|
Atomistry » Fluorine » PDB 2x2n-2y1w » 2xbj | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 2x2n-2y1w » 2xbj » |
Fluorine in PDB 2xbj: Crystal Structure of CHK2 in Complex with An InhibitorEnzymatic activity of Crystal Structure of CHK2 in Complex with An Inhibitor
All present enzymatic activity of Crystal Structure of CHK2 in Complex with An Inhibitor:
2.7.11.1; Protein crystallography data
The structure of Crystal Structure of CHK2 in Complex with An Inhibitor, PDB code: 2xbj
was solved by
V.E.Anderson,
M.I.Walton,
P.D.Eve,
J.J.Caldwell,
L.H.Pearl,
A.W.Oliver,
I.Collins,
M.D.Garrett,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 2xbj:
The structure of Crystal Structure of CHK2 in Complex with An Inhibitor also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of CHK2 in Complex with An Inhibitor
(pdb code 2xbj). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Crystal Structure of CHK2 in Complex with An Inhibitor, PDB code: 2xbj: Fluorine binding site 1 out of 1 in 2xbjGo back to Fluorine Binding Sites List in 2xbj
Fluorine binding site 1 out
of 1 in the Crystal Structure of CHK2 in Complex with An Inhibitor
Mono view Stereo pair view
Reference:
J.J.Caldwell,
E.J.Welsh,
C.Matijssen,
V.E.Anderson,
L.Antoni,
K.Boxall,
F.Urban,
A.Hayes,
F.I.Raynaud,
L.J.Rigoreau,
T.Raynham,
G.W.Aherne,
L.H.Pearl,
A.W.Oliver,
M.D.Garrett,
I.Collins.
Structure-Based Design of Potent and Selective 2- (Quinazolin-2-Yl)Phenol Inhibitors of Checkpoint Kinase 2. J.Med.Chem. V. 54 580 2011.
Page generated: Sun Dec 13 11:41:33 2020
ISSN: ISSN 0022-2623 PubMed: 21186793 DOI: 10.1021/JM101150B |
Last articlesZn in 8WB0Zn in 8WAX Zn in 8WAU Zn in 8WAZ Zn in 8WAY Zn in 8WAV Zn in 8WAW Zn in 8WAT Zn in 8W7M Zn in 8WD3 |
© Copyright 2008-2020 by atomistry.com | ||
Home | Site Map | Copyright | Contact us | Privacy |