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Atomistry » Fluorine » PDB 3ewh-3flq » 3fln | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 3ewh-3flq » 3fln » |
Fluorine in PDB 3fln: P38 Kinase Crystal Structure in Complex with R1487Enzymatic activity of P38 Kinase Crystal Structure in Complex with R1487
All present enzymatic activity of P38 Kinase Crystal Structure in Complex with R1487:
2.7.11.24; Protein crystallography data
The structure of P38 Kinase Crystal Structure in Complex with R1487, PDB code: 3fln
was solved by
A.Kuglstatter,
M.Knapp,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the P38 Kinase Crystal Structure in Complex with R1487
(pdb code 3fln). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the P38 Kinase Crystal Structure in Complex with R1487, PDB code: 3fln: Jump to Fluorine binding site number: 1; 2; Fluorine binding site 1 out of 2 in 3flnGo back to Fluorine Binding Sites List in 3fln
Fluorine binding site 1 out
of 2 in the P38 Kinase Crystal Structure in Complex with R1487
Mono view Stereo pair view
Fluorine binding site 2 out of 2 in 3flnGo back to Fluorine Binding Sites List in 3fln
Fluorine binding site 2 out
of 2 in the P38 Kinase Crystal Structure in Complex with R1487
Mono view Stereo pair view
Reference:
M.Soth,
A.Kuglstatter,
D.Goldstein.
The Discovery of Pamapimod, R1503 and R1487 As Orally Bioavailable and Highly Selective Inhibitors of P38 Map Kinase To Be Published.
Page generated: Sun Dec 13 11:46:07 2020
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