Fluorine in PDB 3bl7: Synthetic Gene Encoded Dcps Bound to Inhibitor DG156844

The structure of Synthetic Gene Encoded Dcps Bound to Inhibitor DG156844, PDB code: 3bl7 was solved by B.L.Staker, J.Christensen, L.Stewart, Accelerated Technologiescenter For Gene To 3D Structure (Atcg3D), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	28.95 / 2.31
Space group	P 1
Cell size a, b, c (Å), α, β, γ (°)	49.257, 56.271, 60.334, 118.81, 92.39, 99.99
R / Rfree (%)	21.1 / 27.6

The binding sites of Fluorine atom in the Synthetic Gene Encoded Dcps Bound to Inhibitor DG156844 (pdb code 3bl7). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Synthetic Gene Encoded Dcps Bound to Inhibitor DG156844, PDB code: 3bl7:

Fluorine binding site 1 out of 1 in the Synthetic Gene Encoded Dcps Bound to Inhibitor DG156844


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Synthetic Gene Encoded Dcps Bound to Inhibitor DG156844 within 5.0Å range: probe atom residue distance (Å) B Occ A:F901 b:28.2 occ:1.00 F58 A:DD1901 0.0 28.2 1.0 C1 A:DD1901 1.3 27.8 1.0 C6 A:DD1901 2.4 27.1 1.0 C2 A:DD1901 2.5 27.3 1.0 OG A:SER272 3.0 13.0 1.0 C13 A:DD1901 3.0 27.1 1.0 C21 A:DD1901 3.2 23.9 1.0 CB A:SER272 3.4 12.6 1.0 N15 A:DD1901 3.5 25.3 1.0 CE A:LYS142 3.5 27.9 1.0 C5 A:DD1901 3.6 27.4 1.0 C3 A:DD1901 3.7 28.0 1.0 C4 A:DD1901 4.1 27.7 1.0 CD A:LYS142 4.2 27.7 1.0 CG A:LYS142 4.3 27.4 1.0 CA A:SER272 4.4 12.6 1.0 C20 A:DD1901 4.6 22.6 1.0 NZ A:LYS142 4.7 28.4 1.0 C17 A:DD1901 4.8 24.6 1.0 O A:SER272 5.0 13.0 1.0

J.Singh, M.Salcius, S.W.Liu, B.L.Staker, R.Mishra, J.Thurmond, G.Michaud, D.R.Mattoon, J.Printen, J.Christensen, J.M.Bjornsson, B.A.Pollok, M.Kiledjian, L.Stewart, J.Jarecki, M.E.Gurney. Dcps As A Therapeutic Target For Spinal Muscular Atrophy. Acs Chem.Biol. V. 3 711 2008.
ISSN: ISSN 1554-8929
PubMed: 18839960
DOI: 10.1021/CB800120T