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Atomistry » Fluorine » PDB 3fls-3g70 » 3flw | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Fluorine » PDB 3fls-3g70 » 3flw » |
Fluorine in PDB 3flw: P38 Kinase Crystal Structure in Complex with PamapimodEnzymatic activity of P38 Kinase Crystal Structure in Complex with Pamapimod
All present enzymatic activity of P38 Kinase Crystal Structure in Complex with Pamapimod:
2.7.11.24; Protein crystallography data
The structure of P38 Kinase Crystal Structure in Complex with Pamapimod, PDB code: 3flw
was solved by
A.Kuglstatter,
M.Ghate,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the P38 Kinase Crystal Structure in Complex with Pamapimod
(pdb code 3flw). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the P38 Kinase Crystal Structure in Complex with Pamapimod, PDB code: 3flw: Jump to Fluorine binding site number: 1; 2; Fluorine binding site 1 out of 2 in 3flwGo back to Fluorine Binding Sites List in 3flw
Fluorine binding site 1 out
of 2 in the P38 Kinase Crystal Structure in Complex with Pamapimod
Mono view Stereo pair view
Fluorine binding site 2 out of 2 in 3flwGo back to Fluorine Binding Sites List in 3flw
Fluorine binding site 2 out
of 2 in the P38 Kinase Crystal Structure in Complex with Pamapimod
Mono view Stereo pair view
Reference:
M.Soth,
A.Kuglstatter,
D.Goldstein.
The Discovery of Pamapimod, R1503 and R1487 As Orally Bioavailable and Highly Selective Inhibitors of P38 Map Kinase To Be Published.
Page generated: Sun Dec 13 11:46:12 2020
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