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Atomistry » Fluorine » PDB 2y1x-2z5z » 2y2j » |
Fluorine in PDB 2y2j: Penicillin-Binding Protein 1B (Pbp-1B) in Complex with An Alkyl Boronate (ZA4)Enzymatic activity of Penicillin-Binding Protein 1B (Pbp-1B) in Complex with An Alkyl Boronate (ZA4)
All present enzymatic activity of Penicillin-Binding Protein 1B (Pbp-1B) in Complex with An Alkyl Boronate (ZA4):
2.4.1.129; Protein crystallography data
The structure of Penicillin-Binding Protein 1B (Pbp-1B) in Complex with An Alkyl Boronate (ZA4), PDB code: 2y2j
was solved by
C.Contreras-Martel,
A.Amoroso,
E.C.Woon,
A.Zervosen,
S.Inglis,
A.Martins,
O.Verlaine,
A.Rydzik,
V.Job,
A.Luxen,
B.Joris,
C.J.Schofield,
A.Dessen,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 2y2j:
The structure of Penicillin-Binding Protein 1B (Pbp-1B) in Complex with An Alkyl Boronate (ZA4) also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Penicillin-Binding Protein 1B (Pbp-1B) in Complex with An Alkyl Boronate (ZA4)
(pdb code 2y2j). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Penicillin-Binding Protein 1B (Pbp-1B) in Complex with An Alkyl Boronate (ZA4), PDB code: 2y2j: Fluorine binding site 1 out of 1 in 2y2jGo back to Fluorine Binding Sites List in 2y2j
Fluorine binding site 1 out
of 1 in the Penicillin-Binding Protein 1B (Pbp-1B) in Complex with An Alkyl Boronate (ZA4)
Mono view Stereo pair view
Reference:
C.Contreras-Martel,
A.Amoroso,
E.C.Woon,
A.Zervosen,
S.Inglis,
A.Martins,
O.Verlaine,
A.Rydzik,
V.Job,
A.Luxen,
B.Joris,
C.J.Schofield,
A.Dessen.
Structure-Guided Design of Cell Wall Biosynthesis Inhibitors That Overcome Beta-Lactam Resistance in Staphylococcus Aureus (Mrsa). Acs Chem.Biol V. 6 943 2011.
Page generated: Sun Dec 13 11:42:04 2020
ISSN: ISSN 1554-8929 PubMed: 21732689 DOI: 10.1021/CB2001846 |
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