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Atomistry » Fluorine » PDB 3dv3-3ev4 » 3dya » |
Fluorine in PDB 3dya: Hiv-1 Rt with Non-Nucleoside Inhibitor Annulated Pyrazole 1Enzymatic activity of Hiv-1 Rt with Non-Nucleoside Inhibitor Annulated Pyrazole 1
All present enzymatic activity of Hiv-1 Rt with Non-Nucleoside Inhibitor Annulated Pyrazole 1:
2.7.7.49; 2.7.7.7; 3.1.26.4; Protein crystallography data
The structure of Hiv-1 Rt with Non-Nucleoside Inhibitor Annulated Pyrazole 1, PDB code: 3dya
was solved by
S.F.Harris,
A.Villasenor,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 3dya:
The structure of Hiv-1 Rt with Non-Nucleoside Inhibitor Annulated Pyrazole 1 also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Hiv-1 Rt with Non-Nucleoside Inhibitor Annulated Pyrazole 1
(pdb code 3dya). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Hiv-1 Rt with Non-Nucleoside Inhibitor Annulated Pyrazole 1, PDB code: 3dya: Fluorine binding site 1 out of 1 in 3dyaGo back to Fluorine Binding Sites List in 3dya
Fluorine binding site 1 out
of 1 in the Hiv-1 Rt with Non-Nucleoside Inhibitor Annulated Pyrazole 1
Mono view Stereo pair view
Reference:
Z.K.Sweeney,
S.F.Harris,
S.F.Arora,
H.Javanbakht,
Y.Li,
J.Fretland,
J.P.Davidson,
J.R.Billedeau,
S.K.Gleason,
D.Hirschfeld,
J.J.Kennedy-Smith,
T.Mirzadegan,
R.Roetz,
M.Smith,
S.Sperry,
J.M.Suh,
J.Wu,
S.Tsing,
A.G.Villasenor,
A.Paul,
G.Su,
G.Heilek,
J.Q.Hang,
A.S.Zhou,
J.A.Jernelius,
F.J.Zhang,
K.Klumpp.
Design of Annulated Pyrazoles As Inhibitors of Hiv-1 Reverse Transcriptase J.Med.Chem. V. 51 7449 2008.
Page generated: Wed Jul 31 18:11:56 2024
ISSN: ISSN 0022-2623 PubMed: 19007201 DOI: 10.1021/JM800527X |
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