Fluorine »
PDB 3fls-3g70 »
3g1v »
Fluorine in PDB 3g1v: Crystal Structure of the Mutant D70G of Orotidine 5'- Monophosphate Decarboxylase From Methanobacterium Thermoautotrophicum Complexed with 5-Fluorouridine 5'- Monophosphate
Enzymatic activity of Crystal Structure of the Mutant D70G of Orotidine 5'- Monophosphate Decarboxylase From Methanobacterium Thermoautotrophicum Complexed with 5-Fluorouridine 5'- Monophosphate
All present enzymatic activity of Crystal Structure of the Mutant D70G of Orotidine 5'- Monophosphate Decarboxylase From Methanobacterium Thermoautotrophicum Complexed with 5-Fluorouridine 5'- Monophosphate:
4.1.1.23;
4.1.1.23;
Protein crystallography data
The structure of Crystal Structure of the Mutant D70G of Orotidine 5'- Monophosphate Decarboxylase From Methanobacterium Thermoautotrophicum Complexed with 5-Fluorouridine 5'- Monophosphate, PDB code: 3g1v
was solved by
A.A.Fedorov,
E.V.Fedorov,
K.K.Chan,
J.A.Gerlt,
S.C.Almo,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 24.93 / 1.30 |
| Space group | P 41 |
| Cell size a, b, c (Å), α, β, γ (°) | 56.620, 56.620, 127.443, 90.00, 90.00, 90.00 |
| R / Rfree (%) | 19.3 / 21.1 |
Other elements in 3g1v:
The structure of Crystal Structure of the Mutant D70G of Orotidine 5'- Monophosphate Decarboxylase From Methanobacterium Thermoautotrophicum Complexed with 5-Fluorouridine 5'- Monophosphate also contains other interesting chemical elements:
| Chlorine | (Cl) | 2 atoms |
Fluorine Binding Sites:
The binding sites of Fluorine atom in the Crystal Structure of the Mutant D70G of Orotidine 5'- Monophosphate Decarboxylase From Methanobacterium Thermoautotrophicum Complexed with 5-Fluorouridine 5'- Monophosphate
(pdb code 3g1v). This binding sites where shown within
5.0 Angstroms radius around Fluorine atom.
In total 2 binding sites of Fluorine where determined in the Crystal Structure of the Mutant D70G of Orotidine 5'- Monophosphate Decarboxylase From Methanobacterium Thermoautotrophicum Complexed with 5-Fluorouridine 5'- Monophosphate, PDB code: 3g1v:
Jump to Fluorine binding site number: 1; 2;
In total 2 binding sites of Fluorine where determined in the Crystal Structure of the Mutant D70G of Orotidine 5'- Monophosphate Decarboxylase From Methanobacterium Thermoautotrophicum Complexed with 5-Fluorouridine 5'- Monophosphate, PDB code: 3g1v:
Jump to Fluorine binding site number: 1; 2;
Fluorine binding site 1 out of 2 in 3g1v
Go back to
Fluorine Binding Sites List in 3g1v
Fluorine binding site 1 out
of 2 in the Crystal Structure of the Mutant D70G of Orotidine 5'- Monophosphate Decarboxylase From Methanobacterium Thermoautotrophicum Complexed with 5-Fluorouridine 5'- Monophosphate
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 1 of Crystal Structure of the Mutant D70G of Orotidine 5'- Monophosphate Decarboxylase From Methanobacterium Thermoautotrophicum Complexed with 5-Fluorouridine 5'- Monophosphate within 5.0Å range:
|
Fluorine binding site 2 out of 2 in 3g1v
Go back to
Fluorine Binding Sites List in 3g1v
Fluorine binding site 2 out
of 2 in the Crystal Structure of the Mutant D70G of Orotidine 5'- Monophosphate Decarboxylase From Methanobacterium Thermoautotrophicum Complexed with 5-Fluorouridine 5'- Monophosphate
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Fluorine with other atoms in the F binding
site number 2 of Crystal Structure of the Mutant D70G of Orotidine 5'- Monophosphate Decarboxylase From Methanobacterium Thermoautotrophicum Complexed with 5-Fluorouridine 5'- Monophosphate within 5.0Å range:
|
Reference:
K.K.Chan,
B.M.Wood,
A.A.Fedorov,
E.V.Fedorov,
H.J.Imker,
T.L.Amyes,
J.P.Richard,
S.C.Almo,
J.A.Gerlt.
Mechanism of the Orotidine 5'-Monophosphate Decarboxylase-Catalyzed Reaction: Evidence For Substrate Destabilization. Biochemistry V. 48 5518 2009.
ISSN: ISSN 0006-2960
PubMed: 19435314
DOI: 10.1021/BI900623R
Page generated: Sun Dec 13 11:46:30 2020
ISSN: ISSN 0006-2960
PubMed: 19435314
DOI: 10.1021/BI900623R
Last articles
Zn in 8WB0Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
