Atomistry » Fluorine » PDB 3fls-3g70 » 3fxz
Atomistry »
  Fluorine »
    PDB 3fls-3g70 »
      3fxz »

Fluorine in PDB 3fxz: Crystal Structure of PAK1 Kinase Domain with Ruthenium Complex Lambda-FL172

Enzymatic activity of Crystal Structure of PAK1 Kinase Domain with Ruthenium Complex Lambda-FL172

All present enzymatic activity of Crystal Structure of PAK1 Kinase Domain with Ruthenium Complex Lambda-FL172:
2.7.11.1;

Protein crystallography data

The structure of Crystal Structure of PAK1 Kinase Domain with Ruthenium Complex Lambda-FL172, PDB code: 3fxz was solved by J.Maksimoska, R.Marmorstein, E.Meggers, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 26.38 / 1.64
Space group C 2 2 21
Cell size a, b, c (Å), α, β, γ (°) 52.183, 103.475, 122.653, 90.00, 90.00, 90.00
R / Rfree (%) 19.5 / 21.8

Other elements in 3fxz:

The structure of Crystal Structure of PAK1 Kinase Domain with Ruthenium Complex Lambda-FL172 also contains other interesting chemical elements:

Ruthenium (Ru) 1 atom
Chlorine (Cl) 1 atom

Fluorine Binding Sites:

The binding sites of Fluorine atom in the Crystal Structure of PAK1 Kinase Domain with Ruthenium Complex Lambda-FL172 (pdb code 3fxz). This binding sites where shown within 5.0 Angstroms radius around Fluorine atom.
In total only one binding site of Fluorine was determined in the Crystal Structure of PAK1 Kinase Domain with Ruthenium Complex Lambda-FL172, PDB code: 3fxz:

Fluorine binding site 1 out of 1 in 3fxz

Go back to Fluorine Binding Sites List in 3fxz
Fluorine binding site 1 out of 1 in the Crystal Structure of PAK1 Kinase Domain with Ruthenium Complex Lambda-FL172


Mono view


Stereo pair view

A full contact list of Fluorine with other atoms in the F binding site number 1 of Crystal Structure of PAK1 Kinase Domain with Ruthenium Complex Lambda-FL172 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:F1

b:27.3
occ:1.00
 F2 A:FLL1 0.0 27.3 1.0
C38 A:FLL1 1.3 24.8 1.0
C39 A:FLL1 2.3 24.3 1.0
C37 A:FLL1 2.3 24.9 1.0
O A:HOH95 3.1 41.4 1.0
NE A:ARG299 3.3 31.2 1.0
CD A:ARG299 3.4 31.5 1.0
O A:HOH90 3.5 43.7 1.0
N23 A:FLL1 3.5 25.8 1.0
CG A:ARG299 3.6 26.6 1.0
C36 A:FLL1 3.6 24.9 1.0
O A:HOH70 3.7 42.2 1.0
O A:HOH190 3.8 39.9 1.0
C40 A:FLL1 4.0 24.9 1.0
CG2 A:VAL284 4.0 28.7 1.0
O A:HOH65 4.1 52.6 1.0
CZ A:ARG299 4.1 32.9 1.0
O A:HOH63 4.4 55.8 1.0
O A:HOH68 4.6 32.6 1.0
NH2 A:ARG299 4.6 34.8 1.0
CB A:ARG299 4.7 25.6 1.0
OG A:SER281 4.8 57.8 1.0
CG1 A:VAL284 4.8 27.5 1.0
NH1 A:ARG299 4.8 32.3 1.0
C35 A:FLL1 4.9 24.2 1.0
C19 A:FLL1 4.9 36.5 1.0

Reference:

J.Maksimoska, L.Feng, K.Harms, C.Yi, J.Kissil, R.Marmorstein, E.Meggers. Targeting Large Kinase Active Site with Rigid, Bulky Octahedral Ruthenium Complexes J.Am.Chem.Soc. V. 130 15764 2008.
ISSN: ISSN 0002-7863
PubMed: 18973295
Page generated: Wed Jul 31 18:42:16 2024

Last articles

Zn in 9JPJ
Zn in 9JP7
Zn in 9JPK
Zn in 9JPL
Zn in 9GN6
Zn in 9GN7
Zn in 9GKU
Zn in 9GKW
Zn in 9GKX
Zn in 9GL0
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy