Chemical elements
  Fluorine
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    PDB 16pk-1c8m
    PDB 1c9d-1eau
    PDB 1ec0-1grn
    PDB 1gs4-1j97
    PDB 1jdj-1mu8
    PDB 1mue-1oyt
    PDB 1oz1-1rby
    PDB 1rbz-1tu6
    PDB 1tuy-1w9i
    PDB 1w9j-1yw2
    PDB 1yw9-2ax8
    PDB 2ax9-2dqt
    PDB 2dqu-2ftk
    PDB 2fvd-2hhn
    PDB 2hiw-2izs
    PDB 2j51-2onh
    PDB 2oo8-2pow
    PDB 2pq9-2qzl
    PDB 2qzo-2vev
    PDB 2vew-2wf7
    PDB 2wf8-2xhd
    PDB 2xkk-3ar9
    PDB 3az8-3cej
      3az8
      3b12
      3b2q
      3b2w
      3b5r
      3b66
      3b67
      3b68
      3b69
      3b8e
      3b8z
      3b9b
      3b9r
      3ba8
      3bbt
      3bcj
      3be2
      3bel
      3bgl
      3bgq
      3bh7
      3bl7
      3bny
      3bqm
      3bqn
      3brw
      3bys
      3byu
      3bz3
      3bzu
      3c1x
      3c27
      3c43
      3c45
      3c49
      3c4c
      3c4d
      3c5u
      3c7k
      3c7n
      3cct
      3ccw
      3ccz
      3cd0
      3cd7
      3cda
      3cdb
      3ce3
      3ceh
      3cej
    PDB 3cem-3dh3
    PDB 3dhf-3el7
    PDB 3el8-3fln
    PDB 3flq-3gc7
    PDB 3gc8-3h7w
    PDB 3h82-3i81
    PDB 3i8d-3jx1
    PDB 3jx2-3ktk
    PDB 3ktu-3lj6
    PDB 3lk9-3mqf
    PDB 3ms4-3nz7
    PDB 3o1g-3p4a
    PDB 3p4b-3ti1
    PDB 3tik-4acx
    PDB 4afe-4fk3
    PDB 4fod-7gch

Fluorine in the structure of Crystal Structure Of The Tyrosine Kinase Domain of the Hepatocyte Growth Factor Receptor C-Met in Complex With A Pyrrolopyridinepyridone Based Inhibitor (pdb 3ce3)






The binding sites of Fluorine atom in the structure of Crystal Structure Of The Tyrosine Kinase Domain of the Hepatocyte Growth Factor Receptor C-Met in Complex With A Pyrrolopyridinepyridone Based Inhibitor (pdb code 3ce3). This binding sites where shown with 5.0 Angstroms radius around Fluorine atom.
The 3ce3 structure was solved by J.SACK, with X-Ray Crystallography technique, brief refinement statistics is given in the table below:
Resolution (A)50.0-2.4
Space groupP212121
a (A)43.040
b (A)49.137
c (A)159.324
alpha (°)90.00
beta (°)90.00
gamma (°)90.00
Rfactor (%)20.6
Rfree (%)27.5


Fluorine Binding Sites:

Fluorine binding site 1 out of 2 in 3ce3


Fluorine binding site 1 out of 2 in 3ce3
Click to enlarge
stereopicture of Fluorine binding site 1 out of 2 in 3ce3
Click to enlarge
Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 1 of Fluorine in the PDB 3ce3. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Fluorine atom, shown by VdW sphere
Residues shown as a stick model or VDW spheres: A: Val1092, A: Ala1108, A: Lys1110, A: Leu1157, A: Phe1223, A: 1fn1401,

conact list:


AtomAtomDistance (A)
FCB A:Val10924.84
FCG1 A:Val10923.44
FCB A:Ala11084.37
FCB A:Lys11104.66
FCE A:Lys11104.11
FCD A:Lys11103.76
FCG A:Lys11103.50
FCD1 A:Leu11573.93
FCE1 A:Phe12234.97
FC11 A:1fn14013.73
FC1 A:1fn14014.72
FC8 A:1fn14012.36
FC6 A:1fn14013.51
FC5 A:1fn14013.81
FC13 A:1fn14011.39
FC10 A:1fn14014.24
FO7 A:1fn14012.66
FC9 A:1fn14013.68
FC12 A:1fn14012.50
FF14 A:1fn14010.00
FN15 A:1fn14014.88

interactive model:


Fluorine binding site 2 out of 2 in 3ce3


Fluorine binding site 2 out of 2 in 3ce3
Click to enlarge
stereopicture of Fluorine binding site 2 out of 2 in 3ce3
Click to enlarge
Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 2 of Fluorine in the PDB 3ce3. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Fluorine atom, shown by VdW sphere
Residues shown as a stick model or VDW spheres: A: Phe1134, A: Val1139, A: Leu1195, A: Phe1200, A: His1202, A: Val1220, A: Ala1221, A: 1fn1401,

conact list:


AtomAtomDistance (A)
FCE2 A:Phe11344.14
FCD2 A:Phe11344.44
FCG1 A:Val11394.08
FCD1 A:Leu11953.66
FCD2 A:Leu11954.36
FCG A:Leu11954.66
FCE2 A:Phe12004.32
FCZ A:Phe12004.99
FNE2 A:His12024.27
FCD2 A:His12023.90
FCG A:His12024.93
FO A:Val12203.95
FCB A:Val12204.70
FC A:Val12204.33
FCG1 A:Val12203.63
FO A:Ala12214.87
FN A:Ala12214.52
FC A:Ala12214.73
FCA A:Ala12214.36
FC31 A:1fn14012.18
FC32 A:1fn14011.24
FF35 A:1fn14010.00
FC34 A:1fn14013.61
FC33 A:1fn14012.35
FC30 A:1fn14013.46
FC26 A:1fn14014.02

interactive model:




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