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Fluorine in PDB 3dkl: Crystal Structure of Phosphorylated Mimic Form of Human Nampt Complexed with Benzamide and Phosphoribosyl Pyrophosphate
Enzymatic activity of Crystal Structure of Phosphorylated Mimic Form of Human Nampt Complexed with Benzamide and Phosphoribosyl Pyrophosphate
All present enzymatic activity of Crystal Structure of Phosphorylated Mimic Form of Human Nampt Complexed with Benzamide and Phosphoribosyl Pyrophosphate:
2.4.2.12;
2.4.2.12;
Protein crystallography data
The structure of Crystal Structure of Phosphorylated Mimic Form of Human Nampt Complexed with Benzamide and Phosphoribosyl Pyrophosphate, PDB code: 3dkl
was solved by
M.Ho,
E.S.Burgos,
S.C.Almo,
V.L.Schramm,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 28.56 / 1.89 |
| Space group | P 1 21 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 61.127, 106.589, 83.240, 90.00, 96.78, 90.00 |
| R / Rfree (%) | 17.7 / 21.4 |
Other elements in 3dkl:
The structure of Crystal Structure of Phosphorylated Mimic Form of Human Nampt Complexed with Benzamide and Phosphoribosyl Pyrophosphate also contains other interesting chemical elements:
| Magnesium | (Mg) | 4 atoms |
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of Phosphorylated Mimic Form of Human Nampt Complexed with Benzamide and Phosphoribosyl Pyrophosphate
(pdb code 3dkl). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 6 binding sites of Fluorine where determined in the Crystal Structure of Phosphorylated Mimic Form of Human Nampt Complexed with Benzamide and Phosphoribosyl Pyrophosphate, PDB code: 3dkl:
Jump to Fluorine binding site number: 1; 2; 3; 4; 5; 6;
In total 6 binding sites of Fluorine where determined in the Crystal Structure of Phosphorylated Mimic Form of Human Nampt Complexed with Benzamide and Phosphoribosyl Pyrophosphate, PDB code: 3dkl:
Jump to Fluorine binding site number: 1; 2; 3; 4; 5; 6;
Fluorine binding site 1 out of 6 in 3dkl
Go back to
Fluorine Binding Sites List in 3dkl
Fluorine binding site 1 out
of 6 in the Crystal Structure of Phosphorylated Mimic Form of Human Nampt Complexed with Benzamide and Phosphoribosyl Pyrophosphate
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 1 of Crystal Structure of Phosphorylated Mimic Form of Human Nampt Complexed with Benzamide and Phosphoribosyl Pyrophosphate within 5.0Å range:
|
Fluorine binding site 2 out of 6 in 3dkl
Go back to
Fluorine Binding Sites List in 3dkl
Fluorine binding site 2 out
of 6 in the Crystal Structure of Phosphorylated Mimic Form of Human Nampt Complexed with Benzamide and Phosphoribosyl Pyrophosphate
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 2 of Crystal Structure of Phosphorylated Mimic Form of Human Nampt Complexed with Benzamide and Phosphoribosyl Pyrophosphate within 5.0Å range:
|
Fluorine binding site 3 out of 6 in 3dkl
Go back to
Fluorine Binding Sites List in 3dkl
Fluorine binding site 3 out
of 6 in the Crystal Structure of Phosphorylated Mimic Form of Human Nampt Complexed with Benzamide and Phosphoribosyl Pyrophosphate
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 3 of Crystal Structure of Phosphorylated Mimic Form of Human Nampt Complexed with Benzamide and Phosphoribosyl Pyrophosphate within 5.0Å range:
|
Fluorine binding site 4 out of 6 in 3dkl
Go back to
Fluorine Binding Sites List in 3dkl
Fluorine binding site 4 out
of 6 in the Crystal Structure of Phosphorylated Mimic Form of Human Nampt Complexed with Benzamide and Phosphoribosyl Pyrophosphate
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 4 of Crystal Structure of Phosphorylated Mimic Form of Human Nampt Complexed with Benzamide and Phosphoribosyl Pyrophosphate within 5.0Å range:
|
Fluorine binding site 5 out of 6 in 3dkl
Go back to
Fluorine Binding Sites List in 3dkl
Fluorine binding site 5 out
of 6 in the Crystal Structure of Phosphorylated Mimic Form of Human Nampt Complexed with Benzamide and Phosphoribosyl Pyrophosphate
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 5 of Crystal Structure of Phosphorylated Mimic Form of Human Nampt Complexed with Benzamide and Phosphoribosyl Pyrophosphate within 5.0Å range:
|
Fluorine binding site 6 out of 6 in 3dkl
Go back to
Fluorine Binding Sites List in 3dkl
Fluorine binding site 6 out
of 6 in the Crystal Structure of Phosphorylated Mimic Form of Human Nampt Complexed with Benzamide and Phosphoribosyl Pyrophosphate
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 6 of Crystal Structure of Phosphorylated Mimic Form of Human Nampt Complexed with Benzamide and Phosphoribosyl Pyrophosphate within 5.0Å range:
|
Reference:
E.S.Burgos,
M.C.Ho,
S.C.Almo,
V.L.Schramm.
A Phosphoenzyme Mimic, Overlapping Catalytic Sites and Reaction Coordinate Motion For Human Nampt. Proc.Natl.Acad.Sci.Usa V. 106 13748 2009.
ISSN: ISSN 0027-8424
PubMed: 19666527
DOI: 10.1073/PNAS.0903898106
Page generated: Sun Dec 13 11:44:51 2020
ISSN: ISSN 0027-8424
PubMed: 19666527
DOI: 10.1073/PNAS.0903898106
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