Aluminium TrifluorideEnzymatic activity of The Catalytically Active Fully Closed Conformation of Human Phosphoglycerate Kinase K219A Mutant in Complex with Adp, 3PG and Aluminium Trifluoride
All present enzymatic activity of The Catalytically Active Fully Closed Conformation of Human Phosphoglycerate Kinase K219A Mutant in Complex with Adp, 3PG and Aluminium Trifluoride:
2.7.2.3; Protein crystallography data
The structure of The Catalytically Active Fully Closed Conformation of Human Phosphoglycerate Kinase K219A Mutant in Complex with Adp, 3PG and Aluminium Trifluoride, PDB code: 2wzd
was solved by
M.W.Bowler,
M.J.Cliff,
J.P.M.Marston,
N.J.Baxter,
A.M.H.Hownslow,
A.V.Varga,
J.Szabo,
M.Vas,
G.M.Blackburn,
J.P.Waltho,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 2wzd:
The structure of The Catalytically Active Fully Closed Conformation of Human Phosphoglycerate Kinase K219A Mutant in Complex with Adp, 3PG and Aluminium Trifluoride also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the The Catalytically Active Fully Closed Conformation of Human Phosphoglycerate Kinase K219A Mutant in Complex with Adp, 3PG and Aluminium Trifluoride
(pdb code 2wzd). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 3 binding sites of Fluorine where determined in the The Catalytically Active Fully Closed Conformation of Human Phosphoglycerate Kinase K219A Mutant in Complex with Adp, 3PG and Aluminium Trifluoride, PDB code: 2wzd: Jump to Fluorine binding site number: 1; 2; 3; Fluorine binding site 1 out of 3 in 2wzdGo back to Fluorine Binding Sites List in 2wzd
Fluorine binding site 1 out
of 3 in the The Catalytically Active Fully Closed Conformation of Human Phosphoglycerate Kinase K219A Mutant in Complex with Adp, 3PG and Aluminium Trifluoride
Mono view Stereo pair view
Fluorine binding site 2 out of 3 in 2wzdGo back to Fluorine Binding Sites List in 2wzd
Fluorine binding site 2 out
of 3 in the The Catalytically Active Fully Closed Conformation of Human Phosphoglycerate Kinase K219A Mutant in Complex with Adp, 3PG and Aluminium Trifluoride
Mono view Stereo pair view
Fluorine binding site 3 out of 3 in 2wzdGo back to Fluorine Binding Sites List in 2wzd
Fluorine binding site 3 out
of 3 in the The Catalytically Active Fully Closed Conformation of Human Phosphoglycerate Kinase K219A Mutant in Complex with Adp, 3PG and Aluminium Trifluoride
Mono view Stereo pair view
Reference:
M.J.Cliff,
M.W.Bowler,
J.Szabo,
J.P.M.Marston,
A.V.Varga,
A.M.H.Hownslow,
N.J.Baxter,
G.M.Blackburn,
M.Vas,
J.P.Waltho.
Transition State Analogue Structures of Human Phosphoglycerate Kinase Establish the Importance of Charge Balance in Catalysis. J.Am.Chem.Soc. V. 132 6507 2010.
Page generated: Sun Dec 13 11:41:22 2020
ISSN: ISSN 0002-7863 PubMed: 20397725 DOI: 10.1021/JA100974T |
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