Fluorine in PDB 3c7k: Molecular Architecture of Galphao and the Structural Basis For RGS16- Mediated Deactivation
Protein crystallography data
The structure of Molecular Architecture of Galphao and the Structural Basis For RGS16- Mediated Deactivation, PDB code: 3c7k
was solved by
K.C.Slep,
M.A.Kercher,
T.Wieland,
C.Chen,
M.I.Simon,
P.B.Sigler,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Resolution Low / High (Å)
|
50.00 /
2.90
|
Space group
|
P 32 2 1
|
Cell size a, b, c (Å), α, β, γ (°)
|
96.357,
96.357,
235.610,
90.00,
90.00,
120.00
|
R / Rfree (%)
|
25 /
31.1
|
Other elements in 3c7k:
The structure of Molecular Architecture of Galphao and the Structural Basis For RGS16- Mediated Deactivation also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Molecular Architecture of Galphao and the Structural Basis For RGS16- Mediated Deactivation
(pdb code 3c7k). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 8 binding sites of Fluorine where determined in the
Molecular Architecture of Galphao and the Structural Basis For RGS16- Mediated Deactivation, PDB code: 3c7k:
Jump to Fluorine binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
Fluorine binding site 1 out
of 8 in 3c7k
Go back to
Fluorine Binding Sites List in 3c7k
Fluorine binding site 1 out
of 8 in the Molecular Architecture of Galphao and the Structural Basis For RGS16- Mediated Deactivation
Mono view
Stereo pair view
|
A full contact list of Fluorine with other atoms in the F binding
site number 1 of Molecular Architecture of Galphao and the Structural Basis For RGS16- Mediated Deactivation within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:F365
b:15.6
occ:1.00
|
F1
|
A:ALF365
|
0.0
|
15.6
|
1.0
|
AL
|
A:ALF365
|
1.8
|
15.8
|
1.0
|
F3
|
A:ALF365
|
2.5
|
15.5
|
1.0
|
F4
|
A:ALF365
|
2.5
|
16.9
|
1.0
|
NH2
|
A:ARG179
|
2.5
|
67.1
|
1.0
|
O
|
A:HOH401
|
2.8
|
0.3
|
1.0
|
NH1
|
A:ARG179
|
2.8
|
64.6
|
1.0
|
O3B
|
A:GDP361
|
2.8
|
14.5
|
1.0
|
NE2
|
A:GLN205
|
2.9
|
63.9
|
1.0
|
CZ
|
A:ARG179
|
3.1
|
65.0
|
1.0
|
N
|
A:GLU43
|
3.3
|
75.8
|
1.0
|
F2
|
A:ALF365
|
3.6
|
16.8
|
1.0
|
CD
|
A:GLN205
|
3.7
|
63.4
|
1.0
|
OE1
|
A:GLN205
|
3.7
|
63.2
|
1.0
|
CG
|
A:GLU43
|
3.9
|
76.9
|
1.0
|
CG
|
A:LYS181
|
4.0
|
70.1
|
1.0
|
CA
|
A:GLU43
|
4.0
|
76.0
|
1.0
|
PB
|
A:GDP361
|
4.1
|
15.1
|
1.0
|
CA
|
A:LYS181
|
4.2
|
68.2
|
1.0
|
CA
|
A:GLY42
|
4.2
|
74.2
|
1.0
|
C
|
A:GLY42
|
4.2
|
75.3
|
1.0
|
O2B
|
A:GDP361
|
4.2
|
14.0
|
1.0
|
NE
|
A:ARG179
|
4.4
|
63.4
|
1.0
|
CB
|
A:LYS181
|
4.4
|
68.5
|
1.0
|
CD
|
A:LYS181
|
4.4
|
68.9
|
1.0
|
CB
|
A:GLU43
|
4.6
|
75.5
|
1.0
|
N
|
A:THR182
|
4.6
|
68.8
|
1.0
|
MG
|
A:MG362
|
4.7
|
18.9
|
1.0
|
O1B
|
A:GDP361
|
4.8
|
15.3
|
1.0
|
NZ
|
A:LYS46
|
4.9
|
69.8
|
1.0
|
OE2
|
A:GLU43
|
4.9
|
77.7
|
1.0
|
N
|
A:GLY204
|
5.0
|
80.3
|
1.0
|
C
|
A:LYS181
|
5.0
|
67.9
|
1.0
|
O3A
|
A:GDP361
|
5.0
|
16.9
|
1.0
|
|
Fluorine binding site 2 out
of 8 in 3c7k
Go back to
Fluorine Binding Sites List in 3c7k
Fluorine binding site 2 out
of 8 in the Molecular Architecture of Galphao and the Structural Basis For RGS16- Mediated Deactivation
Mono view
Stereo pair view
|
A full contact list of Fluorine with other atoms in the F binding
site number 2 of Molecular Architecture of Galphao and the Structural Basis For RGS16- Mediated Deactivation within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:F365
b:16.8
occ:1.00
|
F2
|
A:ALF365
|
0.0
|
16.8
|
1.0
|
AL
|
A:ALF365
|
1.8
|
15.8
|
1.0
|
MG
|
A:MG362
|
2.3
|
18.9
|
1.0
|
F3
|
A:ALF365
|
2.5
|
15.5
|
1.0
|
F4
|
A:ALF365
|
2.5
|
16.9
|
1.0
|
O
|
A:HOH401
|
2.7
|
0.3
|
1.0
|
O1B
|
A:GDP361
|
2.8
|
15.3
|
1.0
|
O
|
A:HOH403
|
2.8
|
79.8
|
1.0
|
PB
|
A:GDP361
|
3.0
|
15.1
|
1.0
|
O2B
|
A:GDP361
|
3.0
|
14.0
|
1.0
|
NZ
|
A:LYS46
|
3.0
|
69.8
|
1.0
|
CE
|
A:LYS46
|
3.1
|
71.4
|
1.0
|
O
|
A:VAL202
|
3.3
|
89.3
|
1.0
|
O3B
|
A:GDP361
|
3.3
|
14.5
|
1.0
|
F1
|
A:ALF365
|
3.6
|
15.6
|
1.0
|
CB
|
A:THR182
|
3.8
|
70.0
|
1.0
|
N
|
A:GLY204
|
3.8
|
80.3
|
1.0
|
OG1
|
A:THR182
|
3.9
|
68.7
|
1.0
|
CA
|
A:GLY203
|
4.2
|
84.7
|
1.0
|
N
|
A:THR182
|
4.3
|
68.8
|
1.0
|
C
|
A:VAL202
|
4.4
|
89.7
|
1.0
|
C
|
A:GLY203
|
4.5
|
82.0
|
1.0
|
OG
|
A:SER47
|
4.5
|
80.4
|
1.0
|
O
|
A:THR182
|
4.5
|
71.6
|
1.0
|
CD
|
A:LYS46
|
4.6
|
73.6
|
1.0
|
CA
|
A:THR182
|
4.6
|
70.3
|
1.0
|
O3A
|
A:GDP361
|
4.6
|
16.9
|
1.0
|
O
|
A:HOH402
|
4.6
|
78.7
|
1.0
|
CB
|
A:LYS46
|
4.7
|
78.6
|
1.0
|
CA
|
A:GLY204
|
4.7
|
77.4
|
1.0
|
N
|
A:GLY203
|
4.8
|
88.3
|
1.0
|
CG2
|
A:THR182
|
4.8
|
69.7
|
1.0
|
NH1
|
A:ARG179
|
4.9
|
64.6
|
1.0
|
|
Fluorine binding site 3 out
of 8 in 3c7k
Go back to
Fluorine Binding Sites List in 3c7k
Fluorine binding site 3 out
of 8 in the Molecular Architecture of Galphao and the Structural Basis For RGS16- Mediated Deactivation
Mono view
Stereo pair view
|
A full contact list of Fluorine with other atoms in the F binding
site number 3 of Molecular Architecture of Galphao and the Structural Basis For RGS16- Mediated Deactivation within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:F365
b:15.5
occ:1.00
|
F3
|
A:ALF365
|
0.0
|
15.5
|
1.0
|
AL
|
A:ALF365
|
1.8
|
15.8
|
1.0
|
F2
|
A:ALF365
|
2.5
|
16.8
|
1.0
|
F1
|
A:ALF365
|
2.5
|
15.6
|
1.0
|
NZ
|
A:LYS46
|
2.7
|
69.8
|
1.0
|
O
|
A:HOH401
|
2.7
|
0.3
|
1.0
|
O3B
|
A:GDP361
|
2.9
|
14.5
|
1.0
|
N
|
A:GLY204
|
3.1
|
80.3
|
1.0
|
CA
|
A:GLY42
|
3.1
|
74.2
|
1.0
|
N
|
A:GLU43
|
3.1
|
75.8
|
1.0
|
CA
|
A:GLY204
|
3.3
|
77.4
|
1.0
|
NE2
|
A:GLN205
|
3.4
|
63.9
|
1.0
|
O
|
A:ALA41
|
3.4
|
74.0
|
1.0
|
C
|
A:GLY42
|
3.6
|
75.3
|
1.0
|
CE
|
A:LYS46
|
3.6
|
71.4
|
1.0
|
O1B
|
A:GDP361
|
3.6
|
15.3
|
1.0
|
F4
|
A:ALF365
|
3.6
|
16.9
|
1.0
|
PB
|
A:GDP361
|
3.7
|
15.1
|
1.0
|
N
|
A:GLY42
|
4.0
|
74.3
|
1.0
|
C
|
A:ALA41
|
4.1
|
74.2
|
1.0
|
CD
|
A:GLN205
|
4.1
|
63.4
|
1.0
|
OE1
|
A:GLN205
|
4.2
|
63.2
|
1.0
|
C
|
A:GLY204
|
4.2
|
75.1
|
1.0
|
CA
|
A:GLU43
|
4.2
|
76.0
|
1.0
|
C
|
A:GLY203
|
4.3
|
82.0
|
1.0
|
N
|
A:GLN205
|
4.3
|
72.5
|
1.0
|
O2B
|
A:GDP361
|
4.4
|
14.0
|
1.0
|
MG
|
A:MG362
|
4.6
|
18.9
|
1.0
|
NH1
|
A:ARG179
|
4.7
|
64.6
|
1.0
|
O
|
A:GLY42
|
4.7
|
76.5
|
1.0
|
CA
|
A:GLY203
|
4.8
|
84.7
|
1.0
|
N
|
A:SER44
|
4.8
|
77.2
|
1.0
|
CD
|
A:LYS46
|
4.9
|
73.6
|
1.0
|
O3A
|
A:GDP361
|
5.0
|
16.9
|
1.0
|
|
Fluorine binding site 4 out
of 8 in 3c7k
Go back to
Fluorine Binding Sites List in 3c7k
Fluorine binding site 4 out
of 8 in the Molecular Architecture of Galphao and the Structural Basis For RGS16- Mediated Deactivation
Mono view
Stereo pair view
|
A full contact list of Fluorine with other atoms in the F binding
site number 4 of Molecular Architecture of Galphao and the Structural Basis For RGS16- Mediated Deactivation within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:F365
b:16.9
occ:1.00
|
F4
|
A:ALF365
|
0.0
|
16.9
|
1.0
|
AL
|
A:ALF365
|
1.8
|
15.8
|
1.0
|
MG
|
A:MG362
|
2.5
|
18.9
|
1.0
|
F2
|
A:ALF365
|
2.5
|
16.8
|
1.0
|
F1
|
A:ALF365
|
2.5
|
15.6
|
1.0
|
O2B
|
A:GDP361
|
2.7
|
14.0
|
1.0
|
N
|
A:THR182
|
2.7
|
68.8
|
1.0
|
O
|
A:HOH401
|
2.8
|
0.3
|
1.0
|
NH1
|
A:ARG179
|
3.1
|
64.6
|
1.0
|
CA
|
A:LYS181
|
3.2
|
68.2
|
1.0
|
O3B
|
A:GDP361
|
3.3
|
14.5
|
1.0
|
PB
|
A:GDP361
|
3.4
|
15.1
|
1.0
|
C
|
A:LYS181
|
3.4
|
67.9
|
1.0
|
OG1
|
A:THR182
|
3.5
|
68.7
|
1.0
|
NH2
|
A:ARG179
|
3.6
|
67.1
|
1.0
|
O
|
A:HOH402
|
3.6
|
78.7
|
1.0
|
F3
|
A:ALF365
|
3.6
|
15.5
|
1.0
|
CZ
|
A:ARG179
|
3.7
|
65.0
|
1.0
|
CB
|
A:THR182
|
3.7
|
70.0
|
1.0
|
O
|
A:VAL180
|
3.7
|
69.4
|
1.0
|
CA
|
A:THR182
|
3.8
|
70.3
|
1.0
|
N
|
A:LYS181
|
4.0
|
69.5
|
1.0
|
C
|
A:VAL180
|
4.2
|
68.8
|
1.0
|
CB
|
A:LYS181
|
4.2
|
68.5
|
1.0
|
CG
|
A:LYS181
|
4.2
|
70.1
|
1.0
|
O2A
|
A:GDP361
|
4.2
|
13.4
|
1.0
|
O1B
|
A:GDP361
|
4.3
|
15.3
|
1.0
|
O
|
A:THR182
|
4.4
|
71.6
|
1.0
|
O
|
A:HOH403
|
4.6
|
79.8
|
1.0
|
O3A
|
A:GDP361
|
4.6
|
16.9
|
1.0
|
C
|
A:THR182
|
4.6
|
71.1
|
1.0
|
O
|
A:LYS181
|
4.7
|
66.8
|
1.0
|
NE
|
A:ARG179
|
4.8
|
63.4
|
1.0
|
OG
|
A:SER47
|
5.0
|
80.4
|
1.0
|
|
Fluorine binding site 5 out
of 8 in 3c7k
Go back to
Fluorine Binding Sites List in 3c7k
Fluorine binding site 5 out
of 8 in the Molecular Architecture of Galphao and the Structural Basis For RGS16- Mediated Deactivation
Mono view
Stereo pair view
|
A full contact list of Fluorine with other atoms in the F binding
site number 5 of Molecular Architecture of Galphao and the Structural Basis For RGS16- Mediated Deactivation within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:F365
b:57.7
occ:1.00
|
F1
|
C:ALF365
|
0.0
|
57.7
|
1.0
|
AL
|
C:ALF365
|
1.7
|
57.9
|
1.0
|
F4
|
C:ALF365
|
2.4
|
60.9
|
1.0
|
F3
|
C:ALF365
|
2.6
|
49.9
|
1.0
|
N
|
C:THR182
|
2.7
|
75.9
|
1.0
|
O
|
C:HOH401
|
2.8
|
0.3
|
1.0
|
O
|
C:HOH402
|
2.9
|
78.7
|
1.0
|
MG
|
C:MG362
|
3.0
|
71.2
|
1.0
|
NH1
|
C:ARG179
|
3.1
|
66.2
|
1.0
|
O3B
|
C:GDP361
|
3.2
|
14.5
|
1.0
|
CA
|
C:LYS181
|
3.3
|
75.9
|
1.0
|
O2B
|
C:GDP361
|
3.4
|
14.0
|
1.0
|
O
|
C:VAL180
|
3.5
|
74.7
|
1.0
|
C
|
C:LYS181
|
3.5
|
75.7
|
1.0
|
F2
|
C:ALF365
|
3.5
|
58.8
|
1.0
|
CB
|
C:THR182
|
3.5
|
77.2
|
1.0
|
CA
|
C:THR182
|
3.6
|
77.8
|
1.0
|
OG1
|
C:THR182
|
3.7
|
76.9
|
1.0
|
CZ
|
C:ARG179
|
3.8
|
65.4
|
1.0
|
NH2
|
C:ARG179
|
3.8
|
64.8
|
1.0
|
PB
|
C:GDP361
|
3.9
|
15.1
|
1.0
|
N
|
C:LYS181
|
4.1
|
75.3
|
1.0
|
CG
|
C:LYS181
|
4.2
|
77.5
|
1.0
|
C
|
C:VAL180
|
4.2
|
75.4
|
1.0
|
CB
|
C:LYS181
|
4.2
|
76.5
|
1.0
|
O2A
|
C:GDP361
|
4.2
|
13.4
|
1.0
|
O
|
C:THR182
|
4.3
|
80.3
|
1.0
|
C
|
C:THR182
|
4.5
|
78.2
|
1.0
|
O
|
C:HOH403
|
4.6
|
79.8
|
1.0
|
O
|
C:LYS181
|
4.7
|
75.5
|
1.0
|
NE
|
C:ARG179
|
4.8
|
65.8
|
1.0
|
O3A
|
C:GDP361
|
4.9
|
16.9
|
1.0
|
CG2
|
C:THR182
|
5.0
|
76.7
|
1.0
|
OE1
|
C:GLN205
|
5.0
|
68.5
|
1.0
|
|
Fluorine binding site 6 out
of 8 in 3c7k
Go back to
Fluorine Binding Sites List in 3c7k
Fluorine binding site 6 out
of 8 in the Molecular Architecture of Galphao and the Structural Basis For RGS16- Mediated Deactivation
Mono view
Stereo pair view
|
A full contact list of Fluorine with other atoms in the F binding
site number 6 of Molecular Architecture of Galphao and the Structural Basis For RGS16- Mediated Deactivation within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:F365
b:58.8
occ:1.00
|
F2
|
C:ALF365
|
0.0
|
58.8
|
1.0
|
AL
|
C:ALF365
|
1.8
|
57.9
|
1.0
|
F3
|
C:ALF365
|
2.5
|
49.9
|
1.0
|
F4
|
C:ALF365
|
2.5
|
60.9
|
1.0
|
NZ
|
C:LYS46
|
2.7
|
70.7
|
1.0
|
O
|
C:HOH401
|
2.8
|
0.3
|
1.0
|
N
|
C:GLY204
|
3.0
|
79.0
|
1.0
|
O3B
|
C:GDP361
|
3.1
|
14.5
|
1.0
|
N
|
C:GLU43
|
3.2
|
76.2
|
1.0
|
CA
|
C:GLY204
|
3.2
|
76.5
|
1.0
|
CA
|
C:GLY42
|
3.3
|
74.3
|
1.0
|
F1
|
C:ALF365
|
3.5
|
57.7
|
1.0
|
C
|
C:GLY42
|
3.5
|
75.3
|
1.0
|
CE
|
C:LYS46
|
3.7
|
72.3
|
1.0
|
OE1
|
C:GLN205
|
3.8
|
68.5
|
1.0
|
NE2
|
C:GLN205
|
3.9
|
70.8
|
1.0
|
PB
|
C:GDP361
|
4.0
|
15.1
|
1.0
|
O
|
C:ALA41
|
4.0
|
73.4
|
1.0
|
O1B
|
C:GDP361
|
4.0
|
15.3
|
1.0
|
CA
|
C:GLU43
|
4.2
|
76.5
|
1.0
|
C
|
C:GLY203
|
4.2
|
81.9
|
1.0
|
CD
|
C:GLN205
|
4.2
|
68.8
|
1.0
|
C
|
C:GLY204
|
4.2
|
73.8
|
1.0
|
N
|
C:GLN205
|
4.2
|
71.4
|
1.0
|
N
|
C:GLY42
|
4.3
|
74.8
|
1.0
|
O2B
|
C:GDP361
|
4.5
|
14.0
|
1.0
|
C
|
C:ALA41
|
4.6
|
74.4
|
1.0
|
O
|
C:GLY42
|
4.6
|
76.9
|
1.0
|
CA
|
C:GLY203
|
4.7
|
84.5
|
1.0
|
NH1
|
C:ARG179
|
4.8
|
66.2
|
1.0
|
N
|
C:SER44
|
4.9
|
76.6
|
1.0
|
O
|
C:VAL202
|
4.9
|
90.0
|
1.0
|
MG
|
C:MG362
|
5.0
|
71.2
|
1.0
|
|
Fluorine binding site 7 out
of 8 in 3c7k
Go back to
Fluorine Binding Sites List in 3c7k
Fluorine binding site 7 out
of 8 in the Molecular Architecture of Galphao and the Structural Basis For RGS16- Mediated Deactivation
Mono view
Stereo pair view
|
A full contact list of Fluorine with other atoms in the F binding
site number 7 of Molecular Architecture of Galphao and the Structural Basis For RGS16- Mediated Deactivation within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:F365
b:49.9
occ:1.00
|
F3
|
C:ALF365
|
0.0
|
49.9
|
1.0
|
AL
|
C:ALF365
|
1.8
|
57.9
|
1.0
|
F2
|
C:ALF365
|
2.5
|
58.8
|
1.0
|
F1
|
C:ALF365
|
2.6
|
57.7
|
1.0
|
MG
|
C:MG362
|
2.7
|
71.2
|
1.0
|
O
|
C:HOH403
|
2.8
|
79.8
|
1.0
|
NZ
|
C:LYS46
|
2.9
|
70.7
|
1.0
|
O
|
C:HOH401
|
2.9
|
0.3
|
1.0
|
O2B
|
C:GDP361
|
3.2
|
14.0
|
1.0
|
CE
|
C:LYS46
|
3.2
|
72.3
|
1.0
|
O
|
C:VAL202
|
3.3
|
90.0
|
1.0
|
O3B
|
C:GDP361
|
3.3
|
14.5
|
1.0
|
PB
|
C:GDP361
|
3.5
|
15.1
|
1.0
|
F4
|
C:ALF365
|
3.6
|
60.9
|
1.0
|
CB
|
C:THR182
|
3.6
|
77.2
|
1.0
|
O1B
|
C:GDP361
|
3.7
|
15.3
|
1.0
|
N
|
C:GLY204
|
3.8
|
79.0
|
1.0
|
O
|
C:THR182
|
4.0
|
80.3
|
1.0
|
OG1
|
C:THR182
|
4.2
|
76.9
|
1.0
|
N
|
C:THR182
|
4.2
|
75.9
|
1.0
|
CA
|
C:GLY203
|
4.2
|
84.5
|
1.0
|
O
|
C:HOH402
|
4.3
|
78.7
|
1.0
|
CA
|
C:THR182
|
4.4
|
77.8
|
1.0
|
C
|
C:VAL202
|
4.4
|
90.3
|
1.0
|
CG2
|
C:THR182
|
4.4
|
76.7
|
1.0
|
C
|
C:GLY203
|
4.4
|
81.9
|
1.0
|
CA
|
C:GLY204
|
4.7
|
76.5
|
1.0
|
CD
|
C:LYS46
|
4.7
|
74.4
|
1.0
|
C
|
C:THR182
|
4.7
|
78.2
|
1.0
|
OD2
|
C:ASP201
|
4.8
|
99.4
|
1.0
|
N
|
C:GLY203
|
4.8
|
88.0
|
1.0
|
CB
|
C:LYS46
|
4.9
|
78.0
|
1.0
|
NH1
|
C:ARG179
|
5.0
|
66.2
|
1.0
|
|
Fluorine binding site 8 out
of 8 in 3c7k
Go back to
Fluorine Binding Sites List in 3c7k
Fluorine binding site 8 out
of 8 in the Molecular Architecture of Galphao and the Structural Basis For RGS16- Mediated Deactivation
Mono view
Stereo pair view
|
A full contact list of Fluorine with other atoms in the F binding
site number 8 of Molecular Architecture of Galphao and the Structural Basis For RGS16- Mediated Deactivation within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:F365
b:60.9
occ:1.00
|
F4
|
C:ALF365
|
0.0
|
60.9
|
1.0
|
AL
|
C:ALF365
|
1.7
|
57.9
|
1.0
|
F1
|
C:ALF365
|
2.4
|
57.7
|
1.0
|
F2
|
C:ALF365
|
2.5
|
58.8
|
1.0
|
NH2
|
C:ARG179
|
2.6
|
64.8
|
1.0
|
O
|
C:HOH401
|
2.8
|
0.3
|
1.0
|
O3B
|
C:GDP361
|
2.9
|
14.5
|
1.0
|
NH1
|
C:ARG179
|
2.9
|
66.2
|
1.0
|
CZ
|
C:ARG179
|
3.2
|
65.4
|
1.0
|
N
|
C:GLU43
|
3.5
|
76.2
|
1.0
|
F3
|
C:ALF365
|
3.6
|
49.9
|
1.0
|
NE2
|
C:GLN205
|
3.6
|
70.8
|
1.0
|
OE1
|
C:GLN205
|
3.6
|
68.5
|
1.0
|
CG
|
C:LYS181
|
4.0
|
77.5
|
1.0
|
CD
|
C:GLN205
|
4.0
|
68.8
|
1.0
|
CA
|
C:GLU43
|
4.0
|
76.5
|
1.0
|
CG
|
C:GLU43
|
4.1
|
77.3
|
1.0
|
CA
|
C:LYS181
|
4.2
|
75.9
|
1.0
|
CB
|
C:LYS181
|
4.3
|
76.5
|
1.0
|
PB
|
C:GDP361
|
4.4
|
15.1
|
1.0
|
N
|
C:THR182
|
4.5
|
75.9
|
1.0
|
CD
|
C:LYS181
|
4.5
|
77.2
|
1.0
|
C
|
C:GLY42
|
4.5
|
75.3
|
1.0
|
NE
|
C:ARG179
|
4.5
|
65.8
|
1.0
|
CA
|
C:GLY42
|
4.6
|
74.3
|
1.0
|
CB
|
C:GLU43
|
4.6
|
75.5
|
1.0
|
O2B
|
C:GDP361
|
4.6
|
14.0
|
1.0
|
NZ
|
C:LYS46
|
4.8
|
70.7
|
1.0
|
C
|
C:LYS181
|
4.9
|
75.7
|
1.0
|
|
Reference:
K.C.Slep,
M.A.Kercher,
T.Wieland,
C.K.Chen,
M.I.Simon,
P.B.Sigler.
Molecular Architecture of G{Alpha}O and the Structural Basis For RGS16-Mediated Deactivation. Proc.Natl.Acad.Sci.Usa V. 105 6243 2008.
ISSN: ISSN 0027-8424
PubMed: 18434540
DOI: 10.1073/PNAS.0801569105
Page generated: Wed Jul 31 17:21:53 2024
|