Fluorine »
PDB 3d3e-3du8 »
3d4l »
Fluorine in PDB 3d4l: Human Dipeptidyl Peptidase IV/CD26 in Complex with A Novel Inhibitor
Enzymatic activity of Human Dipeptidyl Peptidase IV/CD26 in Complex with A Novel Inhibitor
All present enzymatic activity of Human Dipeptidyl Peptidase IV/CD26 in Complex with A Novel Inhibitor:
3.4.14.5;
3.4.14.5;
Protein crystallography data
The structure of Human Dipeptidyl Peptidase IV/CD26 in Complex with A Novel Inhibitor, PDB code: 3d4l
was solved by
G.Scapin,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 30.00 / 2.00 |
| Space group | P 21 21 21 |
| Cell size a, b, c (Å), α, β, γ (°) | 118.435, 125.749, 137.175, 90.00, 90.00, 90.00 |
| R / Rfree (%) | n/a / n/a |
Other elements in 3d4l:
The structure of Human Dipeptidyl Peptidase IV/CD26 in Complex with A Novel Inhibitor also contains other interesting chemical elements:
| Sodium | (Na) | 1 atom |
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Human Dipeptidyl Peptidase IV/CD26 in Complex with A Novel Inhibitor
(pdb code 3d4l). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 4 binding sites of Fluorine where determined in the Human Dipeptidyl Peptidase IV/CD26 in Complex with A Novel Inhibitor, PDB code: 3d4l:
Jump to Fluorine binding site number: 1; 2; 3; 4;
In total 4 binding sites of Fluorine where determined in the Human Dipeptidyl Peptidase IV/CD26 in Complex with A Novel Inhibitor, PDB code: 3d4l:
Jump to Fluorine binding site number: 1; 2; 3; 4;
Fluorine binding site 1 out of 4 in 3d4l
Go back to
Fluorine Binding Sites List in 3d4l
Fluorine binding site 1 out
of 4 in the Human Dipeptidyl Peptidase IV/CD26 in Complex with A Novel Inhibitor
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 1 of Human Dipeptidyl Peptidase IV/CD26 in Complex with A Novel Inhibitor within 5.0Å range:
|
Fluorine binding site 2 out of 4 in 3d4l
Go back to
Fluorine Binding Sites List in 3d4l
Fluorine binding site 2 out
of 4 in the Human Dipeptidyl Peptidase IV/CD26 in Complex with A Novel Inhibitor
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 2 of Human Dipeptidyl Peptidase IV/CD26 in Complex with A Novel Inhibitor within 5.0Å range:
|
Fluorine binding site 3 out of 4 in 3d4l
Go back to
Fluorine Binding Sites List in 3d4l
Fluorine binding site 3 out
of 4 in the Human Dipeptidyl Peptidase IV/CD26 in Complex with A Novel Inhibitor
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 3 of Human Dipeptidyl Peptidase IV/CD26 in Complex with A Novel Inhibitor within 5.0Å range:
|
Fluorine binding site 4 out of 4 in 3d4l
Go back to
Fluorine Binding Sites List in 3d4l
Fluorine binding site 4 out
of 4 in the Human Dipeptidyl Peptidase IV/CD26 in Complex with A Novel Inhibitor
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 4 of Human Dipeptidyl Peptidase IV/CD26 in Complex with A Novel Inhibitor within 5.0Å range:
|
Reference:
G.B.Liang,
X.Qian,
T.Biftu,
S.Singh,
Y.D.Gao,
G.Scapin,
S.Patel,
B.Leiting,
R.Patel,
J.Wu,
X.Zhang,
N.A.Thornberry,
A.E.Weber.
Discovery of New Binding Elements in Dpp-4 Inhibition and Their Applications in Novel Dpp-4 Inhibitor Design. Bioorg.Med.Chem.Lett. V. 18 3706 2008.
ISSN: ISSN 0960-894X
PubMed: 18524582
DOI: 10.1016/J.BMCL.2008.05.061
Page generated: Wed Jul 31 17:51:31 2024
ISSN: ISSN 0960-894X
PubMed: 18524582
DOI: 10.1016/J.BMCL.2008.05.061
Last articles
Zn in 9JPJZn in 9JP7
Zn in 9JPK
Zn in 9JPL
Zn in 9GN6
Zn in 9GN7
Zn in 9GKU
Zn in 9GKW
Zn in 9GKX
Zn in 9GL0
