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Atomistry » Fluorine » PDB 3fls-3g70 » 3fuf » |
Fluorine in PDB 3fuf: Leukotriene A4 Hydrolase in Complex with Fragment 5- Fluoroindole and BestatinEnzymatic activity of Leukotriene A4 Hydrolase in Complex with Fragment 5- Fluoroindole and Bestatin
All present enzymatic activity of Leukotriene A4 Hydrolase in Complex with Fragment 5- Fluoroindole and Bestatin:
3.3.2.6; Protein crystallography data
The structure of Leukotriene A4 Hydrolase in Complex with Fragment 5- Fluoroindole and Bestatin, PDB code: 3fuf
was solved by
D.R.Davies,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 3fuf:
The structure of Leukotriene A4 Hydrolase in Complex with Fragment 5- Fluoroindole and Bestatin also contains other interesting chemical elements:
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Leukotriene A4 Hydrolase in Complex with Fragment 5- Fluoroindole and Bestatin
(pdb code 3fuf). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Leukotriene A4 Hydrolase in Complex with Fragment 5- Fluoroindole and Bestatin, PDB code: 3fuf: Fluorine binding site 1 out of 1 in 3fufGo back to![]() ![]()
Fluorine binding site 1 out
of 1 in the Leukotriene A4 Hydrolase in Complex with Fragment 5- Fluoroindole and Bestatin
![]() Mono view ![]() Stereo pair view
Reference:
D.R.Davies,
B.Mamat,
O.T.Magnusson,
J.Christensen,
M.H.Haraldsson,
R.Mishra,
B.Pease,
E.Hansen,
J.Singh,
D.Zembower,
H.Kim,
A.S.Kiselyov,
A.B.Burgin,
M.E.Gurney,
L.J.Stewart.
Discovery of Leukotriene A4 Hydrolase Inhibitors Using Metabolomics Biased Fragment Crystallography. J.Med.Chem. V. 52 4694 2009.
Page generated: Wed Jul 31 18:41:26 2024
ISSN: ISSN 0022-2623 PubMed: 19618939 DOI: 10.1021/JM900259H |
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