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Atomistry » Fluorine » PDB 3dv3-3ev4 » 3ekk » |
Fluorine in PDB 3ekk: Insulin Receptor Kinase Complexed with An InhibitorEnzymatic activity of Insulin Receptor Kinase Complexed with An Inhibitor
All present enzymatic activity of Insulin Receptor Kinase Complexed with An Inhibitor:
2.7.10.1; Protein crystallography data
The structure of Insulin Receptor Kinase Complexed with An Inhibitor, PDB code: 3ekk
was solved by
S.Chamberlain,
C.Atkins,
F.Deanda,
M.Dumble,
R.Gerding,
A.Groy,
S.Korenchuk,
R.Kumar,
H.Lei,
R.Mook,
G.Moorthy,
A.Redman,
J.Rowland,
P.Sabbatini,
L.Shewchuk,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Insulin Receptor Kinase Complexed with An Inhibitor
(pdb code 3ekk). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Insulin Receptor Kinase Complexed with An Inhibitor, PDB code: 3ekk: Fluorine binding site 1 out of 1 in 3ekkGo back to Fluorine Binding Sites List in 3ekk
Fluorine binding site 1 out
of 1 in the Insulin Receptor Kinase Complexed with An Inhibitor
Mono view Stereo pair view
Reference:
S.D.Chamberlain,
J.W.Wilson,
F.Deanda,
S.Patnaik,
A.M.Redman,
B.Yang,
L.Shewchuk,
P.Sabbatini,
M.A.Leesnitzer,
A.Groy,
C.Atkins,
R.Gerding,
A.M.Hassell,
H.Lei,
R.A.Mook,
G.Moorthy,
J.L.Rowand,
K.L.Stevens,
R.Kumar,
J.B.Shotwell.
Discovery of 4,6-Bis-Anilino-1H-Pyrrolo[2,3-D]Pyrimidines: Potent Inhibitors of the Igf-1R Receptor Tyrosine Kinase. Bioorg.Med.Chem.Lett. V. 19 469 2009.
Page generated: Sun Dec 13 11:45:29 2020
ISSN: ISSN 0960-894X PubMed: 19056263 DOI: 10.1016/J.BMCL.2008.11.046 |
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